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Advances in Veterinary Science and Comparative Medicine, Volume 33: Vaccine Biotechnology presents advances in the field of vaccinology and approaches in the development of vaccines.

Biotechnology --- Technology --- Biological Products --- Biological Science Disciplines --- Technology, Industry, and Agriculture --- Complex Mixtures --- Natural Science Disciplines --- Disciplines and Occupations --- Technology, Industry, Agriculture --- Chemicals and Drugs --- Vaccines

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Human medicine --- Science --- Complementary Therapies --- Therapeutics --- Natural Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Spiritual Therapies --- Research

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"Molecular Aspects of Alcohol and Nutrition is a valuable resource for nutrition researchers and nutritionists who study or treat alcohol-related diseases. Experts from across the field of alcohol research explain how alcohol disrupts normal fat, carbohydrate, and protein metabolic processes occurring in the liver as well as other parts of the body. The book discusses how this can lead to alcoholic liver disease (ALD) as well as contribute to the onset of Type 2 diabetes and the metabolic syndrome. It also explores how alcohol affects nutrient absorption in the gastrointestinal tract and can lead to anemia and reduced amounts of fat soluble vitamins. This book explores both the primary and secondary consequences of alcohol consumption. Chapters in the first section investigate the basic science of alcohol metabolism focusing on how alcohol and its toxic metabolites disrupt and impair normal nutrient regulation at the molecular level. Further chapters explore how alcohol affects many extra-hepatic organs and tissues as well as the secondary consequences of alcohol consumption such as reduced levels of minerals like magnesium, calcium, and trace elements like zinc."--

Ethanol --- Molecular Biology --- Alcoholism --- Nutrition Disorders --- Genetics --- Alcohol-Related Disorders --- Biochemistry --- Nutritional and Metabolic Diseases --- Alcohols --- Substance-Related Disorders --- Biology --- Biological Science Disciplines --- Chemistry --- Organic Chemicals --- Diseases --- Natural Science Disciplines --- Mental Disorders

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"The third edition of Contact Lens Optics and Lens Design is clearer and more accessible than ever before. Without assuming detailed prior knowledge of optics and ophthalmic lenses, Professor Douthwaite provides a straightforward introduction and, moving from a restatement of basic knowledge, builds solutions to the vast majority of contact lens optics problems likely to be encountered by the student or practitioner." "The new Contact Lens Optics and Lens Design is indispensable reading for all undergraduate optometry students and will also be invaluable to contact lens practitioners in helping them cope rapidly and efficiently with the problems of everyday contact lens fitting."--Jacket.

Physics --- Lenses --- Engineering --- Technology, Industry, and Agriculture --- Natural Science Disciplines --- Optical Devices --- Equipment and Supplies --- Technology, Industry, Agriculture --- Disciplines and Occupations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Optics and Photonics --- Contact Lenses

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High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies is an authoritative reference on the current state-of-the-art in sample preparation techniques for bioanalysis. This book focuses on high throughput (rapid productivity) techniques and describes exactly how to perform and automate these methodologies, including useful strategies for method development and optimization. A thorough review of the literature is included within each of these chapters describing high throughput sample preparation techniques: protein removal by precipitation; equilibrium dialysis and ultrafiltration; liquid-liquid extraction; solid-phase extraction; and various on-line techniques. The text begins with an introductory overview of the role of bioanalysis in pharmaceutical drug development. Fundamental understanding of the strategies for sample preparation is reinforced next, along with essential concepts in extraction chemistry. Several chapters introduce and discuss microplates, accessory products and automation devices. Particular strategies for efficient use of automation within a bioanalytical laboratory are also presented. The subject material then reviews protein precipitation, liquid-liquid extraction, solid-phase extraction and various on-line sample preparation approaches. The book concludes with information on recent advances in sample preparation, such as solid-phase extraction in a card format and higher density extraction plates. Important objectives that can be accomplished when the strategies presented in this book are followed include: improved efficiency in moving discovery compounds to preclinical status with robust analytical methods; return on investment in automation for sample preparation; and improved knowledge and expertise of laboratory staff. Shows the reader exactly how to perform modern bioanalytical sample preparation techniques, complete with detailed strategies Thorough literature review and summary of published information Detailed discussion and examples of the method development process.

Drugs --- Pharmaceutical industry --- Metabolic Phenomena --- Pharmacological Phenomena --- Kinetics --- Natural Science Disciplines --- Investigative Techniques --- Fluids and Secretions --- Chemicals and Drugs --- Evaluation Studies as Topic --- Drug Discovery --- Body Fluids --- Chemistry --- Methods --- Drug Evaluation, Preclinical --- Chemistry Techniques, Analytical --- Metabolism --- Pharmacokinetics --- Pharmaceutical Preparations --- Biochemical Phenomena --- Phenomena and Processes --- Physiological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Anatomy --- Disciplines and Occupations --- Chemical Phenomena --- Analysis --- Technological innovations