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Over the last decades, interest in forensic toxicology has continually increased. Consequently, the discipline assumed a leading role, becoming one of the reference sciences for elucidating events of judicial importance. The need to reconcile analytical problems (e.g., relating to the qualitative/quantitative analysis of substances of abuse in complex biological matrices) with judicial requirements (i.e., providing data that can be used as documentary evidence in proceedings) makes the discipline unique among all "analytical" sciences. Thus, the availability of validated procedures, the constant monitoring of analytical performance through quality assurance protocols, the availability of certified "in matrix" standards, and the analytical problems underlying the analysis of new psychoactive substances in the blood and other biological fluids represent the challenges of modern forensic toxicology. The correct interpretation of analytical data, especially to elucidate the extent of impairment induced by a certain substance, and "old" issues related to the correct interpretation of post-mortem data (given the impossibility of translating the therapeutic ranges defined in vivo) represent further areas of research and debate among scientists. Finally, the possibility of interacting with other disciplines (such as proteomics and social sciences) allows for extending the concept of analytical data acquisition/interpretation beyond the classical limits of forensic toxicology (for example, considering the influence of gender when interpreting the effect of a substance).

Cocaine abuse.

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'Freud on Coke' explores his use of the drug, its influence on his later thought, and the subsequent, complex relationship between psychology, psychiatry, drugs and culture.

Cocaine abuse. --- Freud, Sigmund,

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Cocaine industry --- Drug traffic --- Location

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Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral, pharmacological, and neurobiological determinants. While a complete understanding of cocaine abuse is currently beyond us, significant progress has been made in preclinical research on fundamental determinants of this disorder. These advances are critically reviewed in the first section of this volume. Important advances also have

Cocaine abuse --- Cocaine --- Behavior --- Cocaine-Related Disorders --- Cocaine. --- Pathophysiology. --- Treatment. --- Psychological aspects. --- drug effects. --- pharmacology. --- therapy. --- Psychopharmacology --- Cocaine addiction --- Cocaine habit --- Crack abuse --- Crack addiction --- Drug abuse --- Physiological aspects. --- Drug effects. --- Pharmacology. --- Therapy.

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De afgelopen jaren hebben de media herhaaldelijk bericht over cocaïne in vissersdorpen. Wordt hier inderdaad vaker drugs gebruikt of is de commotie een typisch voorbeeld van morele paniek, waarbij iets kleins wordt opgeblazen en buitenproportionele sociale reacties teweegbrengt? Dergelijke vragen nodigen volgens Dirk Korf uit tot een kritische beschouwing van politiecijfers en tot een analyse van ontwikkelingen in criminaliteitsbeleid en in de samenleving. Hij stelt in zijn oratie dat de teloorgang van tradities in maritieme gemeenschappen symbool staat voor ingrijpende veranderingen op het pl

Drug abuse and crime --- Cocaine abuse --- Criminology