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With the applications of prediction gaining momentum in fields such as enzymology and immunology, this volume presents an evaluation of present methods of expounding the various algorithms. These, when utilized on PCs or larger computers, can instantaneously take a primary amino acid sequence and produce a two- or three-dimensional image of the str.
Proteins --- Protein Conformation --- MODELS, MOLECULAR --- Conformation --- ultrastructure --- Conformation. --- Structure --- Mathematical models. --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Protein conformation --- Structure&delete& --- Mathematical models --- Proteins - Structure - Mathematical models. --- Proteins - Conformation. --- Models, Molecular --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Molecular Models --- Model, Molecular --- Molecular Model --- Molecular Conformation --- Molecular Structure --- Proteins - Conformation --- Proteins - ultrastructure --- PROTEINS --- PROTEIN CONFORMATION --- PROPERTIES
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biochemie --- General biochemistry --- proteïnen --- Protein Conformation --- Proteins --- Protéines --- physiology --- Structure --- Conformation --- Protein Conformation. --- Proteins. --- physiology. --- Structure. --- Conformation. --- 547.96 --- 547.96 Proteins --- Protéines --- Protein conformation --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Algemene biochemie --- Proteins - physiology. --- Proteins - Structure. --- Proteins - Conformation. --- Acqui 2006 --- PROTEINS --- CONFORMATION --- PHYSIOLOGY --- STRUCUTRE
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Proteins --- Drug development --- Drug Design --- Protein Conformation --- Crystallization --- Crystallography
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"Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of proteins."--Jacket.
Proteins --- Protein Conformation. --- Protéines --- chemistry. --- genetics. --- metabolism. --- Protein Conformation --- 577.122 --- 577.122 Protein metabolism --- Protein metabolism --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- chemistry --- genetics --- metabolism --- Acqui 2006
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Fundamentals of Protein Structure and Function Engelbert Buxbaum, Dr. rer. nat. This book serves as an introduction to the fundamentals of protein structure and function. Starting with their make up from simple building blocks called amino acids, the 3-dimensional structure of proteins is explained. This is followed by an introduction into enzymology and modern concepts of enzyme kinetics, taking into account the physiological and medical significance of this often neglected topic. Also covered in the text are enzymes, biocatalysts, enzyme kinetics, hemoglobin, myoglobin, prion proteins, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins into mitochondria, transport of proteins between cell compartments, transport of solutes across membranes, analytic techniques, protein-ligand interactions, protein purification, and protein structure, size and shape, emphasizing the link between protein structure, physiological function and medical significance. This book is an introductory text for researchers in protein biochemistry, molecular biology, cell biology, chemistry, biophysics and biomedical research. The book also makes an ideal textbook for graduate and advanced undergraduate courses in protein structure and function, and a supplementary text for related courses. About the Author Dr. Buxbaum is a biochemist with interest in enzymology and protein science. Dr. Buxbaum has been working on the biochemistry of membrane transport proteins for almost 20 years and has taught courses in biochemistry and molecular medicine at several universities. "The analytical descriptions of structure, biophysics and function of proteins is an extremely important aspect of today's education in biochemistry." Martin Sagermann, Ph.D. University of California, Santa Barbara
Proteins --- Structure --- Protein Conformation --- 577.122 --- 577.122 Protein metabolism --- Protein metabolism --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- physiology --- Proteins - Structure
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proteins --- cell structure --- chemical structure --- chemicophysical properties --- biological properties --- physiological functions --- Proteins --- PROTEINS --- Protein conformation --- CONFORMATION --- Physiology --- PHYSIOLOGY --- STRUCTURE --- Proteins. --- proteins. --- cell structure. --- chemical structure. --- chemicophysical properties. --- biological properties. --- physiological functions. --- Protéines. --- Protéines --- Study and teaching (Higher) --- Structure. --- Conformation. --- physiology. --- Étude et enseignement (supérieur) --- Physiologie.
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Computational structural biology has made tremendous progress over the last two decades, and this book provides a recent and broad overview of such computational methods in structural biology. It covers the impact of computational structural biology on protein structure prediction methods, macromolecular function and protein design, and key methods in drug discovery. It also addresses the computational challenges of experimental approaches in structural biology. In addition to reviewing the current state of computational structural biology, each chapter ends with a brief, visionary discussion
Computational biology. --- Protein folding --- Proteins --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Folding of proteins --- Biology --- Bioinformatics --- Computer simulation. --- Mathematical models. --- Structure --- Folding --- Conformation --- Computational biology --- Drug design. --- Nucleic acid conformation. --- Protein conformation. --- Protein folding. --- Rna. --- Methods. --- Computer simulation --- Mathematical models --- Proteins - Structure - Computer simulation --- Protein folding - Computer simulation --- Proteins - Structure - Mathematical models --- Protein folding - Mathematical models
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The prediction of the three-dimensional structure of a protein from its amino acid sequence is a problem faced by an increasing number of biological scientists. This book provides a practical guide to making these predictions by reviewing strategies of different computer modeling algorithms and highlighting the degree of confidence attributed to them. Also in the volume are descriptions of the following: the principles of protein folding; sequence homology and motif searches; prediction of secondary structure; homology modeling; modeling of antibody combining sites; tertiary fold recognition; modeling of transmembrane proteins; ab initio prediction; protein-ligand docking simulations; and the use of molecular mechanics and dynamics. both non-specialists who require guidance to identify and evaluate appropriate strategies and experts who require a contemporary view of the field, will find this volume a worthy addition to their research libraries.
Human biochemistry --- Proteins --- Conformation --- Computer simulation. --- Protein Conformation --- Computer Simulation --- Computerized Models --- In Silico --- Computer Models --- Models, Computer --- Computer Model --- Computer Simulations --- Computerized Model --- In Silicos --- Model, Computer --- Model, Computerized --- Models, Computerized --- Silico, In --- Silicos, In --- Simulation, Computer --- Simulations, Computer --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Gene Products, Protein --- Gene Proteins --- Protein --- Protein Gene Products --- Proteins, Gene --- Molecular Mechanisms of Pharmacological Action --- Conformation&delete& --- Computer simulation --- PROTEINS --- LIGANDS --- MODELLING --- ANTIBODIES --- MEMBRANES --- MOLECULAR BIOLOGY --- STRUCTURAL ANALYSIS --- eiwitten --- aminozuursequenties --- amino acid sequences --- nucleotidenvolgordes --- nucleotide sequences --- databanken --- databases --- analytische methoden --- analytical methods --- Proteins and Enzymes --- Eiwitten en enzymen --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Proteins - Conformation - Computer simulation.
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Structural bioinformatics. --- Bio-informatique structurale --- Structural bioinformatics --- Computational Biology --- Protein Conformation --- Models, Molecular --- Molecular Models --- Model, Molecular --- Molecular Model --- Molecular Conformation --- Molecular Structure --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Proteins --- Protein Folding --- Bio-Informatics --- Biology, Computational --- Computational Molecular Biology --- Bioinformatics --- Molecular Biology, Computational --- Bio Informatics --- Bio-Informatic --- Bioinformatic --- Biologies, Computational Molecular --- Biology, Computational Molecular --- Computational Molecular Biologies --- Molecular Biologies, Computational --- Computational Chemistry --- Genomics --- Structure bioinformatics --- Molecular structure
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Biological techniques --- Biochemical engineering --- Molecular biology --- General microbiology --- Protein engineering --- Genetic Engineering --- Protein Conformation --- Proteins --- genetics --- Biotechnology --- Genetic Engineering. --- Protein Conformation. --- Technologie des protéines --- Protein engineering. --- 35.62 amino-acids, peptides and proteins --- 42.13 molecular biology --- 58.31 technical microbiology --- 35.75 proteins, nucleic acids --- genetics. --- Biotechnology. --- Protein Engineering, --- Genetic Engineering, --- Protein Conformation, --- Proteins, --- Chemistry. --- Biochemistry, --- Biomedical Engineering, --- Nutrition and Dietetics, --- Biology. --- Genetics, --- Engineering. --- Health Sciences. --- Life Sciences. --- 35.62 amino-acids, peptides and proteins. --- 42.13 molecular biology. --- 58.31 technical microbiology. --- 35.75 proteins, nucleic acids. --- Genetic engineering. --- Génie génétique. --- Protéines --- Conformation.
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