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Cancer --- Chemotherapy --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors

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Gastrointestinal system --- Cancer --- Cancer. --- Gastro-intestinal system --- Gastrointestinal tract --- GI tract --- Tract, Gastrointestinal --- Tract, GI --- Gastrointestinal Neoplasms --- Cancer of Gastrointestinal Tract --- Cancer of the Gastrointestinal Tract --- Neoplasms, Gastrointestinal --- Gastrointestinal Cancer --- Cancer, Gastrointestinal --- Cancers, Gastrointestinal --- Gastrointestinal Cancers --- Gastrointestinal Neoplasm --- Gastrointestinal Tract Cancer --- Gastrointestinal Tract Cancers --- Neoplasm, Gastrointestinal --- Alimentary canal --- Digestive organs --- Oncology --- Gastrointestinal Neoplasms.

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Prostate cancer accounts for nearly a quarter of all male cancers, and the incidence is rising as detection rates continue to improve, and life expectancy increases. Timely intervention affords a wider range of management options and in this new volume the editors review the choices available. In the first section lifestyle interventions, such as nutrition and screening, and evaluation of risk factors are discussed; then follows an update on management strategies for localised and locally advanced cancer in various risk groups, drawing on the results of the latest clinical trials. The third se

Prostate -- Cancer -- Treatment. --- Prostate -- Cancer. --- Prostatectomy. --- Radiotherapy. --- Genital Neoplasms, Male --- Prostatic Diseases --- Urogenital Neoplasms --- Genital Diseases, Male --- Neoplasms by Site --- Male Urogenital Diseases --- Diseases --- Neoplasms --- Prostatic Neoplasms --- Cancer of the Prostate --- Neoplasms, Prostate --- Neoplasms, Prostatic --- Prostate Neoplasms --- Prostatic Cancer --- Cancer of Prostate --- Prostate Cancer --- Cancer, Prostate --- Cancer, Prostatic --- Cancers, Prostate --- Cancers, Prostatic --- Neoplasm, Prostate --- Neoplasm, Prostatic --- Prostate Cancers --- Prostate Neoplasm --- Prostatic Cancers --- Prostatic Neoplasm --- Benign Neoplasms --- Malignancy --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Neoplasias --- Neoplasm, Benign --- Tumor --- Male Genitourinary Diseases --- Genitourinary Disease, Male --- Genitourinary Diseases, Male --- Male Genitourinary Disease --- Male Urogenital Disease --- Urogenital Disease, Male --- Urogenital Diseases, Male --- Neoplasms by Sites --- Site, Neoplasm --- Sites, Neoplasm --- Neoplasm Site --- Neoplasm Sites --- Male Genital Diseases --- Disease, Male Genital --- Diseases, Male Genital --- Genital Disease, Male --- Male Genital Disease --- Genito-urinary Cancer --- Genito-urinary Neoplasm --- Neoplasms, Genitourinary --- Neoplasms, Urogenital --- Genitourinary Cancer --- Genitourinary Neoplasms --- Urogenital Cancer --- Cancer, Genito-urinary --- Cancer, Genitourinary --- Cancer, Urogenital --- Cancers, Genito-urinary --- Cancers, Genitourinary --- Cancers, Urogenital --- Genito urinary Cancer --- Genito-urinary Cancers --- Genito-urinary Neoplasms --- Genitourinary Cancers --- Genitourinary Neoplasm --- Neoplasm, Genito-urinary --- Neoplasm, Genitourinary --- Neoplasm, Urogenital --- Neoplasms, Genito-urinary --- Urogenital Cancers --- Urogenital Neoplasm --- Disease, Prostatic --- Diseases, Prostatic --- Prostatic Disease --- Neoplasms, Male Genital --- Male Genital Neoplasms --- Genital Neoplasm, Male --- Male Genital Neoplasm --- Neoplasm, Male Genital --- Prostatic Hyperplasia --- Prostate-Specific Antigen --- Malignant Neoplasms --- Malignant Neoplasm --- Neoplasm, Malignant --- Neoplasms, Malignant --- Medical Oncology

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A thorough yet concise account of cancer biology, this book emphasises the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism.

Cancer. --- Carcinogenesis. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cancer --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Pathology --- Genetic toxicology --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Pathogenesis

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Sequencing of the human genome and insights into signaling pathways have contributed to the understanding of cancer etiology and the development of new, improved cancer drugs. DNA mutations of a limited set of genes are responsible for the multiple stages of tumorigenesis and metastasis. Matching of therapeutic intervention with insights into the underlying molecular disease mechanism has led to the development of drugs such as Herceptin and Glivec. The deregulation of pathways due to mutated cancer genes provides the conceptual basis for future progress. Will it be possible to extrapolate this principle and derive more efficient drugs targeting cancer pathway components? Potential drug targets have been identified, but our ability to predict the consequences of inhibition of such components is still limited. The state of development of tomorrow’s cancer drugs, directed against growth factors, growth factor receptors and intracellular signaling molecules with kinase activities, is described in this book.

Cancer --- Chemotherapy. --- Gene therapy. --- Antineoplastic agents --- Genetic aspects --- Treatment --- Oncology. --- Oncology  . --- Medicine. --- Cancer Research. --- Molecular Medicine. --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Cancer research. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cancer research --- Cancer. --- Medicine --- Biology --- Cancer Biology. --- Biomedical Research. --- Research. --- Biological research --- Biomedical research --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors