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Évolution (biologie) --- Biologie moléculaire --- Génétique moléculaire --- Molecular evolution. --- Evolution --- Molecular Biology. --- Genetics, Population. --- Molecular Biology --- Evolution chimique --- Molecular evolution --- 575.852 --- Biochemical evolution --- Chemical evolution --- Life --- Molecular biology --- 575.852 Biomacromolecules. Molecular evolution --- Biomacromolecules. Molecular evolution --- Origin --- Biologie moléculaire. --- Génétique moléculaire.

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Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.

Molecular evolution.

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This book, written by Motoo Kimura (1924–94), is a classic in evolutionary biology. In 1968, Kimura proposed the “neutral theory of molecular evolution”, which became the theoretical basis of modern evolutionary studies. After publishing his work in 1983 in the book “Neutral Theory of Molecular Evolution”, Kimura wrote this book in 1988 for the general public. It was originally written in Japanese and is translated here for the first time. In the book, Kimura first summarizes the development of evolutionary theory since Lamarck and Darwin. He then shows how the search for mechanisms of evolution developed into population genetics and describes how the study of molecular evolution matured by taking in the fruits of molecular biology. Kimura proceeds to carefully explain his neutral evolution theory at the molecular level. Finally, he presents his view of the world from an evolutionary perspective. The book has long served as an in-depth introduction to evolutionary biology for students and young researchers in Japan. There has been remarkably rapid progress in the field of bioscience at the molecular level over the past 30 years. Nevertheless, the book remains an important contribution that laid the foundations for what followed in molecular evolutionary studies.

Evolution. Phylogeny --- Biology --- biologie --- Europees recht

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To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations.R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution.For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.

Population genetics --- Mathematical models. --- F-statistics. --- G-C content. --- K distribution. --- Malthusian parameter. --- Ordovician. --- adaptive surface. --- apparent. --- breeding structure. --- chromosomal variation. --- darwin. --- evolutionary rates. --- fossils, living. --- insulins. --- lethal equivalent. --- linkage disequilibrium. --- mutation, advantageous. --- natural selection. --- quasi-equilibrium surface. --- rate of. --- selection. --- selective values. --- steady flux equation. --- viability polygenes.

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Molecular genetics --- Evolution --- Molecular biology