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Apoptosis
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ISSN: 00766879 ISBN: 0121822230 9786611011062 1281011061 0080496776 9780121822231 Year: 2000 Volume: 322 Publisher: San Diego ; London ; Sydney Academic press

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Abstract

Volume 322 of Methods in Enzymology is dedicated to apoptosis. Major topics covered include measuring apoptosis and apoptosis-induced endonucleases, measuring apoptosis in lower organisms, proteases involved in apoptosis and their inhibitors, cell free systems for monitoring steps in apoptosis pathways, mitochondria and apoptosis, bCl-2 family proteins, and studying receptors and signal transduction events implicated in cell survival and cell death.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly re

Bioprocess and algae reactor technology, apoptosis
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ISSN: 07246145 ISBN: 3540634177 9783540634171 3540695419 Year: 1997 Volume: 59 Publisher: Berlin ; Heidelberg ; New York Springer Verlag

Apoptosis
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ISSN: 07246145 ISBN: 354064153X 9783540641537 3540696946 Year: 1998 Volume: 62 Publisher: Berlin ; Heidelberg ; New York Springer Verlag

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The aim of this volume is to provide an in-depth overview of the state-of-the-art research on apoptosis with contributions from key groups working in the field. This type of programme cell death has received wide and rapid attention and now is considered as one of the hottest areas of science. The volume covers various aspects of the apoptotic death process from the morphological and biochemical features, mechanisms and genetic regulation to its role in pathological process and potential implications for biomedical research and biopharmaceutical production.

Apoptosis and its modulation by drugs
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ISBN: 3540661212 3642630251 3642570755 Year: 2000 Volume: 142 Publisher: Berlin ; Heidelberg ; New York Springer Verlag

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Abstract

Apoptosis is a fascinating concept for the basic scientist. This is not only because of the multifaceted variety of proposed and discovered mechanisms, but because apoptosis represents a fundamental pathway for cell renewal. The study of apoptosis has resulted in an array of discoveries on signal transduc­ tion and downstream effects that have facilitated and advanced many fields in biology, including research on cancer and other diseases. Thus, the apoptotic process can be viewed as the largest effort of the scientific community to understand how cells work and tissues assemble or remodel. The most direct consequence of this accumulated knowledge is a greater understanding of disease and pathological mechanisms. The end result of these efforts will be significant contributions to health and the adoption of new, never anticipated, therapeutic approaches. This book represents the summation of considerable effort from a significant group of contributors from all over the world as well as from its editors. In this fashion, many viewpoints have been collected and SUbjected to thorough academic discussion. The concepts contained in this medically important volume will stimulate and renew the ideas of scientists and indeed, will generate additional work to advance biological knowledge even further. The emphasis of this volume cements what has been established, adds what has not been explored fully, and creates a fertile ground for further hypotheses that will lead to a more complete understanding of the apoptotic process.

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