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Article
Behavioral, physiological and functional aspects of stereotyped behavior : a review and a re-interpretation.
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Year: 1986

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Environmental enrichment: effects on stereotyped behavior and dendritic morphology.
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Year: 2003

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Environmental enrichment: effects on stereotyped behavior and neurotrophin levels.
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Year: 2003

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Stereotyped behavior by horses.
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Year: 1985

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Environmental enrichment: effects on stereotyped behavior and regional neuronal metabolic activity.
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Year: 2002

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The effect of haloperidol on the performance of stereotyped behavior in sows.
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Year: 2000

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Chronic stress enhances apomorphine-induced stereotyped behavior in mice : involvement of endogenous opioids.
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Year: 1984

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The psychology of perseverative and stereotyped behavior.
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Year: 1994

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Environmental enrichment: effects on stereotyped behavior and neurotrophin levels.
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Year: 2003

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The present study evaluated whether environmental enrichment-related effects on the development of stereotyped behavior in deer mice were associated with alterations in neurotrophin levels. Deer mice were reared in enriched or standard cage conditions for 60 days. The mice were then tested in automated photocell detectors and classified as either stereotypic or nonstereotypic. This testing paradigm yielded four behaviorally distinct groups: enriched stereotypic, enriched nonstereotypic, standard cage stereotypic, and standard cage nonstereotypic. The motor cortex, striatum, and hippocampus were dissected, and the levels of brain-derived neurotrophin factor (BDNF) and nerve growth factor (NGF) in each brain region were analyzed using Promega ELISA kits. There were no differences in either NGF or BDNF in either the motor cortex or the hippocampus. In the striatum, the enriched nonstereotypic mice exhibited significantly more BDNF than the enriched stereotypic, the standard cage nonstereotypic, or the standard cage stereotypic mice. There were no differences in NGF in the striatum. These results provide evidence that the enrichment-related prevention of stereotyped behavior in deer mice is associated with increased BDNF in the striatum


Article
Responses to apomorphine of pigs with different coping characteristics.

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Rationale: Classification of pigs based on the degree of resistance they display in a so-called "backtest" seems, to a certain extent, predictive for their coping strategy. Objective: The present study examined whether, as found in rodents, the behavioral response to apomorphine of pigs relates to individual coping characteristics. Methods: During the suckling period pigs were subjected to the backtest. In this test, each pig is restrained on its back for I min and the resistance (i.e. number of escape attempts) is scored. Pigs classified as low-resisting (LR, n=10) or high-resisting (HR, n=10) were selected. At 17-18 weeks of age they received a saline and an apomorphine injection (0.2 mg/kg SC) on 2 consecutive days in a balanced design. Behavior was recorded until 120 min after injection. Results: Apomorphine increased locomotion in all pigs and reduced standing, standing alert and defecating. In addition, apomorphine induced the occurrence of some peculiar activities, rarely seen in saline-treated pigs, which seemed to represent either a transition between different postures or a conflict between hind- and forelimb activities. Apomorphine-treated LR pigs performed significantly more of these activities than HR pigs, However, snout contact with the floor, an oral stereotypy, was significantly increased in apomorphine-treated HR pigs, but not in apomorphine-treated LR pigs. Conclusions: Tn conclusion, the response to apomorphine or pigs relates to their behavioral response, high-resisting (HR) versus low-resisting (LR), in the backtest. The contrasts in behavioral response to apomorphine suggest a difference in the dopaminergic system between HR and LR pigs

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