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Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. - Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies - Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring - Chapters are replete with clinical examples to empower the basic biology with translational significance - Offers more than 100 illustrations to distill key concepts and decipher complex science.

Epigenetics. --- Gene expression. --- Genetic regulation.

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The study of transcriptomics is key to understanding complex diseases. This new edition will build on the foundation of the first edition while incorporating the progress that has been made in the field of transcriptomics in the past six years, including bioinformatics for data analysis. Written by leading experts, chapters address new subjects such as methodological advances in large-scale sequencing, the sequencing of single-cells, and spatial transcriptomics. The new edition will address how transcriptomics may be used in combination with genetic strategies to identify causative genes in monogenic and complex genetic diseases. Coverage will also explore transcriptomics in challenging groups of diseases, such as cancer, inflammation, bacterial infection, and autoimmune diseases. The updated volume will be useful for geneticists, genome biologists, biomedical researchers, molecular biologists, bioinformaticians, and students, among others.

Biomathematics. Biometry. Biostatistics --- Genetics --- Molecular biology --- bio-informatica --- genetica --- moleculaire biologie --- Gene expression. --- RNA --- Genètica mèdica

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This book provides students and researchers in plant sciences with a concise general account of plant biochemistry. The edited format allows recognized experts in plant biochemistry to contribute chapters on their special topics. Up-to-date surveys are divided into four sections: the cell, primary metabolism, special metabolism, and the plant and the environment. There is a strong emphasis on plant metabolism as well as enzymological, methodological, molecular, biological, functional, and regulatory aspects of plant biochemistry. Illustrations of metabolic pathways are used extensively, and fu

Botanical chemistry --- PLANTS --- PLANT BIOCHEMISTRY --- METABOLIC PROCESSES --- METABOLISM --- plantensamenstelling --- plant composition --- plantenfysiologie --- plant physiology --- plantkunde --- botany --- genetische modificatie --- genetic engineering --- recombinant dna --- fotosynthese --- photosynthesis --- Plant Biochemistry, Phytochemistry --- Plantenbiochemie, fytochemie --- Botanical chemistry. --- Plants --- Metabolism. --- PLANT CELLS --- PHOTOSYNTHESIS --- NUCLEIC ACIDS --- PROTEINS --- PHENOLIC COMPOUNDS --- ISOPRENOIDS --- PLANT PATHOLOGY --- PLANT ECOLOGY --- REVIEWS --- MOLECULAR BIOLOGY --- CARBOHYDRATE METABOLISM --- LIPID METABOLISM --- NITROGEN METABOLISM --- GENE EXPRESSION --- GENETIC REGULATION --- BIOCHEMISTRY --- BIOTECHNOLOGY