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Mineralen --- Mineralogie

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MicroRNA (miRNA) is a cutting-edge topic in the scientific and medical fields. This is a timely and specialized book focusing on the current understanding of miRNAs and the potential for their application in cancer diagnosis, prognosis, and therapeutic targets. It also provides discussion of the lessons learned from translational miRNA studies and exploration of the next steps required to advance this field. The unique book comprises 22 in-depth chapters by gathering unparalleled topics of interest in miRNAs by international team of world-renowned experts in the field. The first fifteen chapters provide comprehensive and expert perspectives on the most common cancers from bench to bedside applications, there is no current book structured in this cancer-oriented way. The next seven chapters providing thorough overviews of miRNAs and cancer stem cells; miRNAs in cancer invasion and metastasis; miRNAs in predicting radiotherapy and chemotherapy response; as well as expounding the role of miRNA in anti-cancer drug resistance and as blood-based cancer biomarkers. Furthermore, this book explicates the interplay of miRNAs in cancer metabolism and an update on the pioneering RNAi-based treatment approaches is also presented. This specialized book will contribute great to the scientific and medical community by providing the up-to-date discoveries of miRNAs and their important roles in cancer translational research.

Human biochemistry --- Oncology. Neoplasms --- Human genetics --- medische biochemie --- medische genetica --- biochemie --- genetica --- oncologie

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Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. There have been a number of publications on materia medica for various cancers in recent years, the scientific and medical community are thrust for up-to-date information that are supported by concrete laboratory evidences or clinical trials. This volume is a specialised book presenting the experimental and clinical evidences of anticancer materia medica for various cancers. This book consists of sixteen chapters, providing concise reviews and expert opinions on the recent progress of materia medica research in fourteen particular cancers from bench to bedside application. In addition, the book also includes a chapter with an overview of evidence-based materia medica for cancer chemoprevention, as well as a chapter discussing on the pharmacokinetics of anticancer materia medica. Gathering international opinion leaders' views, this volume will contribute great to the cancer, academic, and clinical community by providing evidence-based information on the anticancer effects of materia medica for various cancers. Readership Oncologists, cancer researchers, pharmacologists, pharmaceutical specialists, Chinese medicine practitioners, medical educators, postgraduates and advanced undergraduates in biomedical disciplines, cancer caregivers, cancer patients.

Human biochemistry --- Hygiene. Public health. Protection --- Physiotherapy. Alternative treatments --- Oncology. Neoplasms --- medische biochemie --- farmacologie --- biochemie --- gezondheidszorg --- oncologie --- acupunctuur --- alternatieve geneeswijzen

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The Minimum Message Length (MML) Principle is an information-theoretic approach to induction, hypothesis testing, model selection, and statistical inference. MML, which provides a formal specification for the implementation of Occam's Razor, asserts that the ˜best' explanation of observed data is the shortest. Further, an explanation is acceptable (i.e. the induction is justified) only if the explanation is shorter than the original data. This book gives a sound introduction to the Minimum Message Length Principle and its applications, provides the theoretical arguments for the adoption of the principle, and shows the development of certain approximations that assist its practical application. MML appears also to provide both a normative and a descriptive basis for inductive reasoning generally, and scientific induction in particular. The book describes this basis and aims to show its relevance to the Philosophy of Science. Statistical and Inductive Inference by Minimum Message Length will be of special interest to graduate students and researchers in Machine Learning and Data Mining, scientists and analysts in various disciplines wishing to make use of computer techniques for hypothesis discovery, statisticians and econometricians interested in the underlying theory of their discipline, and persons interested in the Philosophy of Science. The book could also be used in a graduate-level course in Machine Learning and Estimation and Model-selection, Econometrics and Data Mining. C.S. Wallace was appointed Foundation Chair of Computer Science at Monash University in 1968, at the age of 35, where he worked until his death in 2004. He received an ACM Fellowship in 1995, and was appointed Professor Emeritus in 1996. Professor Wallace made numerous significant contributions to diverse areas of Computer Science, such as Computer Architecture, Simulation and Machine Learning. His final research focused primarily on the Minimum Message Length Principle.

Statistical science --- Ergodic theory. Information theory --- Operational research. Game theory --- Artificial intelligence. Robotics. Simulation. Graphics --- coderen --- stochastische analyse --- informatietechnologie --- robots --- informatietheorie --- statistisch onderzoek

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Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics. This is the first book to provide such a comprehensive coverage of a rapidly evolving area written by leading experts in the field of omics. It complies and details cutting-edge cancer research that covers the broad advances in the field and its application from cancer-associated gene discovery to drug target validation. It also highlights the potential of using integration approach for cancer research. This unique and timely book provides a thorough overview of developing omics, which will appeal to anyone involved in cancer research. It will be a useful reference book for graduate students of different subjects (medicine, biology, engineering, etc) and senior scientists interested in the fascinating area of advanced technologies in cancer research. Readership: This is a precious book for all types of readers - cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, pharmaceutical specialists, biostatisticians, and bioinformaticists who want to expand their knowledge in cancer research.

Genetics --- Human biochemistry --- Oncology. Neoplasms --- Human genetics --- Human medicine --- medische biochemie --- medische genetica --- proteomics --- geneeskunde --- genetica --- oncologie --- proteïnen