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Book
Pediatric Liver Tumors
Authors: --- ---
ISBN: 9783642145049 9783642145032 Year: 2011 Publisher: Berlin, Heidelberg Springer Berlin Heidelberg

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Abstract

The field of liver tumors in children, and in particular hepatoblastoma in infants and young children, has seen tremendous therapeutic advances over recent years. This has been achieved through a much better understanding of the biology of disease, improved diagnostic procedures, refined methods of pretreatment tumor staging, the implementation of highly efficient chemotherapy and surgery, detailed monitoring of toxicity, and careful follow-up strategies. International controlled trials have played a key role in these advances, and many leading figures in the trials are among the editors and authors of this book. Their principal goal in Hepatic Tumors in Children is to provide the reader with a complete update on this complex and rapidly evolving field. All aspects of an impressive success story are covered, disclosing how the outcome of a previously devastating disease has been so dramatically improved. This book will prove essential reading for all who are involved in the care of children with liver tumors.


Book
Hepatology Textbook and Atlas
Authors: --- ---
ISBN: 9783540768395 3540768386 9783540768388 9786612038181 1282038184 3540768394 Year: 2008 Publisher: Berlin, Heidelberg Springer Berlin Heidelberg

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Instructive – Attractive – Unique Textbook - Completely revised, updated and enlarged - Close and continuous relation between pathomorphology, function and clinic - Further improvements in content, systematology, didactics and colour design - Numerous, sometimes unusual, but clinically proved suggestions ("tips and tricks") resulting from the author’s practical experience Atlas - A total number of 530 figures in colour and 320 tables in colour - an hepatological atlas which is unique in form, extent and presentation Manual - About 7,000 quoted publications - Some 1,500 cited first-descriptors of therapy procedures, methods, medical techniques and invasive measures - A comprehensive index containing more than 3,000 terms and about 12,000 cited reference pages - Register of abbreviations + ALL figures and tables on CD-ROM This textbook is escorted along its way by a foreword from: - Ch. S. Lieber (New York, USA) - 1st edition - A. M. Hofmann (La Jolla, USA) - 2nd edition - U. M. Leuschner (Frankfurt, Germany) ) - 2nd edition - H. Denk (Graz, Austria) - 3rd edition "The current edition contains up-to-date information, but also stands for tradition and progress in hepatology. The reader is carefully introduced into the subject matter and learns to experience and understand everything to the full extent. It is only possible to impart knowledge and to convey enthusiasm if one has great personal involvement. This certainly applies to the author, Erwin Kuntz." O. Univ. Prof. Dr. Helmut Denk, FRCPath Director of the Institute of Pathology University of Graz (Austria).


Book
Vascular Liver Disease
Authors: --- ---
ISBN: 9781441983275 9781441983268 Year: 2011 Publisher: New York, NY Springer New York

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Vascular Liver Disease: Mechanisms and Management covers all of the disease entities that stem from abnormalities that affect the hepatic vasculature. This multi-authored text includes the mechanisms and management of intrahepatic vascular disease, including the most common cause of vascular disease of the liver, cirrhosis. Other less common diseases of the liver vasculature are also covered such as sinusoidal obstruction syndrome (previously known as veno-occlusive disease), portal vein thrombosis, the Budd-Chiari syndrome and congenital vascular malformations. These entities, although rare, are a challenge to physicians and physician scientists. Although many textbooks have been written on the consequences of cirrhosis on the liver vasculature, this is the only volume that focuses on the liver vasculature as a separate entity, providing an innovative approach to liver disease management. Vascular Liver Disease: Mechanisms and Management will be of great value to clinical investigators and basic scientists interested in the liver circulation as well as clinical gastroenterologists and hepatologists, hepatobiliary surgeons and transplant surgeons, and to interventional radiologists with a particular interest in the liver.

Cholestatic liver disease
Authors: ---
ISBN: 9781597451185 1588298388 9781588298386 9786612824265 1597451185 1282824260 Year: 2008 Publisher: Totowa, N.J. : Paisley : Humana ; Quantum [distributor],

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Over the past 2 decades, there has been a steady increase in knowledge associated with the clinical manifestations of cholestatic liver disease. In addition to a growing amount of information on the well-studied disorders of primary biliary cirrhosis and primary sclerosing cholangitis, there has been a rapid accumulation of data on less well-known but important topics such as overlap syndromes with autoimmune hepatitis, cholestatic variants of alcohol and viral disease, and cholestasis following liver transplantation. These emerging insights are complemented by further improvements of the diagnosis and management of cholestasis. Based on these clinical situations, Cholestatic Liver Disease provides essential information for individuals involved in the care of patients affected by cholestatic liver disease. This groundbreaking text also supplies scientific updates from leading experts which relate to the clinical evaluation and management of cholestatic liver disorders, useful for both novice and practitioners alike. Among the topics discussed in this volume are PBC, PSC, overlap syndrome with autoimmune hepatits, sarcoid, lymphoma, cystic fibrosis, rheumatologic disease, and osteoporosis. Comprehensive and timely, Cholestatic Liver Disease is sure to be an indispensable reference for all those who work with cholestatic liver.


Book
Leverziekten
Authors: --- ---
ISBN: 9789031374366 9789031374373 Year: 2009 Publisher: Houten Bohn Stafleu Van Loghum

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In de afgelopen jaren is veel onderzoek verricht binnen de hepatologie. Dit heeft geleid tot revolutionaire veranderingen waardoor de diagnostiek van leverziekten aanzienlijk is verbeterd. Ook de progressie die is geboekt in de behandeling van leverziekten is enorm. Deze grote en recente vooruitgang op diagnostisch en therapeutisch gebied maakt de behoefte aan een goede, actuele leidraad voor de klinische praktijk noodzakelijk.In Leverziekten zijn de ontwikkelingen van de afgelopen jaren samengebracht. Naast algemene hoofdstukken als anatomie, histologie, functies en onderzoeksmethoden worden diagnostiek en behandeling van alle veelvoorkomende leveraandoeningen beschreven, en tevens van de meer zeldzame aandoeningen. In afzonderlijke hoofdstukken wordt aandacht besteed aan voeding en leverziekten, zwangerschap, levertransplantatie en operatierisico's bij leverziekten. Leverziekten biedt een overzicht van de volle breedte waarin het vak binnen het Nederlandse taalgebied wordt uitgeoefend en slaat een brug tussen enerzijds het basaal en klinisch leveronderzoek en anderzijds het klinisch handelen.Leverziekten is rijk geïllustreerd met meer dan 90 figuren, waaronder anatomische illustraties van Maartje Kunen.Leverziekten is samengesteld door vele specialisten uit Nederland en Vlaanderen. Zij bieden hiermee studenten geneeskunde, assistenten in opleiding en fellows een onmisbaar, rijk geïllustreerd overzichtwerk om wegwijs te raken in de wereld van de leverziekten. Daarnaast helpt het maag-darm-leverartsen, internisten, huisartsen en andere medische professionals bij het oplossen van hepatologische problemen.


Book
Liver Radioembolization with 90Y Microspheres
Authors: --- ---
ISBN: 9783540354239 3540354212 9783540354215 9786612509100 1282509101 3540354239 Year: 2008 Publisher: Berlin, Heidelberg Springer-Verlag Berlin Heidelberg

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This book provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. In the past, the therapeutic radiation dose needed to treat a tumoral area has been sufficiently high to produce permanent damage to the nontumoral liver parenchyma. Radioembolization attempts to overcome this problem by combining embolization (intravascular deployment of particles) and brachytherapy (local administration of radiotherapy with the aid of a device, namely the particles themselves). The technique is based on improvements in percutaneous endovascular procedures which have allowed the deployment of small (25-35 µm) microspheres loaded with yttrium-90 that deliver high doses of beta-radiation specifically to the tumoral area. Performance of the procedure demands close familiarity with the hepatic vascular anatomy in order to ensure avoidance of vessels going to other territories. Furthermore, detailed knowledge of liver function, tumor volume, and liver vascular shunting is needed in order to calculate the appropriate therapeutic dose in each particular case. All of these topics are addressed in depth in this book, and initial clinical results are presented, showing that constant local control can be achieved with a reasonably low rate of complications. These promising results may lead to a progressive change in the therapeutic indication for radioembolization, and in some cases it could even become the therapy of choice.

Keywords

Medicine & Public Health. --- Imaging / Radiology. --- Interventional Radiology. --- Nuclear Medicine. --- Hepatology. --- Oncology. --- Radiotherapy. --- Medicine. --- Medical radiology --- Interventional radiology. --- Nuclear medicine. --- Clinical medicine. --- Médecine --- Radiologie médicale --- Radiologie interventionnelle --- Médecine nucléaire --- Radiothérapie --- Médecine clinique --- Cancérologie --- Brachytherapy -- Methods. --- Embolization, Therapeutic -- Methods. --- Liver -- Cancer -- Treatment. --- Liver Neoplasms -- Radiotherapy. --- Radioisotope brachytherapy. --- Therapeutic embolization. --- Brachytherapy --- Liver Neoplasms --- Embolization, Therapeutic --- Digestive System Neoplasms --- Radiotherapy --- Hemostatic Techniques --- Liver Diseases --- Digestive System Diseases --- Neoplasms by Site --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms --- Radiology, MRI, Ultrasonography & Medical Physics --- Oncology --- Medicine --- Health & Biological Sciences --- Liver --- Cancer --- Treatment. --- Embolotherapy --- Afterloading radiotherapy --- Brachyisotope therapy --- Brachytherapy, Radioisotope --- Implant radiotherapy --- Interstitial radiotherapy --- Radiology. --- Hemostasis, Surgical --- Interventional radiology --- Implants, Artificial --- Radioisotopes --- Therapeutic use --- Radiology, Medical. --- Oncology  . --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Therapeutics, Physiological --- Phototherapy --- Tumors --- Medicine, Clinical --- Atomic medicine --- Radioisotopes in medicine --- Radioactive tracers --- Radioactivity --- Radiology, Interventional --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological services --- Physiological effect --- Interventional radiology . --- Gastroenterology --- Radiological physics --- Physics --- Radiation


Book
Chronic Hepatitis C Virus
Authors: ---
ISBN: 9781461411925 9781461411918 Year: 2012 Publisher: New York, NY Springer New York

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Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

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