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Recent scientific advances have made it possible to produce biopharmaceuticals in genetically modified plants and animals, such as maize, tobacco, goats, and chickens. This new branch of biotechnology is termed pharming, composed of the terms pharmaceuticals and farming. Pharming constitutes an overlap of red and green biotechnology. It offers the prospect of a quicker, cheaper, and more flexible production of biopharmaceuticals compared with current production processes. This is a promising perspective in light of the rapidly growing market of biopharmaceuticals, although the economic competitiveness of pharming remains to be proven. Besides possible benefits for producers, patients and health care systems, pharming also raises a number of complex ecological, social, moral and legal questions that have as yet not been thoroughly discussed. The present book contains the findings of an interdisciplinary research project that has addressed a large range of questions associated with pharming: An analysis of the state-of-the-art of plant pharming and animal pharming technologies is followed by an assessment of environmental risks related to pharming and welfare risks for pharming animals. Public views and attitudes to pharming are investigated on the basis of a comprehensive survey in 15 countries. Moreover, ethical and legal questions, posed by present and foreseeable future practices of pharming, are analysed. The concluding chapter presents the authors' main findings and recommendations, addressed to science, industry, politics and general public interested in the chances and risks of this upcoming field of biotechnology.
General ethics --- Human biochemistry --- Pharmacology. Therapy --- Biochemical engineering --- medische biochemie --- bio-engineering --- farmacie --- farmacologie --- biogeneesmiddelen --- biochemie --- ethiek --- toxicologie --- Biopharmaceutics --- Genetic engineering --- Pharmaceutical biotechnology --- Biopharmaceutical technology --- Drugs --- Biotechnology --- Pharmaceutical technology --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Transgenic organisms --- Pharmacology --- Pharmacy
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Biopharmaceutical Drug Design and Development, Second Edition, updates the widely successful first edition, published in 1999. This new, expanded edition investigates the dozens of new biopharmaceutical drugs that have become available since the publication of the first edition. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, such as bioinformatics, DNA microarrays, transgenics, therapeutic gene delivery, stem cells, nucleic acid-based therapeutics, and macromolecular drug delivery. Authors also study pharmacogenetics in the clinic and changes in biologic drug approval at the FDA. Biopharmaceutical Drug Design and Development, Second Edition, is a worthy sequel in the discussion on the dynamic, exciting field of biotechnology.
Biomedicine. --- Pharmacology/Toxicology. --- Cell Biology. --- Biochemistry, general. --- Pharmacy. --- Medicine. --- Toxicology. --- Biochemistry. --- Cytology. --- Médecine --- Toxicologie --- Pharmacie --- Biochimie --- Cytologie --- Drug development. --- Drugs -- Design. --- Pharmaceutical biotechnology. --- Pharmaceutical biotechnology --- Drugs --- Drug development --- Technology, Pharmaceutical --- Biopharmaceutics --- Drug Design --- Investigative Techniques --- Drug Discovery --- Pharmacology --- Pharmacy --- Technology --- Technology, Industry, and Agriculture --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemistry, Pharmaceutical --- Health Occupations --- Biological Science Disciplines --- Chemistry --- Disciplines and Occupations --- Natural Science Disciplines --- Technology, Industry, Agriculture --- Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Design --- Design. --- Development of drugs --- New drug development --- Drug design --- Pharmaceutical design --- Biopharmaceutical technology --- Development --- Biotechnology --- Pharmacology. --- Cell biology. --- Pharmaceutical technology --- Medicine --- Materia medica --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Chemicals --- Poisoning --- Poisons --- Composition --- Toxicology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Physiological effect
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