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The Golgi apparatus is more than 110 years in the center of interest and scientific debates. This book summarizes the data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy collecting a range of expertise, different points of view and different approaches.

Life Sciences. --- Cell Biology. --- Life sciences. --- Cytology. --- Sciences de la vie --- Cytologie --- Golgi Apparatus. --- Golgi-complex. --- Plant molecular biology. --- Golgi apparatus --- Organelles --- Cytoplasmic Structures --- Cytoplasm --- Intracellular Space --- Cellular Structures --- Cells --- Anatomy --- Golgi Apparatus --- Biology --- Health & Biological Sciences --- Cytology --- Golgi apparatus. --- Golgi bodies --- Golgi elements --- Golgi material --- Cell biology. --- Cell organelles --- Protoplasm --- Cell biology --- Cellular biology --- Cytologists

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This authoritative book offers a detailed overview of present and future tissue engineering approaches and their contribution to regenerative medicine. It combines comprehensive reviews of the biology and materials science underlying the development and regeneration of different types of tissues with descriptions of current and future strategies in regenerative medicine to meet clinical needs. Each chapter includes typical examples of methodologies and technical solutions as the basis for the most recent scientific findings and biomedical products, tables as mini-databases summarizing the most recent findings, and links to specific websites in the main body of the text to complement a traditional reference list. Strategies in Regenerative Medicine: Integrating Biology with Materials Design covers topics from basic biology and materials science to the link between biological processes in tissue regeneration and biomedical device/tissue engineering product performance.

Evolution. Phylogeny --- Medical microbiology, virology, parasitology --- Clinical chemistry --- Biotechnology --- Biomaterials. --- Biomedical engineering. --- Cytology. --- Microbiology. --- Biomedical Engineering and Bioengineering. --- Cell Biology. --- Medical Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Cell biology --- Cellular biology --- Cells --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Biocompatible materials --- Biomaterials --- Medical materials --- Biomedical engineering --- Materials --- Biocompatibility --- Prosthesis --- Cell biology. --- Medical microbiology. --- Bioartificial materials --- Hemocompatible materials --- Biomaterials (Biomedical materials) --- Regenerative medicine. --- Regeneration (Biology)

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Microalgae have been largely cultured and commercialized as food and feed additives, and their potential as source of high-added value compounds is well known. But, in contrast to the large number of genetically modified bacteria, yeast and even higher plants, only a few species of microalgae have been genetically transformed with efficiency. Initial difficulties in the expression of foreign genes in microalgae have been progressively overcome, and powerful molecular tools for their genetic engineering are now on hand. A considerable collection of promoters and selectable marker genes and an increasing number of genomic or cDNA sequences have become available in recent years. More work is needed to transform new species of microalgae, specially those that have commercial value, so that it would be possible to increase the productivity of traditional compounds or synthesize novel ones. Silencing transgenes remains as an important limitation for stable expression of foreign genes. This problem is not unique to microalgae since it has also been observed in plants, animals and fungi. A better understanding of the mechanisms that control the regulation of gene expression in eukaryotes is therefore needed. In this book a group of outstanding researchers working on different areas of microalgae biotechnology offer a global vision of the genetic manipulation of microalgae and their applications.

Algae --- Biological Factors --- Bioreactors. --- Biotechnology --- Genetic transformation. --- Microalgae --- Transformation, Genetic. --- physiology. --- biosynthesis. --- methods. --- Biotechnology. --- Physiology. --- Plant science. --- Botany. --- Cell biology. --- Microbial ecology. --- Plant Sciences. --- Cell Biology. --- Microbial Ecology. --- Environmental microbiology --- Microorganisms --- Ecology --- Microbiology --- Botanical science --- Floristic botany --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Biology --- Natural history --- Plants --- Cell biology --- Cellular biology --- Cells --- Physiology

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Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provides a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The second volume, Cancer Treatment and Therapy, is divided into three parts. Part I examines transforming growth factor-ß in developing and advanced cancers. Part II details transforming growth factor-ß in cancer treatment and therapy. Part III includes an investigation into the development of inhibitors of transforming growth factor-ß signaling for therapy. This volume’s companion, Basic and Clinical Biology, examines transforming growth factor-ß signaling in normal physiology, cancer pathobiology, normal and tumor biology, and inflammation and fibrosis. Together, Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide researchers and clinicians with a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor-ß in biology and cancer treatment.

Medicine & Public Health. --- Oncology. --- Cancer Research. --- Cell Biology. --- Pathology. --- Medicine. --- Cytology. --- Médecine --- Cancérologie --- Pathologie --- Cytologie --- Carcinogenesis. --- Transforming growth factors-beta. --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Beta transforming growth factors --- TGF-beta (Peptide) --- Transforming growth factor beta --- Pathogenesis --- Cancer research. --- Cell biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Tumors --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Genetic toxicology --- Transforming growth factors --- Oncology  .

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All living organisms are in a constant battle against their environment. Since uncontained microorganisms would simply overgrow all higher animals, the evolution of multicellular organisms required adequate and efficient defense mechanisms to protect their own integrity and to ensure their own survival. These defense mechanisms, encompassing receptor proteins that sense the presence of pathogens and effector molecules that are involved in controlling them, are the elemental parts of the innate immune system. For many species, the innate immune system is the sole active defense system. Long thought to be an unspecific immune response, the discovery of the Toll-like receptors and their ligands finally revealed just how specific the innate immune response actually is. This book wants to give an overview of our current knowledge about the innate immune system of plants, animals and humans. It not only covers the innate immune mechanisms and responses of so diverse organisms such as plants, Cnidaria, Drosophila, urochordates and zebrafish, but also the major receptor systems in mammalians and humans as well as the central defense mechanisms, antimicrobial peptides and the complement system.

Immunity. --- Natural immunity. --- Disease resistance --- Host resistance --- Innate immunity --- Innate resistance --- Native immunity --- Natural resistance --- Nonspecific immunity --- Resistance to disease --- Immunity --- Immunology --- Immune System. --- Immunity, Cellular. --- Immunity, Innate. --- Immunity, Natural. --- Cytology. --- Immunology. --- Biochemistry. --- Developmental biology. --- Cell Biology. --- Biochemistry, general. --- Developmental Biology. --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Immunobiology --- Life sciences --- Serology --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Composition --- Cell biology. --- Invertebrates --- Plants --- Mammals --- immunology