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This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technology development are presented. The work establishes in-cell NMR spectroscopy as the premier method for determining the structures and interaction capabilities of biological molecules at high resolution within the delicately intricate interior of living cells, and the means of utilizing cells as living laboratories to directly assess the effects of exogenous and endogenous stimuli on cell physiology.]

protein NMR --- time-resolved NMR --- Ribosome --- structural calculation 4 --- crystalline and amorphous starch --- in-cell NMR --- protein dynamics --- DNP --- protein modification --- Tau --- spectrum reconstruction 3 --- mRNA --- Thioredoxin --- protein structure --- protein interactions --- drug discovery --- protein structure determination 1 --- review --- enzyme activity --- MARK2 phosphorylation --- post-translational modifications --- Dihydrofolate reductase --- mammalian cells --- target engagement --- non-uniform sampling 2 --- paramagnetic effects --- protein structure-function --- cross-correlated relaxation --- structure function --- rRNA --- 2D INADEQUATE --- lipid membrane --- Thymidylate synthase --- whole cell NMR --- enzyme kinetics --- magic-angle spinning --- live cell --- solid-state NMR --- Adenylate kinase --- DNA --- in-situ NMR --- antimicrobial peptide --- NMR spectroscopy --- intrinsically disordered proteins

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Contamination of foods and agricultural commodities by various types of toxigenic fungi is a concerning issue for human and animal health. Moulds naturally present in foods can produce mycotoxins and contaminate foodstuffs under favourable conditions of temperature, relative humidity, pH, and nutrient availability. Mycotoxins are, in general, stable molecules that are difficult to remove from foods once they have been produced. Therefore, the prevention of mycotoxin contamination is one of the main goals of the agriculture and food industries. Chemical control or decontamination techniques may be quite efficient; however, the more sustainable and restricted use of fungicides, the lack of efficiency in some foods, and the consumer demand for chemical-residue-free foods require new approaches to control this hazard. Therefore, food safety demands continued research efforts for exploring new strategies to reduce mycotoxin contamination. This Special Issue contains original contributions and reviews that advance the knowledge about the most current promising approaches to minimize mycotoxin contamination, including biological control agents, phytochemical antifungal compounds, enzyme detoxification, and the use of novel technologies.

n/a --- decontamination --- superheated steam --- quercetin glycosides --- antagonism --- mode of action --- corn --- Botrytis sp. --- AITC --- binding --- degradation --- brine shrimp bioassay --- apple pomace --- nanoparticles --- enzymatic detoxification --- Bacillus --- estrogen response element --- Fusarium --- biological detoxification --- abiotic factors --- stability --- fumonisin esterase FumD --- mycotoxigenic fungi --- Aspergillus flavus --- Aflatoxin M1 --- Fusarium graminearum --- milk --- Penicillium digitatum --- biocontrol agents --- biological control --- dry-cured ham --- mycotoxin reduction --- Fusarium sp. --- enzyme kinetics --- Penicillium nordicum --- Satureja montana --- roasted coffee --- fermentation --- crisp biscuit --- detoxification --- essential oils --- gene expression --- probiotics --- zearalenone --- mycotoxins --- degradation products --- Geothrichum citri-aurantii --- garlic-derived extracts --- Zearalenone --- biodegradation --- EU limits --- storage --- Origanum virens --- aflatoxin --- fungal growth reduction --- green chemistry --- Penicillium italicum --- deoxynivalenol --- ?-Fe2O3 --- ochratoxin A (OTA) --- wheat --- cell-free extracts of Aspergillus oryzae --- photocatalysis --- wheat quality --- post-harvest phytopathogen --- cold plasma --- pinnatifidanoside D --- ochratoxin A --- oats --- cell proliferation --- estrogen receptor --- Penicillium verrucosum --- pig production performance --- phloridzin --- maize --- biotransformation --- fumonisin --- fungi

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The scope of this Special Issue is to collect some of the contributions to the First International Electronic Conference on Biosensors, which was held to bring together well-known experts currently working in biosensor technologies from around the globe, and to provide an online forum for presenting and discussing new results. The world of biosensors is definitively a versatile and universally applicable one, as demonstrated by the wide range of topics which were addressed at the Conference, such as: bioengineered and biomimetic receptors; microfluidics for biosensing; biosensors for emergency situations; nanotechnologies and nanomaterials for biosensors; intra- and extracellular biosensing; and advanced applications in clinical, environmental, food safety, and cultural heritage fields.

Listeria monocytogenes --- cell-based biosensor --- bioelectric recognition assay --- membrane-engineering --- lateral flow immunoassay --- antibiotics --- lincomycin --- gold nanoparticles --- quantum dots --- surface-enhanced Raman spectroscopy --- Fumonsin B1 --- aptamers --- UV/VIS spectroscopy --- asymmetric flow field-flow fractionation --- porous silicon membrane --- bacterial detection --- selective lysis --- endolysins --- lysostaphin --- flow-through --- vibrational spectra --- molecular dynamics --- nucleotides --- Au nanoparticle --- SERS --- space biology --- deep space --- biosensors --- space radiation --- microgravity --- CubeSats --- 2D Ti3C2 MXene --- PGE2 --- 8-HOA --- lung cancer --- electrochemical --- DNA biosensors --- KRAS --- liquid biopsy --- cancer point-of-care diagnostic tests --- paper-based sensors --- nitrocellulose --- impedance measurements --- dielectric properties --- parallel-plate electrodes --- interdigital electrodes --- Bacillus thuringiensis --- sensor --- combined slot antenna --- diabetes --- dielectric permeability --- electromagnetic fields --- glucose concentration --- near-field sensor --- non-invasive measurements --- microwave sounding --- chymotrypsin --- β-casein --- nanoparticles --- UV-vis spectroscopy --- dynamic light scattering --- quartz crystal microbalance --- biologically inspired --- electronic eye --- optical methods --- RGB analysis --- tequila --- molecularly imprinted polymer (MIP) --- surface plasmon resonance (SPR) --- plastic optical fiber (POF) --- 2-furaldheide (2-FAL) --- beverages --- optical chemical sensors --- biosensor --- immunosensor --- cardiac troponin I --- single-strand DNA --- electrochemical impedance spectroscopy --- label-free --- proteins --- microfluidic chip --- self-assembled monolayers --- odor sensor --- market analysis --- technology assessment --- application field --- performance profile --- requirement profile --- biointelligence --- biological transformation --- temperature sensor --- Raman spectroscopy --- anti-Stokes/Stokes spectra --- titanium dioxide --- trypsin --- AuNPs --- acoustic wave biosensor --- colorimetric assay --- white light reflectance spectroscopy --- real-time immunosensor --- ELISA --- pesticides --- carbendazim --- fruit juices --- ECIS --- xCELLigence --- cellZscope --- hCMVEC --- endothelial cell --- impedance sensing --- light-addressable potentiometric sensor --- light-addressable electrode --- actuator-sensor system --- enzyme kinetics --- microfluidics --- HIV-1 p24 protein --- surface plasmon resonance --- surface modifications --- label-free detection --- artificial enzymes --- green synthesis --- hexacyanoferrates of transition and noble metals --- peroxidase mimetic --- amperometric (bio)sensor --- glucose oxidase --- glucose analysis --- electrocatalysis --- peroxynitrite --- flow injection analysis --- meat extracts --- myoglobin --- cobalt phthalocyanine --- electrochemical reduction --- screen-printed carbon electrode --- amperometric detection --- decay kinetics