Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Sixty years after the ""central dogma,"" great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and researchers working in laboratory but also physicians and pharmacists. This volume consists of 14 chapters, divided into 4 parts. Each chapter is written by experts investigating biological stresses, epigenetic regulation, and functions of transcription factors in human diseases. All articles presented in this volume by excellent investigators provide new insights into the studies in transcriptional control in mammalian cells and will inspire us to develop or establish novel therapeutics against human diseases.

Genetic regulation. --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Regulation --- Life Sciences --- Human Genetics --- Molecular Genetics --- Genetics and Molecular Biology --- Biochemistry

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Abiotic stresses are the major cause that limits productivity of crop plants worldwide. Plants have developed intricate machinery to respond and adapt over these adverse environmental conditions both at physiological and molecular levels. Due to increasing problems of abiotic stresses, plant biotechnologists and breeders need to employ new approaches to improve abiotic stress tolerance in crop plants. Although current research has divulged several key genes, gene regulatory networks and quantitative trait loci that mediate plant responses to various abiotic stresses, the comprehensive understanding of this complex trait is still not available. This topic is focused on molecular genetics and genomics approaches to understand the plant response/adaptation to various abiotic stresses. We welcome all types of articles (original research, method, opinion and review) that provide new insights into different aspects of plant responses and adaptation to abiotic stresses. Articles describing genome analysis to identify key candidate genes, regulatory network analysis, epigenetic regulation, discovery of novel genetic variations, QTL identification using linkage mapping and association mapping approaches, genetic engineering, molecular breeding and novel approaches for understanding and manipulation of abiotic stress response, are welcome.

Molecular genetics. --- Plants, Cultivated --- Botany --- Botany, Economic. --- Crops, Agricultural --- Genetics. --- Molecular aspects. --- microbiology. --- molecular genetics --- signal transduction --- transcriptional regulatory network --- functional genomics --- virus-induced gene silencing --- abiotic stress

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

""Central dogma"" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.

Mammals --- Cytology. --- Life Sciences --- Human Genetics --- Molecular Genetics --- Genetics and Molecular Biology --- Biochemistry

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation.

Gene therapy. --- Therapy, Gene --- Genetic engineering --- Therapeutics --- Medicine --- Medical Genetics --- Molecular Genetics --- Health Sciences

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Genetic transformation of plants has revolutionized both basic and applied plant research. Plant molecular biology and physiology benefit from this power fool, as well as biotechnology. This book is a review of some of the most significant achievements that plant transformation has brought to the fields of Agrobacterium biology, crop improvement and, flower, fruit and tree amelioration. Also, it examines their impact on molecular farming, phytoremediation and RNAi tools.

Genetic transformation. --- Life Sciences --- Human Genetics --- Molecular Genetics --- Genetics and Molecular Biology --- Biochemistry