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"Intrinsic Clocks" presents an array of current research activities on intrinsic clocks and their contributions to biology and physiology. It elucidates the current models for the intrinsic clocks, their molecular components and key mechanisms as well as the key brain regions and animal models for their behavioral analysis. It provides a timely view on how these clocks guide behavior, and how their disruption may cause depressive-like behavior and impairment in cognitive functions. Thereby, any specific method by which the mood-related functions of the intrinsic clocks might be influenced bears therapeutic potential and has clinical interest. The importance of some of these mechanisms was highlighted by the 2017 award of the Nobel Prize in Physiology or Medicine to Jeffrey C. Hall, Michael Rosbash, and Michael W. Young for their discoveries of the genetic control of the daily biological rhythm. The key to the explanation was the discovery of transcription-translation feedback loops of the so-called “clock genes.”
nocturnal --- circadian --- tanycytes --- hippocampus --- mood --- diurnal --- seasonal --- cryptochrome --- oscillation --- small-molecule
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
executive function --- cognitive control --- neural plasticity --- music training --- prefrontal cortex --- neural oscillation --- absolute pitch --- longitudinal study
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Despite increased knowledge, and more sophisticated experimental and modelling approaches, fundamental questions remain about how electricity can interact with ongoing brain function in information processing or as a medical intervention. Specifically, what biophysical and network mechanisms allow for weak electric fields to strongly influence neuronal activity and function? How can strong and weak fields induce meaningful changes in CNS function? How do abnormal endogenous electric fields contribute to pathophysiology? Topics included in the review range from the role of field effects in cortical oscillations, transcranial electrical stimulation, deep brain stimulation, modelling of field effects, and the role of field effects in neurological diseases such as epilepsy, hemifacial spasm, trigeminal neuralgia, and multiple sclerosis. The format of each (<1000 word) mini-review will begin by posing a question, problem, or challenge. The author(s) will provide a brief review of the literature and introduce essential concepts. Data regarding the outstanding question is presented, analysed, and issues of contention discussed thoroughly. The author should offer the reader an answer to the posed question if possible, and offer suggestions for future experiments to address outstanding issues.
Neurology --- Medicine --- Health & Biological Sciences --- Transcranial Magnetic Stimulation --- ephaptic --- Systems neuroscience --- brain oscillation --- transcranial direct current stimulation (tDCS) --- stimulation
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Climate change poses a serious challenge to our health and wellbeing. The increasing frequency of extreme weather events such as floods, droughts, and heatwaves, and the direct impacts of changes in temperature have direct impacts on health. At the same time, broader environmental change affects infectious disease risk, air pollution, and other forms of exposure. The different ways in which climate change will affect health are complex, interactive, and different communities are disproportionately affected. International actions such as the Paris Agreement and the Sustainable Development Goals recognise the future risks to society and acknowledge that we are already committed to a certain level of climate change. Future adaptation measures therefore need careful assessment and implementation for us to be able to minimise the potential risks from climate change and, at the same time, maximise the potential health benefits of a cleaner, greener world. This Special Issue comprises original research articles and detailed reviews on the likely impacts of climate change on health in a range of geographical settings, and the potential for adaptation measures to reduce some of these risks. Ultimately, studies like these will motivate policy level action for mitigation and help in determining the most effective methods of adaptation to reduce negative impacts in future through embedding scientific evidence into practice.
heat-waves --- heat-related mortality --- 2003 --- 2015 --- climate change --- Germany --- air temperature --- hot days --- heat waves --- city --- urban area types --- Poznań --- Poland --- ambulance 999 calls --- extreme weather --- resource planning --- London --- UK --- heat --- mortality --- adaptation --- dwellings --- indoor temperature --- cold days --- cold waves --- health systems --- climate adaptation --- health infrastructure --- rescue services --- Northern Europe --- disaster risk reduction --- Sendai Framework --- demographic change --- infectious diseases --- vector-borne diseases --- aerosolized exposures --- pollen --- well-being --- public health --- land management --- patient and public involvement (PPI) --- land-use --- El Niño Southern Oscillation --- ENSO --- health --- climatic variability --- climate-sensitive disease --- workplace --- heat stress --- productivity loss --- beta distribution --- North Atlantic Oscillation --- weather --- emergency ambulance calls --- exacerbation of essential hypertension --- urban heat island --- urban planning --- heat resilience --- climate scenarios --- waterborne disease --- natural environment --- risks --- cryptosporidiosis --- cholera --- leptospirosis --- Legionnaires’ disease --- trends over time --- n/a --- Poznań --- El Niño Southern Oscillation --- Legionnaires' disease
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Flood/drought, risk management, and policy: decision-making under uncertainty. Hydrometeorological extremes and their impact on human–environment systems. Regional and nonstationary frequency analysis of extreme events. Detection and prediction of hydrometeorological extremes with observational and model-based approaches. Vulnerability and impact assessment for adaptation to climate change.
spatial downscaling --- MODIS chlorophyll-a --- sentinel-2A MSI --- multiple polynomial regression --- genetic programming --- rainfall variability --- Indian Ocean Dipole (IOD) --- El Niño–Southern Oscillation (ENSO) --- intentional statistical simulation --- satellite-based precipitation --- hydrological modeling --- error propagation --- monsoon-climate watershed --- typhoon-induced rainfall --- prediction --- statistical model --- fuzzy C-means clustering --- China --- remote sensing --- integrated drought monitoring --- meteorological drought --- hydrological drought --- agricultural drought --- Bayesian principal component analysis (BPCA) --- statistical simulation --- extreme precipitation index --- PERSIANN-CDR --- KGE --- linear trend --- Huai River Basin --- Indian Ocean Dipole mode --- El Niño–Southern Oscillation --- singular spectrum analysis --- mutual information --- non-stationarity of seasonal precipitation
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Quels sont les rapports entre les temps, les rythmes sociaux et les pratiques liées à l'alimentation ? Dans quelle mesure celles-ci contribuent-elles à l'organisation du temps quotidien et des calendriers ? Dans quelle mesure sont-elles, en retour, réglées par les contraintes du temps ? On ne peut répondre à ces questions sans embrasser la diversité anthropologique, historique et sociale des conceptions et des usages du temps. Les études réunies dans ce volume invitent à des approches croisées : par exemple entre le temps des consommateurs et celui des producteurs, entre le temps des cultures sans horloge et le temps des sociétés hyperponctuelles, entre les civilisations qui associent temps linéaire et temps cyclique et celles qui ne croient qu'à un seul temps. Traiter du temps sous l'angle de l'alimentation aide, en spécifiant une notion spontanément concédée à la physique et à la philosophie, à la faire entrer dans le champ des sciences humaines.
Social Sciences and Humanities. Social Sciences --- Social Sciences (General). --- Nutritional anthropology --- Anthropologie de l'alimentation --- Alimentation humaine --- Comportement alimentaire --- Feeding habits --- 613.21 --- Meals: number, times, intervals etc. --- 613.21 Meals: number, times, intervals etc. --- 392.8 --- 57.034 --- 641.5 --- 641.5 Preparation of foodstuffs and meals. Cookery --- Preparation of foodstuffs and meals. Cookery --- 57.034 Cyclic variations, oscillation. Rhythmicity. --- Cyclic variations, oscillation. Rhythmicity. --- 392.8 Culinaire gewoonten. Eetgewoonten. Drinkgewoonten. Vasten. Tafeletiquette. Maaltijden. Kannibalisme --- Culinaire gewoonten. Eetgewoonten. Drinkgewoonten. Vasten. Tafeletiquette. Maaltijden. Kannibalisme --- Social change --- Human feeding --- sociocultural environment --- human population --- Nutrition --- Alimentation --- Social aspects --- Aspect social --- Sociology --- alimentation --- coutumes --- temps --- culture --- société --- Ethnologie --- Partage alimentaire --- Economie du temps --- ALIMENTATION --- NOURRITURE --- CONDITIONS SOCIALES --- VIE QUOTIDIENNE --- VIE SOCIALE --- HISTOIRE --- ANTHROPOLOGIE
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Particle physics is a science about the symmetries of our world. The Standard Model is the fundamental theory of microworld. Particle dynamics in the Standard Model obeys strict symmetry laws with explicit experimental consequences. Priority problems of particle physics based on the Standard Model are more accurate theoretical predictions, experimental measurements and data analysis, proof of existence or non-existence of supersymmetry, top quark properties, Higgs boson, exotic quark states, and physics of neutrinos. In this collection of articles, many of these problems are discussed. We recommend this book for students, graduate students, and scientists working in the field of high energy physics.
exotic states --- confined covariant quark model --- strong and radiative decays --- strong interaction --- high energy --- multiparticle production --- multiplicity --- transverse momentum --- forward-backward correlations --- long-range rapidity correlations --- translation invariance in rapidity --- quark-gluon strings --- string fusion --- high energy physics --- electron–positron annihilation --- forward–backward asymmetry --- left–right asymmetry --- top quark --- pair production --- charge asymmetry --- neutrino oscillations in matter --- rephasing invariant --- neutrino absorption --- quasi-Dirac --- neutrino oscillation --- Majorana neutrino mass --- neutrinoless double beta decay --- gravity --- relocalization --- topology --- boundary --- poles
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Superhydrophobic surfaces, with a water contact angle >150°, have attracted both academic and industrial interest due to their wide range of applications, such as water proofing, anti-fogging, antifouling, anti-icing, fluidic drag reduction and anti-corrosion. Currently the majority of superhydrophobic coatings are created using organic chemicals with low surface energy. However, the lack of mechanical strength and heat resistance prevents the use of these coatings in harsh environments. Quality superhydrophobic coatings developed using inorganic materials are therefore highly sought after. Ceramics are of particular interest due to their high mechanical strength, heat and corrosion resistance. Such superhydrophobic coatings have recently been successfully fabricated using a variety of ceramics and different approaches, and have shown the improved wear and tribocorrosion resistance properties. This Special Issue focuses on the recent developments in the fabrication of superhydrophobic coatings and their robustness against corrosion and wear resistance, but the original work on other properties of superhydrophobic coatings are also welcome. In particular, the topics of interest include, but are not limited to: Robust superhydrophobic coatings; Coatings with super-wettability in multifunctional applications; Wetting effects on corrosion and tribology; Hierarchical Coating for wetting and modelling.
n/a --- self-cleaning --- ferrofluid drop --- surface topography --- oil-water separation --- wear resistance --- super-hydrophobic coating --- parabolic morphology --- nanocomposite --- electrochemical surface engineering --- Al2O3-coated particles --- dynamic characteristics --- superhydrophobic --- stability --- suspension --- water-lubricated bearing --- chemical stability --- corrosion protection --- low friction --- friction and wear behaviour --- lubrication performance --- electrochemical deposition --- carbon steel --- TiO2 --- magnetic field --- superhydrophobic surface --- empirical formula of friction coefficient --- rough morphology --- electroless composite coating --- HVOF --- water-repellent surfaces --- corrosion resistance --- mechanical durability --- aluminum alloy --- Ni–Co --- WS2 --- thermal spray --- surfactant --- Co–Ni coating --- damped harmonic oscillation --- anodization --- etching --- MoS2 particles --- chemical etching --- truncated cone morphology --- superhydrophobic materials --- hydrophobicity --- super-hydrophobic surface --- micro-arc oxidation --- electrodeposition
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Delay, difference, functional, fractional, and partial differential equations have many applications in science and engineering. In this Special Issue, 29 experts co-authored 10 papers dealing with these subjects. A summary of the main points of these papers follows:Several oscillation conditions for a first-order linear differential equation with non-monotone delay are established in Oscillation Criteria for First Order Differential Equations with Non-Monotone Delays, whereas a sharp oscillation criterion using the notion of slowly varying functions is established in A Sharp Oscillation Criterion for a Linear Differential Equation with Variable Delay. The approximation of a linear autonomous differential equation with a small delay is considered in Approximation of a Linear Autonomous Differential Equation with Small Delay; the model of infection diseases by Marchuk is studied in Around the Model of Infection Disease: The Cauchy Matrix and Its Properties. Exact solutions to fractional-order Fokker–Planck equations are presented in New Exact Solutions and Conservation Laws to the Fractional-Order Fokker–Planck Equations, and a spectral collocation approach to solving a class of time-fractional stochastic heat equations driven by Brownian motion is constructed in A Collocation Approach for Solving Time-Fractional Stochastic Heat Equation Driven by an Additive Noise. A finite difference approximation method for a space fractional convection-diffusion model with variable coefficients is proposed in Finite Difference Approximation Method for a Space Fractional Convection–Diffusion Equation with Variable Coefficients; existence results for a nonlinear fractional difference equation with delay and impulses are established in On Nonlinear Fractional Difference Equation with Delay and Impulses. A complete Noether symmetry analysis of a generalized coupled Lane–Emden–Klein–Gordon–Fock system with central symmetry is provided in Oscillation Criteria for First Order Differential Equations with Non-Monotone Delays, and new soliton solutions of a fractional Jaulent soliton Miodek system via symmetry analysis are presented in New Soliton Solutions of Fractional Jaulent-Miodek System with Symmetry Analysis.
integro–differential systems --- Cauchy matrix --- exponential stability --- distributed control --- delay differential equation --- ordinary differential equation --- asymptotic equivalence --- approximation --- eigenvalue --- oscillation --- variable delay --- deviating argument --- non-monotone argument --- slowly varying function --- Crank–Nicolson scheme --- Shifted Grünwald–Letnikov approximation --- space fractional convection-diffusion model --- variable coefficients --- stability analysis --- Lane-Emden-Klein-Gordon-Fock system with central symmetry --- Noether symmetries --- conservation laws --- differential equations --- non-monotone delays --- fractional calculus --- stochastic heat equation --- additive noise --- chebyshev polynomials of sixth kind --- error estimate --- fractional difference equations --- delay --- impulses --- existence --- fractional Jaulent-Miodek (JM) system --- fractional logistic function method --- symmetry analysis --- lie point symmetry analysis --- approximate conservation laws --- approximate nonlinear self-adjointness --- perturbed fractional differential equations
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Real-world systems exhibit complex behavior, therefore novel mathematical approaches or modifications of classical ones have to be employed to precisely predict, monitor, and control complicated chaotic and stochastic processes. One of the most basic concepts that has to be taken into account while conducting research in all natural sciences is symmetry, and it is usually used to refer to an object that is invariant under some transformations including translation, reflection, rotation or scaling.The following Special Issue is dedicated to investigations of the concept of dynamical symmetry in the modelling and analysis of dynamic features occurring in various branches of science like physics, chemistry, biology, and engineering, with special emphasis on research based on the mathematical models of nonlinear partial and ordinary differential equations. Addressed topics cover theories developed and employed under the concept of invariance of the global/local behavior of the points of spacetime, including temporal/spatiotemporal symmetries.
time delay --- third order differential equations --- difference scheme --- stability --- ϕc-Laplacian --- boundary value problem --- critical point theory --- three solutions --- multiple solutions --- fixed point theory --- boundary value problems --- generalized attracting horseshoe --- strange attractors --- poincaré map --- electronic circuits --- non-canonical differential equations --- second-order --- neutral delay --- mixed type --- oscillation criteria --- cell transplantation --- cytokines --- ischemic stroke --- numerical simulation --- runge-kutta method --- stability analysis --- ambient assisted living --- AAL --- ambient intelligence --- assisted living --- user-interfaces --- fuzzy logic --- vibrations --- symmetrical structures --- eigenmodes --- building --- concrete --- partial difference equation --- infinitely many small solutions --- (p,q)-Laplacian
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