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Cheese is an excellent and complex food matrix that preserves in concentrated form valuable milk constituents, such as proteins, minerals, vitamins, and biofunctional lipids. The formation of cheese mass requires the removal of whey, i.e., water and soluble milk substances—proteins, minerals, lactose, and vitamins. It is well known that whey, apart from being a serious environmental threat, is a valuable substrate for the formation of new products with excellent functional and biological activities. This reprint aims to share research related to (i) cheese production, ripening, and properties, and (ii) whey and whey components’ functionality and biological value, as well as whey exploitation and processing.

ACE inhibition --- antioxidant activity --- hydrolysis --- response surface methodology --- whey protein concentrate --- Parmigiano Reggiano cheese --- somatic cells --- milk composition --- cheese yield --- cheesemaking losses --- cheese ripening --- ripening extension --- cheese microstructure --- free amino acids --- capillary electrophoresis --- proteolysis --- volatile compounds --- confocal laser scanning microscopy --- dairy product analysis --- cheese peptidomics --- cheesemaking --- data-independent acquisition --- whey --- buttermilk --- second cheese whey --- ultrafiltration --- reduced-fat cheese --- hard cheese --- long ripened cheese --- ripening rooms --- environmental ripening conditions --- quantitative descriptive analysis --- texture --- water activity --- image analysis --- cheesemaking technology --- milk whey --- hydrolyzed collagen --- bioavailability --- “bryndza” cheese --- electronic nose --- gas chromatography --- volatile organic compounds --- microbiota --- Flammulina velutipes --- protein–polysaccharide complexes --- stability --- bio-layer interferometry --- in vitro digestibility --- binding regions --- Quark-type cheese --- cow cheese milk homogenization --- cheese milk heat treatment --- sugars and organic acids --- proteolysis indices --- texture profile analysis --- whey protein denaturation --- n/a --- "bryndza" cheese --- protein-polysaccharide complexes

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Pregnancy is a viewed as a window to future health. With the birth of the developmental origins of human adult disease hypothesis, research and clinical practice has turned its attention to the influence of maternal factors such as health and lifestyle surrounding pregnancy as a means to understand and prevent the inter-generational inheritance of chronic disease susceptibility. Outcomes during pregnancy have long-lasting impacts on both women on children. Moreover, nutrition early in life can influence growth and the establishment of lifelong eating habits and behaviors. This Special Issue on “Nutrition during Pregnancy and Lactation: Implications for Maternal and Infant Health” is intended to highlight new epidemiological, mechanistic and interventional studies that investigate maternal nutrition around the pregnancy period on maternal and infant outcomes. Submissions may include original research, narrative reviews, and systematic reviews and meta-analyses.

education --- 6?-sialyllactose --- milk composition --- growth chart --- overweight and obesity --- body composition --- pregnant women --- prenatal intervention --- thermal control --- slow digesting carbohydrates --- postpartum --- vitamin B12 --- micronutrients --- passive immunization --- antibodies --- physiological body-weight loss --- obesity --- proteolysis --- energy --- infant formula --- adolescents --- pregnancy --- gestational weight gain intervention --- randomized clinical trial --- food photography --- metabolic rate --- infancy --- micronutrient deficiency --- restraint --- folate --- nutrition --- lactation --- basal maintenance expenditure --- milk oligosaccharides --- maternal nutrition --- disinhibition --- weight retention --- DNA sequencing --- neuroplasticity --- generalized linear models --- metabolic flexibility --- non-alcoholic fatty liver disease --- prematurity --- full breastfeeding --- food cravings --- transcriptome --- maternal diet quality --- Healthy Eating Index --- human milk --- gestational weight gain --- energy expenditure --- lifestyle intervention --- RDA --- immunological properties --- mindful eating --- insulin-resistant pregnancy --- nutritional intervention --- DNA methylation --- neurobiology --- total sugars --- fetal growth --- overweight --- fetal development --- energy intake --- hippocampus --- race --- maternal obesity --- early programming --- uncontrolled and emotional eating --- breast milk --- health --- hepatic lipogenesis --- eating behavior --- physical activity --- Pregnancy --- meal replacements --- premature delivery --- sialic acid --- diet quality --- cognitive development --- iron --- growth --- breastfeeding

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Biogenic amines are bioactive compounds distributed in foods of all origins. Apart from their fundamental role in many bodily functions, there has recently been great interest in their toxicological potential, much research is being carried out to understand their occurrence related to both desired and undesired fermentative phenomena, chemical spoilage, low hygienic conditions, wrong handling, and criticism about technological factors of process and storage conditions. All these causes can contribute to a higher content of biogenic amines in food, particularly of those hazardous to human health. This book aims to collect scientific studies looking for new tools to limit the over-production of biogenic amines in food, search for new food sources of biogenic amines, and to spotlight the concept of safe food and bioactive amines content.

cocoa nibs --- roasting --- bioactive amines --- polyphenols --- volatile organic compounds --- geographical areas --- biogenic amines --- L. plantarum --- amines oxidase --- Chinese rice wine --- industrial fermentation --- nigiri sushi --- polycyclic aromatic hydrocarbons --- histamine --- household smoker unit --- kimchi --- Jeotgal --- Aekjeot --- Myeolchi-jeot --- Myeolchi-aekjeot --- recommended limits --- occurrence --- reduction --- starter cultures --- biogenic amine --- maesil --- amino acids --- soaking --- fermentation --- temperature --- Cambodian fermented foods --- microbial characteristics --- food quality --- food safety --- microbiota --- Cheonggukjang --- Enterococcus faecium --- tyramine --- fermentation temperature --- fermentation duration --- tyrosine decarboxylase gene (tdc) --- proteolysis --- dry fermented sausage --- casing --- volatile compounds --- texture --- low temperature --- dried milkfish --- hygienic quality --- brine-salting --- biogenic amines (BAs) --- fermented foods --- chemometrics --- multivariate (MV) statistical analysis --- liquid chromatographic triple quadrupole mass spectrometric (LC-MS/MS) analysis --- public health --- lipid peroxidation --- antioxidants --- n/a

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Human lactation has evolved to produce a milk composition that is uniquely-designed for the human infant. Not only does human milk optimize infant growth and development, it also provides protection from infection and disease. More recently, the importance of human milk and breastfeeding in the programming of infant health has risen to the fore. Anchoring of infant feeding in the developmental origins of health and disease has led to a resurgence of research focused in this area. Milk composition is highly variable both between and within mothers. Indeed the distinct maternal human milk signature, including its own microbiome, is influenced by environmental factors, such as diet, health, body composition and geographic residence. An understanding of these changes will lead to unravelling the adaptation of milk to the environment and its impact on the infant. In terms of the promotion of breastfeeding, health economics and epidemiology is instrumental in shaping public health policy and identifying barriers to breastfeeding. Further, basic research is imperative in order to design evidence-based interventions to improve both breastfeeding duration and women’s breastfeeding experience.

Cambodia --- milk metabolomics --- galactogogues --- adequate intake --- postnatal outcomes --- cytomegalovirus --- midwifery --- milk synthesis --- chromatography --- protein --- lactoferrin --- human lactation --- ultrasound skinfolds --- breastfed infants --- knowledge --- pregnancy --- casein --- SEA --- maternal factors --- ethnicity --- post-partum distress --- bottle --- composition --- feeding --- co-sleeping --- passive immunity --- glycerophosphocholine --- anthropometrics --- antimicrobial proteins --- professional support --- mothers of preterm infants --- responsive feeding --- lactating women --- peptidomics --- triiodothyronine --- preterm --- mother–infant physical contact --- expressing --- preterm infant --- appetite regulation --- justification of supplementation --- body composition --- zinc supplementation --- antibodies --- antisecretory factor --- proteolysis --- enteral nutrition --- Ecuador --- growth factors --- maternal responsiveness --- maternal wellbeing --- nipple shield --- microbiome --- maternal distress --- sodium --- thyroid --- maternal diet --- thyroxine --- IgA --- caesarean section --- raw breast milk --- colostrum --- fatty acids --- breast milk --- immune cells --- metabolites --- PEA --- premature --- mode of delivery --- endocannabinoids --- lipids --- practice --- fat synthesis --- attitudes --- feeding cues --- infant --- Docosahexaenoic acid --- Arachidonic acid --- GDM --- milk-acquired infections --- zinc deficiency --- ICP-OES --- social support --- infants --- omega-6 fatty acids --- infant health --- HGF --- omega-3 fatty acids --- OEA --- leptin --- milk metabolites --- Canada --- mother–infant interaction --- NMR spectroscopy --- lipidomics --- infection --- breastfeeding support --- prematurity --- phosphocholine --- immunity --- Quito --- sex-specificity --- choline --- paternal role --- inflammation --- docosahexaenoic acid --- partner support --- proximal care --- thyroid antibodies --- adipokines --- calculated daily intakes --- candida --- proton nuclear magnetic resonance --- N-acylethanolamines --- milk intake --- whey --- bioelectrical impedance spectroscopy --- breastfeeding --- n-6 and n-3 polyunsaturated fatty acid --- babywearing --- milk composition --- breastmilk --- obesity --- lactation --- infant growth --- formula supplementation --- early life nutrition --- adiponectin --- milk cells --- potassium --- human milk --- long-chain polyunsaturated fatty acids --- Andean region --- Ireland --- mass spectrometry --- geographical location --- diet --- dietary recommendations --- TGF-? --- ion selective electrode --- plasma zinc --- barriers --- infant feeding --- human milk composition --- Breastfeeding

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Once viewed solely as fat storage cells, adipocytes and their adipokines have now been proven to be central for human health. Understanding that overweight and obesity may increase the risk for various diseases requires detailed characterization of adipokine function. Weight gain, weight regain, and fasting affect adipocyte health and accordingly their secretome. Different adipose tissue deposits exist and they vary in cellular composition and function. The evidence is strong of a role of adipokines in cancer, reproductive function, neurological diseases, cardiovascular diseases ,and rheumatoid arthritis. Adipokines are considered useful biomarkers for adipose tissue and metabolic health, and may be used as diagnostic tools in rheumatoid arthritis, cancer, or sepsis. This book contains 10 original articles and 9 review articles focusing on these bioactive peptides. Several articles deal with chemerin, an adipokine discovered more than 20 years ago. Data so far have resulted in promising insights related to its biological function. We are only beginning to understand the multiple roles of chemerin, the mechanisms regulating its activity, and the signaling pathways used by this chemokine. Adipokine receptor agonists and antagonists may result in the formulation of novel drugs and ultimately may lead to new therapeutic targets to be used in clinical practice.

n/a --- lipids --- cathepsins --- neurodegeneration --- tocilizumab --- SGBS adipocytes --- chemerin receptors --- cholesterol --- metabolically healthy obese --- energy metabolism --- adipose-brain axis --- EP3 receptor --- leptin --- rheumatoid arthritis --- excessive gestational weight gain --- in vitro fat regain --- secreted frizzled-related protein 5 --- PCOS --- EP4 receptor --- leukocyte --- exchange protein directly activated by cAMP isoform 2 (EPAC2) --- extracellular remodeling --- insulin --- osteoarthritis --- lipid metabolism --- fat mass --- Tango bioassay --- fatty liver --- free fatty acids --- label-free proteomic profiling --- interleukin(IL)-33 --- sick fat --- polycystic ovary syndrome --- early-life programming --- inflammation --- gestational diabetes --- glucose restriction --- adipokines --- neonatal anthropometry --- epicardial adipose tissue (EAT) --- oestrous cycle --- Cardiovascular Diseases (CVDs) --- triglycerides --- G protein-coupled receptor 1 --- testicular pathologies --- prognosis --- ovary --- ICU --- biologic activity --- preeclempsia --- adipokine --- critical illness --- early pregnancy --- myokine --- liver steatosis --- C-C chemokine receptor-like 2 --- testis --- stimulating growth factor 2 (ST2) --- pig --- fitness --- human granulosa cells --- obesity --- proteolysis --- annexins --- adipose tissue --- biomarker --- ghrelin --- brain health --- sepsis --- adiponectin --- rheumatic diseases --- chemokine-like receptor 1 --- follicular fluid --- glucose homeostasis --- resistin --- Nonalcoholic fatty liver disease --- prostaglandin E2 (PGE2) --- visceral fat --- microglia --- weight regain --- complement factors --- alpha-fetoprotein --- polycystic ovary morphology --- chemerin --- cancer --- depression --- hypertension --- hypothalamus