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Nuclear Medicine and Biology publishes original research addressing all aspects of radiopharmaceutical science: synthesis, in vitro and ex vivo studies, in vivo biodistribution by dissection or imaging, radiopharmacology, radiopharmacy, and translational clinical studies of targeted radiotracers. The importance of the target to a key disease should be the first consideration.These multidisciplinary studies should demonstrate the mechanism of localization whether the probe is based on binding to a receptor, enzyme, tumor antigen, or another well-defined target. The studies should be aimed at evaluating how the chemical properties and radiopharmaceutical preparation affect pharmacokinetics, pharmacodynamics, and therapeutic efficacy. Ideally, the study would address the sensitivity of the probe to changes in biochemistry, although studies of mechanism alone are acceptable. If the synthesis of a new radiopharmaceutical is submitted without in vitro or in vivo data, then the uniqueness of the chemistry must be emphasized. Radiopharmacy practice, addressing the issues of preparation, quality control, dispensing, and regulations applicable to qualification and administration of radiopharmaceuticals to humans, is an important aspect of the developmental process, but only if the study has a significant impact on the field. Summaries of absorbed radiation dosimetry should focus on a comparison between biodistribution/dosimetry in animals and in humans.

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Molecular Imaging. --- Nuclear Medicine. --- Radioisotopes --- Nuclear medicine --- Médecine nucléaire --- Curiethérapie --- therapeutic use. --- Periodicals. --- Therapeutic use --- Périodiques --- Nuclear medicine. --- Therapeutic use. --- radionuclide therapy --- radionuclide imaging --- perfusion imaging --- scintigraphy --- positron-emission tomography --- molecular imaging --- Medicine, Atomic --- Medicine, Nuclear --- Radiology, Nuclear --- Atomic Medicine --- Nuclear Radiology --- Nuclear Pharmacy --- Radiobiology --- Imaging, Molecular --- Radioactive isotopes --- Radioactive nuclides --- Radionuclides --- Isotopes --- Nuclear engineering --- Radioactive substances --- Radiochemistry --- Radioisotope therapy --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Physiological effect --- Physical methods for diagnosis

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Physical methods for diagnosis --- Radiotherapy. Isotope therapy --- nuclear physics --- Nuclear physics --- Nuclear Medicine --- Diagnostic Imaging --- Diagnostic Techniques, Radioisotope --- Radioisotopes --- Nuclear medicine --- Diagnostic imaging --- Médecine nucléaire --- Imagerie pour le diagnostic --- Curiethérapie --- therapeutic use --- Periodicals --- Therapeutic use --- Périodiques --- Nuclear Medicine. --- Diagnostic Imaging. --- Diagnostic Techniques, Radioisotope. --- Diagnostic imaging. --- Nuclear medicine. --- therapeutic use. --- Medicine, Atomic --- Medicine, Nuclear --- Radiology, Nuclear --- Atomic Medicine --- Nuclear Radiology --- Radiobiology --- Health Sciences --- General and Others --- Cytology, Cell Biology --- Genetics --- Metabolism --- Micro and Molecular Biology --- Life Sciences --- Nuclear Pharmacy --- Health Sciences. --- Micro and Molecular Biology. --- Life Sciences. --- Molecular Imaging. --- Atomic medicine --- Radioisotopes in medicine --- Clinical imaging --- Imaging, Diagnostic --- Medical diagnostic imaging --- Medical imaging --- Noninvasive medical imaging --- Diagnostic Technic, Radioisotope --- Diagnostic Technics, Radioisotope --- Diagnostic Technique, Radioisotope --- Radioisotope Diagnostic Technic --- Radioisotope Diagnostic Technics --- Radioisotope Diagnostic Technique --- Radioisotope Diagnostic Techniques --- Technic, Radioisotope Diagnostic --- Technics, Radioisotope Diagnostic --- Technique, Radioisotope Diagnostic --- Techniques, Radioisotope Diagnostic --- Imaging, Medical --- Medical Imaging --- Medical radiology --- Radioactive tracers --- Radioactivity --- Diagnosis, Noninvasive --- Imaging systems in medicine --- Radiologic and Imaging Nursing --- Image Processing, Computer-Assisted --- Physiological effect --- MDNUCLEA --- Kernfysica --- Radiotherapie. Isotopentherapie --- Fysische diagnosetechnieken --- kernfysica --- Daughter Nuclides --- Daugter Isotopes --- Radiogenic Isotopes --- Radioactive Isotopes --- Radionuclides --- Isotopes, Daugter --- Isotopes, Radioactive --- Isotopes, Radiogenic --- Nuclides, Daughter --- Elements --- Isotopes --- farmacologie --- Radiology, MRI, Ultrasonography & Medical Physics --- Nuclear Medicine - periodicals --- Diagnostic Imaging - periodicals --- Diagnostic Techniques, Radioisotope - periodicals --- Radioisotopes - therapeutic use - periodicals