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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
mass spectometry --- MALDI-TOF --- susceptibility testing --- carbapenamase --- resistance detection --- MRSA - Methicillin-resistant Staphylococcus aureus
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Methicillin resistant Staphylococcus aureus (MRSA) --- Methicillin susceptible S. aureus (MSSA) --- MRSA protracted outbreaks --- Whole-genome sequencing --- evolution --- Molecular Epidemiology --- antimicrobial resistance --- Point of Care Testing --- staphylococcal mobile genetic elements --- staphylococcal cassette chromosome mec (SCCmec)
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
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Although 30% of the healthy human population is colonized with various Staphylococcus species, some staphylococcal strains, referred to as opportunistic pathogens, can cause minor to life-threatening diseases. The pathogenicity of these bacteria depends on their virulence factors and the robustness of the regulatory networks expressing these virulence factors. Virulence factors of pathogenic Staphylococcus spp. consist of numerous toxins, enterotoxins (some of which act as superantigens), enzymes, and proteins (cytoplasmic, extracellular, and surface) that are regulated by two-component (TC) and quorum-sensing (QS) regulatory networks. To enter this niche, some other Staphylococcus species, such as Staphylococcus simulans, produce a potent endopeptidase called lysostaphin, which can inhibit the growth of pathogenic S. aureus. Some other Staphylococcus species produce autolysins and cationic peptides to win the intra- and inter-species competition. The outcome of this microbial invasion depends not only on pathogenic factors but also on the host’s internal and external defense mechanisms, including a healthy skin microbiome. A healthy skin microbiome population can prevent colonization by other major pathogens. As normal host microflora, these commensals establish a complex relationship with the host as well as the surrounding microbial communities. This Special Issue of Microorganisms is focused on studies and recent advancements in our understanding of staphylococcal virulence mechanisms that enable Staphylococcus spp. either to successfully establish themselves as a colonizer or to overcome the host’s defense system to cause infection along with our effort to make an anti-staphylococcal vaccine.
biofilm --- MRSA --- silver ion --- silver sulfadiazine --- wound infections --- Staphylococcus aureus --- methicillin resistance --- human infection --- CC130 --- biomaterials --- medical devices --- HL-60 cells --- PMNs --- endotracheal tube --- titanium --- implantable devices --- nosocomial diseases --- Staphylococcus lugdunensis --- sortase A --- surface proteins --- LPXTG --- small colony variants --- influenza virus --- super-infection --- pro-inflammatory response --- rural Ghana --- molecular epidemiology --- chronic wounds --- invasive disease --- surgery-associated infection --- sepsis --- SA4Ag vaccine --- conjugated polysaccharide --- ClfA --- MntC --- protection --- animal models --- phase variation --- Staphylococcus epidermidis --- microbiota --- multidrug resistance --- genome sequencing --- phylogenetic analyses --- arthroplasty surgery --- methicillin-resistant Staphylococcus aureus (MRSA) --- community-associated MRSA (CA-MRSA) --- CA-MRSA strain USA300 --- murine skin infection model --- dermatopathology --- dermonecrosis --- neutrophil --- host antibacterial response --- cytokine --- chemokine --- physiology --- metabolism --- carbon catabolite repression --- CcpA --- HPr --- colonization --- mouse --- JSNZ --- aurintricarboxylic acid --- ATA --- adhesion inhibitor --- mupirocin --- nose --- superantigen --- mastitis --- food intoxication --- regulation --- sec variants --- CM lipids --- daptomycin resistance --- resensitization --- n/a
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Air pollution, due to natural and anthropogenic sources, incurs enormous environmental costs. The issue of healthy living spaces and good air quality is a global concern, because each individual inhales 15,000 L of air every 24 h. Thus, contemporary monitoring and reducing exposure to air pollutants presents a particular challenge. One of the crucial indicators of indoor and outdoor air quality is bioaerosols. They play an instrumental role as risk factors when it comes to adverse health outcome. These indicators, also known as primary biological airborne particles (PBAPs), have been linked to various health effects such as infectious diseases, toxic effects, allergies, and even cancer. PBAPs include all particles with a biological source in suspension in the air (bacteria, fungi, viruses, and pollen), as well as biomolecules (toxins, and debris from membranes). To foster our current scientific knowledge on bioaerosols, research related to the characteristics of biological aerosols in indoor and outdoor environments, the methods used to improve air quality, as well as the health effects of and exposure assessments to bioaerosols, have been collected in this book.
radiant catalytic ionization --- Enterococcus spp. --- Clostridioides difficile --- Staphylococcus aureus --- MRSA --- indoor air --- microbiological indoor air quality (MIAQ) --- bacterial aerosol (BA) --- size distribution --- gymnastic hall --- multi-antibiotic resistance (MAR) --- indoor microclimate --- decentralized façade ventilation --- air quality --- indoor air quality --- microbiological contamination --- heterotrophic bacteria --- antimicrobial resistance --- mannitol-positive staphylococci --- fungi --- biological air pollutants --- fungal aerosol --- air cleaner --- life cycle assessment --- n/a --- decentralized façade ventilation
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Bacterial resistance to known and currently used antibiotics represents a growing issue worldwide. It poses a major problem in the treatment of infectious diseases in general and hospital-acquired infections in particular. This is in part due to the overuse and misuse of antibiotics in past decades, which led to the selection of highly resistant bacteria and even so-called superbugs – multidrug-resistant (MDR) bacteria. Nosocomial infections, particularly, are often caused by MDR bacterial pathogens and the treatment of such infections is very complicated and extensive, often leading to various side effects, including adverse effects on the natural human microbiome. At the same time, the development of novel antibiotics is lagging with very few new ones in the pipeline. Finding viable alternatives to treat such infections may help to overcome these therapeutic issues. This publication brings novel developments in the field of bacterial resistance, mainly in the hospital settings, adequate antibiotic therapy, and identification of compounds useful to battle this growing issue.
VRE --- GIT --- hemato-oncological patients --- clonality --- antibiotic stewardship --- resistance --- consumption of antibiotics --- clonal spread --- Enterococcus faecium --- Enterococcus faecalis --- linezolid resistance --- 23S rRNA --- optrA --- carbapenem-resistant Klebsiella pneumoniae --- carbapenem-resistant Acinetobacter baumannii --- N-acetylcysteine --- septic shock --- critically ill patients --- newborn --- infection --- bacteria --- antibiotic therapy --- hops --- C. difficile --- rat model --- Staphylococcus aureus --- MRSA --- spa typing --- MLST --- SCCmec typing --- clonal analysis --- epidemiology --- cancer patients --- duration of treatment --- colistin --- propensity score analysis --- multidrug-resistant Acinetobacter baumannii --- urinary tract infections --- UTIs --- MDR --- Escherichia coli --- Klebsiella --- uropathogens --- AMR --- antibiotic resistance --- ESBL-producing Klebsiella pneumoniae --- urinary tract infection --- clinical impact --- economic impact --- ventilator-associated pneumonia --- Klebsiella spp. --- Escherichia spp. --- pulsed-field gel electrophoresis (PFGE) --- endogenous infection --- methicillin-resistant --- porcine model --- methicillin-resistant Staphylococcus aureus (MRSA) --- long term care facilities (LTCF) --- multidrug resistance (MDR) --- enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) --- ESBL --- PCR --- primer --- antimicrobial resistance --- infection prevention and control --- antimicrobial stewardship --- hospital --- cluster analysis --- principal component analysis
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Het Handboek wondzorg is een geactualiseerde bundeling van het Basisboek wondzorg en Specifieke wondzorg deel 1 en 2, oorspronkelijk uitgebracht in 1997. Kleurenillustraties ondersteunen de veelal herschreven theorie. Bovendien zijn de belangrijkste wondzorgontwikkelingen van de afgelopen zes jaar in de tekst verwerkt. Een praktische toevoeging is de productbijlage die samen met wondproductfabrikanten is samengesteld. Deze volledig herziene uitgave is een praktisch handboek voor zorgverleners. Het is bijzonder geschikt voor gebruik in de extra- en intramurale zorg. Daarnaast kan het boek uitstekend dienstdoen als studieboek in het reguliere verpleegkundeonderwijs en bij wondzorggerelateerde nascholingscursussen. Handboek wondzorg levert een bijdrage aan het comfort van de patiënt met een wond en aan de optimalisering van de wondzorg. Dit boek behandelt de theoretische achtergronden van de huid en gaat in op specifieke wondtypes zoals decubitus en brandwonden. Tevens beschrijft deze uitgave wondpijn en de relatie tussen wondzorg en voeding. (Bron: covertekst)
071316.jpg --- Decubitus --- Wondbehandeling --- Brandwonden --- Allergieën --- multiresistente micro-organismen --- oncologisch wonden --- oogtrauma --- Wounds and Injuries. --- 616-001 --- Verwondingen --- MRSA (Methicillineresistente Staphylococcus Aureus) --- débridement --- larventherapie --- postoperatieve wonden --- psychosociale aspecten --- skin tears --- stoma --- vacuüm assisted wound closure --- Brandwonden (brandwond) --- Decubitus (doorligwonde, drukwonden) --- MRSA --- Oncologische wonden --- Postoperatieve wondinfectie --- Stoma --- Tracheostomie --- Tracheotomie --- Ulcus cruris --- Verbanden (bandage, buisverband) --- contactallergie --- methicillineresistente staphylococcus aureus --- oncologische wonden --- oogverzorging --- wondreiniging --- wondverzorging (gez) --- huidallergie --- maden (larventherapie) --- stafylokokkeninfectie (MRSA) --- vacuum assisted closure --- First Aid --- Traumata. Injuries. Wounds --- Brûlures --- Décubitus --- Plaies et blessures --- 616-001 Traumata. Injuries. Wounds --- 616-083 --- wondverzorging --- 613.2 --- verpleegkunde --- Chirurgie --- Pijn --- Traumatologie --- 613.21 --- allergie --- brandwonden --- decubitus --- diabetische voet --- geneeskunde --- gezondheidszorg --- handhygiëne --- oncologie --- ontsmettingsmethoden --- oog --- pijn --- tracheotomie --- traumatologie --- ulcus cruris --- verbanden --- wondgenezing --- wondinfectie --- Diabetische voet --- Handhygiëne --- Wondzorg --- 616.083 ) Wondverzorging --- postoperatieve wondinfectie --- wondzorg --- 613.6 --- brandwond --- decubitus (doorligwond, drukletsels) --- dieet (diëtetiek) --- kwaadaardige gezwellen (kanker, sarcoom) --- postoperatieve zorgen --- stoma (anus praeternaturalis, kunstmatige anus) --- ulcus cruris (open been) --- wondhechting --- Injuries and Wounds --- Injuries, Wounds --- Research-Related Injuries --- Wounds --- Wounds and Injury --- Wounds, Injury --- Injuries --- Trauma --- Injuries, Research-Related --- Injury --- Injury and Wounds --- Injury, Research-Related --- Research Related Injuries --- Research-Related Injury --- Traumas --- Wound --- 616-083 Hypurgy. Care of patient. Hygiene of the sick. Nursing --- Hypurgy. Care of patient. Hygiene of the sick. Nursing --- verpleegkunde - inleidingen --- Douleur --- Basisverpleegkunde - Verpleegkundige interventies --- (zie ook: endocrinologie, gynecologie, hematologie) --- (zie ook: analgesie) --- (zie ook: orthopedie) --- (zie ook: postoperatieve wondinfectie) --- Traumatology --- Wounds and Injuries
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InhoudsopgaveDeel 1: Preventie1 Inleidende begrippen infectiepreventie2 Standaard voorzorgsmaatregelen3 Persoonlijke hygiëne van de zorgverlener4 Handhygiëne5 Beschermingskledij6 Isolatierichtlijnen7 Reinigen en desinfectie8 Linnen9 Afval van gezondheidsinstellingen10 Accidenteel contact met bloed en lichaamsvochten11 StralingshygiëneDeel 2: Infecties1 Multiresistente bacteriën2 Gastro-interitis in gezondheidsinstellingen3 Scabiës4 Influenza
Hospital infections --- Hospital-acquired infections --- Infections nosocomiales --- Nosocomial infections --- Ziekenhuisinfecties --- preventie --- Cross Infection --- Infection Control --- infectiepreventie --- 613.49 --- aids --- bacteriologie --- gastro-enteritis --- gezondheidszorg --- griep --- handhygiëne --- hepatitis --- hygiëne --- individuele hygiëne --- infectiebestrijding --- scabiës --- straling --- verpleegkunde --- ziekenhuishygiëne --- 614.44 --- Bacteriële infecties --- Besmettelijke ziekten (babesiosis,infectie, infectieziekten) --- Besmettelijke ziekten (bacteriëel) (bacteriële infectieziekten) --- Enteritis --- Griep (influenza) --- Handhygiëne --- Infectiepreventie (desinfectie) --- Infectiepreventie --- Isolering (infectiepreventie) --- MRSA --- Prikongevallen --- Scabies (acariasis) --- Scabies --- Ziekenhuishygiëne --- Ziekenhuisinfecties (nosocomiale infecties) --- 613.4 --- besmettelijke ziekten (gez) --- preventie (gez) --- Besmettelijke ziekten --- Preventie --- Radioactieve-stralen protectie --- prevention & control. --- organization & administration. --- Overige onderwerpen --- preventie. --- Preventie. --- Hygiene. Public health. Protection --- stafylokokkeninfectie --- immunologie --- Prevention --- prevention & control --- organization & administration
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Academic collection --- 616.053.9 --- 605.93 --- ADL (Activteiten Dagelijks Leven, Katz-schaal, zelfredzaamheid) --- Pagetziekte --- RVT (rustoord, rust- en verzorgingstehuis) --- Wegenerziekte --- andrologie --- audiometrie --- bejaardenpsychologie --- bejaardentehuis --- borstkanker --- cholelithiasis (galstenen) --- dementie (dementia, dementia senilis) --- ergonomie --- eten (maaltijdgebeuren) --- gastrostomie --- geheugen --- geneesmiddelen --- geriatrie --- gerontologie (verouderingsproces) --- intimiteit --- kankerregistratie (kankerpreventie) --- maagintubatie --- maagkatheterisatie --- osteoporose --- partnerrelatie --- pensioen --- percutane endoscopische gastrotomie --- pneumologie (ademhalingsziekten, longziekten, luchtwegenziekten) --- psychofarmaca --- psychogeriatrie (ouderenpsychiatrie) --- reanimatie --- rugpijn (ischias, lagerugpijn, lumbago) --- seksualiteit --- seksuele afwijking --- stafylokokkeninfectie (MRSA) --- thuiszorg --- vallen --- vasculitis --- voedingshygiëne (voedingsgewoonten) --- (zie ook: verpleeghuis) --- (zie ook: geriatrie, gerontologie) --- (zie ook: geriatrie) --- (zie ook: gynecologie) --- (zie ook: gerontologie) --- (zie ook: kwaadaardige gezwellen) --- Conferences - Meetings
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The search for bioactive secondary metabolites from marine organisms has been an active area of research since the 1950s. The distinct biodiversity of the marine environment has afforded a vast array of unique secondary metabolites, many of which possess potent biological activities. This Special Issue of Marine Drugs will highlight recent bioactive marine natural product studies conducted by southern hemisphere scientists on an array of marine organisms.
Sinularia --- Alcyoniidae --- anticancer activity --- lobane --- cembrane --- diterpene --- conotoxins --- ShK toxin --- ion channels --- docking --- molecular dynamics --- potential of mean force --- free energy perturbation --- bioactivity --- biosynthesis --- brominated secondary metabolites --- choline ester --- indole --- sea cucumber --- viscera --- saponins --- mass spectrometry --- MALDI --- ESI --- HPCPC --- triterpene glycosides --- structure elucidation --- bioactive compounds --- marine invertebrate --- Echinodermata --- holothurian --- Cnemidocarpa stolonifera --- taurine amide --- PC3 cell line --- immunofluorescence assay --- thiaplidiaquinone --- Aplidium --- ascidian --- thiazinoquinone --- apoptosis --- Jurkat --- cytotoxicity --- malaria --- farnesyltransferase --- synthesis --- thiaplakortone --- regioisomer --- tricyclic --- natural product scaffold --- X-ray --- crystal --- Plasmodium falciparum --- antiplasmodial --- cephalostatin --- mandelalide --- methicillin resistant Staphylococcus aureus --- MRSA PK --- bisindole alkaloids --- salternamide A (SA) --- HIF-1α --- PI3K/Akt/mTOR --- p42/p44 MAPK --- STAT3 --- cell death
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