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Liver regeneration and carcinogenesis : molecular and cellular mechanisms
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ISBN: 128103309X 9786611033095 0080535542 0123853559 9780123853554 9780080535548 Year: 1995 Publisher: San Diego : Academic Press,

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Abstract

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of research disciplines. This book brings together current fin


Book
Liver regeneration : basic mechanisms, relevant models and clinical applications
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ISBN: 0128004312 0124201288 9780128004319 9780124201286 Year: 2015 Publisher: London, UK ; San Diego, CA ; Waltham, MA : Elsevier,

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Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease. By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management. Hundre


Book
Developments in tissue engineered and regenerative medicine products : a practical approach
Authors: ---
ISBN: 1908818115 190756876X 9781908818119 9781907568763 Year: 2012 Volume: no. 48 Publisher: Cambridge : Woodhead Pub.,

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Developments in tissue engineered and regenerative medicine products summarizes recent developments in tissue engineering and regenerative medicine with an emphasis on commercialization and product development. Features of current cell therapy and tissue engineered products which have facilitated successful commercialization are emphasized and roadblocks to successful product development are also highlighted. Preclinical and clinical testing of tissue engineered and regenerative medicine products, regulatory, quality control, manufacturing issues, as well as generating and securing intellectua


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Bioengineering Liver Transplantation
Authors: --- ---
ISBN: 3039217453 3039217445 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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The aim of this Special Issue is to review, understand, and evaluate new and exciting opportunities from the field on regenerative medicine, biomaterials, and stem cell research for the bioengineering of human liver grafts that can be applied for transplantation and personalized treatment of end-stage liver disease.The development of culture conditions for long-term expansion of LGR5+ intestinal stem cells as crypt-villus structures demonstrated the feasibility of deriving complex, organ-like structures in vitro from primary adult tissues, including the liver. Moreover, human pluripotent stem cells (hPSCs) can be applied to generate functionally maturated liver and bile duct epithelial cells.In this Special Issue, we welcome reviews and original papers focussing on hepatic cell sources, including adult hepatic stem cells, organoids, fetal and induced pluripotent stem cells, and primary cells (i.e., hepatocytes, cholangiocytes, and endothelial cells) and how these cells can be applied in tissue engineering strategies to generate implantable and personalized liver grafts. Potential topics include, but are not limited to, the following: liver tissue engineering, liver regeneration, graft repair, liver stem cells and organoids, bio-scaffolds, and 3D printing.We invite you to contribute original research papers, as well as comprehensive reviews, aligned with these themes, to advance and improve the actual state-of-the-art in liver bioengineering and providing new opportunities for the imminent medical problem of organ and tissue shortage for transplantation.


Book
Biological and Pharmacological Activity of Plant Natural Compounds II
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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The Special issue "Biological and Pharmacological Activity of Plant Natural Compounds II" is continuing the intriguing research on the use of natural plant products. The second edition follows the aim of the first one.

Keywords

Bergenia species --- botanical description --- traditional uses --- phytochemistry --- pharmacology --- anti-urolithiatic activity --- bergenin --- Flaxseed oil --- linusorb B3 --- anti-cancer --- apoptosis --- actin polymerization --- Src --- glioblastoma --- chlorogenic acid --- coffee --- cyclooxygenase --- espresso --- instant coffee --- platelet aggregation --- Rubia tinctorum L. --- antioxidants --- polyphenols --- ethylene glycol --- urolithiasis --- histophatology --- Saccharomyces cerevisiae --- β-glucan --- antimicrobial and anticancer activities --- detoxification ability --- immunomodulatory effect --- Aquilaria sinensis --- pheophorbide A --- MMP-2 --- MMP-9 --- HT-1080 --- advanced glycation end product (AGE) --- oxidative stress --- epithelial to mesenchymal transition --- AGE-inhibitor --- swertiamarin --- diabetic nephropathy --- astragaloside IV --- Astragalus membranaceus --- huang qi --- Astragali Radix --- liver --- liver regeneration --- 70% partial hepatectomy --- proliferation --- rat --- memory --- object recognition --- Ginkgo biloba --- dorsal hippocampus formation --- brain-derived neurotrophic factor --- Diclofenac --- γ-lactone --- nano-emulsion --- methylcellulose --- Ostrich oil --- Struthio camelus --- Caenorhabditis elegans --- leaf extract --- neuroprotection --- antioxidant activity --- DAF-16 --- Clerodendrum infortunatum --- terpenoids --- phenylpropanoids --- antidiabetic --- breast cancer --- Combretum indicum L. --- antidiabetic activity --- histopathology --- UPLC-QTOF/ESI-MS --- network pharmacology --- Biebersteinia heterostemon --- galegine --- hypotensive --- toxicity --- Sage --- Salvia officinalis --- cytotoxicity --- hepatoprotection --- MDA --- TAOxC --- MCF-7 --- HeLA cells --- HepG-2 cells --- Peganum harmala --- anti-inflammatory activity --- antioxidant --- LC-ESI-MS/MS --- traditional medicine --- rheumatoid arthritis --- rosmanol --- carnosol --- Callicarpa longissima --- TLR4/NF-κB/MAPK --- synergistic effect --- diabetes mellitus --- anti-diabetic drugs --- monoterpenes

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