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Methamphetamine abuse --- Methamphetamine

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Methamphetamine abuse --- Amphetamine abuse --- Treatment. --- Prevention.

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Jeffrey W. Alexander examines how Western alcohol and innovative pharmaceuticals became so popular, available, and fashionable in Japan. He considers the people who brewed, distilled, synthesized, and marketed these products and explores what their advertising campaigns say about Japan's shifting culture.

Methamphetamine abuse. --- Substance abuse. --- Whiskey industry.

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Methamphetamine (ice, speed, crystal, shard) has been called epidemic in the United States. Yet few communities were ready for increased use of methamphetamine by suburban women. Women on Ice is the first book to study exclusively the lives of women who use the drug and its effects on their families. In-depth interviews with women in the suburban counties of one of the largest metropolitan areas in the U.S. chronicle the details of their initiation into methamphetamine, the turning points into problematic drug use, and for a few, their escape from lives veering out of control. Their life course and drug careers are analyzed in relation to the intersecting influences of social roles, relationships, social/political structures, and political trends. Examining the effects of punitive drug policy, inadequate social services, and looming public health risks, including HIV/AIDS and hepatitis C, the book gives voice to women silenced by shame. Boeri introduces new and developing concepts in the field of addiction studies and proposes policy changes to more broadly implement initiatives that address the problems these women face. She asserts that if we are concerned that the war on drugs is a war on drug users, this book will alert us that it is also a war on suburban families.

Drug addiction --- Women drug addicts. --- Methamphetamine abuse. --- Women --- Drug addicts --- Amphetamine abuse --- Treatment. --- Drug use.

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The purpose of this collection is to provide a forum to integrate pre-clinical and clinical investigations regarding the long-term consequences of adolescent exposure to drugs of abuse. Adolescence is characterized by numerous behavioral and biological changes, including substantial neurodevelopment. Behaviorally, adolescents are more likely to engage in risky activities and make impulsive decisions. As such, the majority of substance use begins in adolescence, and an earlier age of onset of use (<15 yr) is strongly associated with the risk for developing a substance use disorder later in life. Furthermore, adolescent drug use may negatively impact ongoing neurological development, which could lead to long-term cognitive and emotional deficits. A large number of clinical studies have investigated both the acute and long-term effects of adolescent drug use on functional outcomes. However, the clinical literature contains many conflicting findings, and is often hampered by the inability to know if functional differences existed prior to drug use. Moreover, in human populations it is often very difficult to control for the numerous types of drugs, doses, and combinations used, not to mention the many other environmental factors that may influence adult behavior. Therefore, an increase in the number of carefully controlled studies using relevant animal models has the potential to clarify which adolescent experiences, particularly what drugs used when, have long-term negative consequences. Despite the advantages of animal model systems in clarifying these issues, the majority of pre-clinical addiction research over the past 50+ years has been conducted in adult animals. Moreover, few addiction-related studies have investigated the long-term neurocognitive consequences of drug exposure at any age. In the past 10 years of so, however, the field of adolescent drug abuse research has burgeoned. To date, the majority of this research has focused on adolescent alcohol exposure using a variety of animal models. The results have given the field important insight into why adolescents are more likely to drink alcohol to excess relative to adults, and the danger of adolescent alcohol use (e.g., in leading to a persistence of excessive drinking in adulthood). More recently, research regarding the effects of adolescent exposure to other drugs of abuse, including nicotine, cocaine, and cannabinoids has expanded. Therefore, we are at unique point in time, when emerging results from carefully controlled pre-clinical studies can inform the sometimes confusing clinical literature. In addition, we expect an influx of prospective clinical studies in response to a cross-institute initiative at NIH, known as the ABCD grant. Several institutes are enrolling children prior to adolescence (and the initiation of drug use), in order to control for pre-existing neurobiological and neurobehavioral differences and to monitor the age of initiation and amount of drug used more carefully than is possible using retrospective designs.

alcohol --- stress --- nicotine --- cocaine --- ketamine --- methamphetamine --- cannabinoid --- prefrontal cortex --- juvenile --- sex differences