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tobacco --- public health --- health policy --- smoking cessation --- smoking prevention --- Smoking cessation --- Smoking --- Tobacco use --- Tobacco Use Cessation. --- Tobacco Use --- Tobacco Use Disorder. --- Health aspects --- Prevention --- Treatment. --- prevention & control. --- Tobacco habit --- Cigarette habit --- Cigarette smoking cessation --- Giving up smoking --- How to stop smoking --- Quitting smoking --- Smoking cessation programs --- Stopping smoking --- Cigarette smokers --- Habit breaking --- Nicotine addiction --- Tobacco-Use Disorder --- Nicotine Dependence --- Nicotine Use Disorder --- Tobacco Dependence --- Dependence, Nicotine --- Dependence, Tobacco --- Disorder, Nicotine Use --- Disorder, Tobacco Use --- Disorder, Tobacco-Use --- Nicotine Use Disorders --- Tobacco Dependences --- Tobacco Use Disorders --- Use Disorder, Nicotine --- Tobacco --- Tobacco Cessation --- Smokeless Tobacco Cessation --- Cessation, Smokeless Tobacco --- Cessation, Tobacco --- Cessation, Tobacco Use --- Cessations, Tobacco Use --- Smoking Reduction --- Tobacco Use Disorder --- Tobacco Use Cessation Products --- Habit --- Substance abuse --- Cigarette smoking --- Tobacco smoking --- Rehabilitation --- Treatment --- Tobacco Use Cessation Devices --- Public Health - General --- Nicotine Addiction --- Addiction, Nicotine --- Nicotine Addictions

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Smoking cessation - United States. --- Tobacco use --- Smoking --- Smoking cessation --- Public Policy --- Tobacco Use Disorder --- Tobacco Industry --- Social Control Policies --- Substance-Related Disorders --- Industry --- Policy --- Mental Disorders --- Social Control, Formal --- Diseases --- Technology, Industry, and Agriculture --- Technology, Industry, Agriculture --- Psychiatry and Psychology --- Social Sciences --- Health Care Economics and Organizations --- Sociology --- Anthropology, Education, Sociology and Social Phenomena --- Health Care --- Substance Abuse --- Social Welfare & Social Work --- Government policy --- Prevention --- Prevention. --- Tobacco habit --- Cigarette habit --- Cigarette smoking --- Tobacco smoking --- Habit --- Substance abuse --- Nicotine addiction

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Tobacco Use. --- Tobacco Use Disorder --- Nicotine --- Nicotine addiction --- Tobacco --- Tobacco use --- Tabagisme --- Tabac --- therapy. --- Physiological effect --- Periodicals --- Treatment --- Health aspects --- Periodicals. --- Aspect physiologique --- Périodiques --- Traitement --- Effets physiologiques --- Aspect sanitaire --- Tobacco use. --- Treatment. --- Physiological effect. --- Health aspects. --- Tobacco habit --- Cigarette smoke --- Cigarettes --- Smoking --- Mahorka --- Makhorka --- Nicotiana tabacum --- Cigarette habit --- Nicotine dependence --- Tobacco addiction --- Tobacco dependence --- Tobacco Chewing --- Tobacco Consumption --- Chewing, Tobacco --- Consumption, Tobacco --- Tobacco Uses --- Habit --- Substance abuse --- Nicotiana --- Drug addiction --- Alkaloids --- Pyridine --- Tobacco products --- tobacco use --- smoking cessation --- nicotine addiction --- tobacco-related cancer --- Human medicine

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The journal encompasses all aspects of tobacco induced diseases, including their underlying mechanisms, as well as the prevention of tobacco addiction

Tobacco use --- Tobacco --- Smoking --- Tabagisme --- Tabac --- Health aspects --- Periodicals. --- Physiological effect --- Toxicology --- Periodicals --- Prevention --- Aspect sanitaire --- Périodiques --- Effets physiologiques --- Toxicologie --- Prévention --- Nicotine addiction. --- Smoking. --- Internal medicine --- Tobacco Use Disorder. --- Internal medicine. --- adverse effects. --- Physiological effect. --- Health aspects. --- Substance-Related Disorders. --- Tobacco habit --- Cigarette smoke --- Cigarettes --- Medicine, Internal --- Tobacco-Use Disorder --- Nicotine Dependence --- Nicotine Use Disorder --- Tobacco Dependence --- Dependence, Nicotine --- Dependence, Tobacco --- Disorder, Nicotine Use --- Disorder, Tobacco Use --- Disorder, Tobacco-Use --- Nicotine Use Disorders --- Tobacco Dependences --- Tobacco Use Disorders --- Use Disorder, Nicotine --- Substance Addiction --- Drug Abuse --- Drug Addiction --- Drug Dependence --- Drug Habituation --- Drug Use Disorders --- Organic Mental Disorders, Substance-Induced --- Substance Abuse --- Substance Dependence --- Substance Use Disorders --- Abuse, Drug --- Abuse, Substance --- Abuses, Substance --- Addiction, Drug --- Addiction, Substance --- Dependence, Drug --- Dependence, Substance --- Disorder, Drug Use --- Disorder, Substance Use --- Drug Use Disorder --- Habituation, Drug --- Organic Mental Disorders, Substance Induced --- Substance Abuses --- Substance Use Disorder --- Mahorka --- Makhorka --- Nicotiana tabacum --- smoking --- tobacco cessation --- tobacco use --- cigarette smoking --- tobacco smoke --- disease prevention --- Medicine --- Prescription Drug Abuse --- Abuse, Prescription Drug --- Drug Abuse, Prescription --- Drug and Narcotic Control --- Disruptive, Impulse Control, and Conduct Disorders --- Psychoses, Alcoholic --- Social Problems --- Street Drugs --- Designer Drugs --- Behavior, Addictive --- Codependency (Psychology) --- Alcohol-Related Disorders --- Prescription Drug Misuse --- Habit --- Substance abuse --- Nicotine addiction --- Nicotiana --- Tobacco Related Diseases. --- Illicit Drugs --- Codependency, Psychological --- Nicotine Addiction --- Addiction, Nicotine --- Nicotine Addictions --- Chemical Dependence --- Substance Use --- Chemical Dependences --- Dependence, Chemical --- Dependences, Chemical --- Substance Uses --- Use, Substance --- Oncology. Neoplasms --- Pathology of the respiratory system --- Substance Related Disorder --- Disorder, Substance Related --- Disorders, Substance Related --- Related Disorder, Substance --- Related Disorders, Substance

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The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacology (Limbird 2004; Halliwell 2007), and led the pioneering researcher John Langley to conclude that there must exist some “- ceptive substance” to explain the diverse actions of various substances, including nicotine, when applied to muscle tissue (Langley 1905). Research on tobacco and nicotine progressed throughout the twentieth century, but much of this was from a general pharmacological and toxicological rather than a psychopharmacological perspective (Larson et al. 1961). There was some attention to the effects related to addiction, such as euphoria (Johnston 1941), tolerance (Lewin 1931), and withdrawal (Finnegan et al. 1945), but outside of research supported by the tobacco industry, addiction and psychopharmacology were not major foci for research (Slade et al. 1995; Hurt and Robertson 1998; Henning?eld et al. 2006; Henning?eld and Hartel 1999; Larson et al. 1961).

Nicotine --Physiological effect. --- Nicotine. --- Psychopharmacology. --- Nicotine --- Psychopharmacology --- Tobacco Use Disorder --- Methods --- Pharmacology --- Biological Science Disciplines --- Pyridines --- Substance-Related Disorders --- Solanaceous Alkaloids --- Behavioral Sciences --- Psychiatric Somatic Therapies --- Investigative Techniques --- Diseases --- Heterocyclic Compounds, 1-Ring --- Behavioral Disciplines and Activities --- Alkaloids --- Natural Science Disciplines --- Mental Disorders --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Occupations --- Psychiatry and Psychology --- Heterocyclic Compounds --- Disciplines and Occupations --- Chemicals and Drugs --- Pharmacy, Therapeutics, & Pharmacology --- Toxicology & Public Health --- Public Health --- Health & Biological Sciences --- Physiological effect --- Physiological effect. --- Behavioral pharmacology --- Drugs --- Psychotropic effects --- Medicine. --- Neurosciences. --- Pharmacology. --- Psychiatry. --- Neuropsychology. --- Biomedicine. --- Pharmacology/Toxicology. --- Chemotherapy --- Psychotropic drugs --- Pyridine --- Tobacco --- Tobacco products --- Toxicology. --- Psychology, clinical. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Chemicals --- Medicine --- Poisoning --- Poisons --- Toxicology --- Neurophysiology --- Psychophysiology --- Drug effects --- Medical pharmacology --- Pharmacy