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Almost exactly ten years ago, two young physicians joined me at the University of Oklahoma for the study of dermatopathology: Stephen C. Somach, a brilliant dermatologist-scholar from Cleveland, who was also a highly accomplished cellist, and Michael B. Morgan, an effervescent, newly minted pathologist from Florida, who was brimming with energy, curiosity, and zeal and was also spo- ing water skiis and a red Porsche! Bruce R. Smoller, whose impressive erudition is universally acknowledged, I met during a Residency Review committee visit to Stanford some ?fteen years ago. Each of these men has made original cont- butions to the dermatopathology literature as well as to patient care in the cli- cal setting. Their publications have broadened our understanding of the biologic behavior of pigmented lesions, cutaneous lymphomas, vascular lesions, and soft tissue tumors. It is indeed a pleasure to welcome their volume, Deadly Der- tologic Diseases, a unique and stimulating outcome of their enthusiastic collaboration. Deadly Dermatologic Diseases discusses a wide variety of entities–neoplastic, vascular, infectious, metabolic–each of which may eventuate in death of the patient. In addition, numerous tumors and dermatoses frequently associated with internal malignancies are reviewed. High-quality histologic photomic- graphs and clinical pictures accompany many of the discussions. A unique initial summary page facilitates the reading of each presentation. Recent relevant genetic and biochemical ? ndings in every chapter were particularly helpful to this reader.

Skin --- Diseases. --- Histopathology. --- Cutaneous diseases --- Dermatoses --- Dermatology --- Dermatology. --- Pathology. --- Emerging infectious diseases. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Infectious diseases.

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Tropical emerging diseases pose a significant risk for the circulation of old and new pathogens in areas previously unknown, also implying the possibility of new morbidities and mortalities and new consequences for naïve populations. Globalization, migration and travel are key factors for tropical diseases, and represent the need for integration of tropical medicine, travel medicine and epidemiology in the understanding of such complex situations. Neglected tropical diseases such as leprosy or Chagas disease, arboviral diseases, HIV, Ebola, and arenaviral infections are just a few examples. This book tries to update significant epidemiological and clinical research in many aspects with a multinational perspective.

Emerging infectious diseases. --- Tropical medicine. --- Diseases, Tropical --- Hygiene, Tropical --- Medicine --- Public health, Tropical --- Sanitation, Tropical --- Tropical diseases --- Medical climatology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Public Health --- Global Health --- Health Sciences

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"Recent high-profile outbreaks, such as Ebola and Zika, have illustrated the transnational nature of infectious diseases. Countries that are most vulnerable to such outbreaks might be higher priorities for technical support. RAND created the Infectious Disease Vulnerability Index to help U.S. government and international agencies identify these countries and thereby inform programming to preemptively help mitigate the spread and effects of potential transnational outbreaks. The authors employed a rigorous methodology to identify the countries most vulnerable to disease outbreaks. They conducted a comprehensive review of relevant literature to identify factors influencing infectious disease vulnerability. Using widely available data, the authors created an index for identifying potentially vulnerable countries and then ranked countries by overall vulnerability score. Policymakers should focus on the 25 most-vulnerable countries with an eye toward a potential "disease belt" in the Sahel region of Africa. The infectious disease vulnerability scores for several countries were better than what would have been predicted on the basis of economic status alone. This suggests that low-income countries can overcome economic challenges and become more resilient to public health challenges, such as infectious disease outbreaks"--

Emerging infectious diseases --- Communicable diseases --- Diseases --- Epidemics --- Disease outbreaks --- Outbreaks of disease --- Pandemics --- Pestilences --- Disease risk factors --- Risk factors in diseases --- Biosecurity --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Prevention. --- Risk factors. --- Political aspects. --- Outbreaks

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It is with great pleasure that we introduce the first volume of Birkhäuser Advances in Infectious Diseases. This book series focuses on relevant and trending topics in microbiology and infectious diseases with emphasis on emerging pathogens and related diseases. This interdisciplinary series presents latest advances and new approaches in molecular biology as well as insights into human and veterinary clinical medicine. Furthermore, matters in epidemiology, disease management, hygiene and prevention of infectious diseases are discussed. Emerging or novel pathogens are a grand challenge in medical science. Therefore, we focused the first volume of this series on the outbreak of SARS. The advent of SARS is a threat for people around the globe. Our modern technologies in communication and mobility have figuratively transformed the world into a village. This traffic, however, represents a new opportunity to spread diseases, particularly such of infectious nature from tiny villages throughout the entire world. In-depth knowledge of a novel pathogen's characteristics will help to manage or event prevent pandemias.

SARS (Disease) --- Coronavirus infections. --- Coronaviruses. --- Common cold viruses --- Coronaviridae --- Nidoviruses --- Coronavirus diseases --- Virus diseases --- Acute respiratory syndrome, Severe --- Respiratory syndrome, Severe acute --- Severe acute respiratory syndrome --- Coronavirus infections --- Respiratory infections --- Syndromes --- Emerging infectious diseases. --- Microbiology. --- Infectious Diseases. --- Medical Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Infectious diseases. --- Medical microbiology.

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Complement has long been regarded as a pivotal effector arm of the innate im-mune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspec-tive. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory cir-cuits. In this respect, scientists from around the world convened at the Third Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 5–10, 2005), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the "novel" functions of complement, pathophysiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference.

Complement (Immunology) --- Blood proteins. --- Plasma proteins --- Serum proteins --- Blood plasma --- Proteins --- Serum --- Alexin --- Complements (Immunity) --- Blood proteins --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Pathology. --- Infectious Diseases. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Infectious diseases.