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Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models

Rheumatoid arthritis --- Rheumatoid arthritis. --- Animal models.

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

rheumatoid arthritis --- synoviocyte --- inflammation --- aggressor --- immunomodulatory functions

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"In Fierce and Delicate, she looks back on the often confused and driven self she had been shaped into and finds beauty in the small roles she performed. When, inevitably, Nicholson moved on from dancing, severed from her first love by illness, she discovered that she retained the lyricism and narrative of ballet itself as she negotiated life with rheumatoid arthritis. An intentionally fractured memoir-in-essays, Fierce and Delicate navigates traditional geographies-South Florida, Northern Michigan, New York City, Milwaukee, West Virginia-and also geographies of the body. It is a book about the world of professional dance and also about living with chronic disease, about being shattered yet realizing the power to assemble oneself again, in a new way"--

Rheumatoid arthritis --- Ballet dancers --- Patients --- Nicholson, Renee K. --- United States.

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Atlas of Rheumatoid Arthritis is a high-quality educational initiative, written by leaders in the field of rheumatology, containing a collection of approximately 150 relevant images, with extended descriptive captions and a comprehensive bibliography. The Atlas of Rheumatoid Arthritis will provide clinicians with a visual guide to rheumatoid arthritis, focusing on assessment, diagnosis and treatment, including newer research into the signalling pathways involved in the pathogenesis of RA, before focusing on the treatment of RA. Rheumatoid arthritis (RA) is the most common and most serious of the inflammatory arthritic disorders, and it dominates clinical rheumatological practice. Effective, early treatment is vital as this can slow the course of the disease and reduce joint damage. RA is usually treated using disease-modifying anti-rheumatic drugs (DMARDs), most commonly methotrexate. The newest treatments target the disease-causing immune elements specifically and directly.

Medicine & Public Health. --- Rheumatology. --- Medicine. --- Médecine --- Rhumatologie --- Rheumatoid arthritis -- Diagnosis. --- Rheumatoid arthritis -- Treatment. --- Rheumatoid arthritis. --- Medicine --- Health & Biological Sciences --- Musculoskeletal System Diseases --- Rheumatoid arthritis --- Joints --- Diagnosis. --- Treatment. --- Articulations (Anatomy) --- Diarthrodial joints --- Synovial joints --- Adjuvant arthritis --- Arthritis deformans --- Arthrosis deformans --- Rheumatic gout --- Musculoskeletal system --- Arthritis --- Autoimmune diseases --- Blood hyperviscosity syndrome --- Rheumatism --- Internal medicine --- Connective tissues --- Diseases

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Sjogren's syndrome. --- Gougerot-Sjogren's syndrome --- Sicca syndrome --- Keratoconjunctivitis sicca --- Rheumatoid arthritis --- Salivary glands --- Diseases