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Population genetics has made great strides in applying statistical analysis and mathematical modeling to understand how genes mutate and spread through populations over time. But real populations also live in space. Streams, mountains, and other geographic features often divide populations, limit migration, or otherwise influence gene flow. This book rigorously examines the processes that determine geographic patterns of genetic variation, providing a comprehensive guide to their study and interpretation. Geographical Genetics has a unique focus on the mathematical relationships of spatial statistical measures of patterns to stochastic processes. It also develops the probability and distribution theory of various spatial statistics for analysis of population genetic data, detailing exact methods for using various spatial features to make precise inferences about migration, natural selection, and other dynamic forces. The book also reviews the experimental literature on the types of spatial patterns of genetic variation found within and among populations. And it makes an unprecedented strong connection between observed measures of spatial patterns and those predicted theoretically. Along the way, it introduces readers to the mathematics of spatial statistics, applications to specific population genetic systems, and the relationship between the mathematics of space-time processes and the formal theory of geographical genetics. Written by a leading authority, this is the first comprehensive treatment of geographical genetics. It is a much-needed guide to the theory, techniques, and applications of a field that will play an increasingly important role in population biology and ecology.
Medical geography. --- Population geography. --- Earth Sciences --- Geographical distribution of diseases --- Geographical pathology --- Geography, Medical --- Geomedicine --- Medical topography --- Pathology, Geographic --- Topography, Medical --- Population genetics. --- Demography --- Human geography --- Genetics --- Heredity --- Diseases --- Geography --- Medical climatology --- World health --- Geographical distribution --- Medical geography --- Population genetics --- Population geography --- 575.17 --- 575.17 Population genetics. Genetic processes in populations --- Population genetics. Genetic processes in populations --- Génétique des populations --- Géographie médicale --- Géographie de la population
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Genetic Processes --- Medicine --- Molecular Biology --- Medical genetics --- Pathology, Molecular --- Molecular biology --- Génétique médicale --- Pathologie moléculaire --- Biologie moléculaire --- Periodicals. --- Périodiques --- Molecular Biology. --- Genetic Processes. --- Medicine. --- Medical genetics. --- Molecular biology. --- Pathology, Molecular. --- Health Sciences --- Life Sciences --- Pathology --- Biology --- molecular medicine --- molecular pathology --- genetic processes --- regenerative medicine --- systems medicine --- molecular biology --- Medical Specialities --- Medical Specialties --- Medical Specialty --- Specialities, Medical --- Specialties, Medical --- Specialty, Medical --- Medical Speciality --- Speciality, Medical --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Genetic Phenomena --- Molecular pathology --- Physiology, Pathological --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Genetic disorders --- Genetic aspects --- Biologie moléculaire --- Health Workforce --- Genetics --- Human medicine --- Genetic Phenomena. --- cell biology --- translational medicine
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Epigenesis --- Epigenesis, Genetic. --- Genetics, Medical. --- Epigenesis. --- Epigenesis, Genetic --- Genetics, Medical --- Human Genetics --- Medical Genetics --- Genetics, Human --- Epigenetic Process --- Epigenetics Processes --- Epigenetic Processes --- Genetic Epigenesis --- Process, Epigenetic --- Processes, Epigenetic --- Processes, Epigenetics --- genetic processes --- epigenetic therapy --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- DNA Methylation --- Embryology --- Evolution (Biology) --- Genetics --- Genetics & Genomics. --- Health Sciences --- Epigenome --- Genetic Phenomena. --- Genetics. --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Genetic Processes --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Molecular Biology --- Genetic Structures --- Genetic Phenomena --- Human medicine
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Dan Lieberman has written an innovative, exhaustively researched and carefully argued book dealing with the evolution of the human head. In it he addresses three interrelated questions. First, why does the human head look the way it does? Second, why did these transformations occur? And third, how is something as complex and vital as the head so variable and evolvable? This book addresses these questions in three sections. The first set of chapters review how human and ape heads grow, both in terms of individual parts (organs and regions) and as an integrated whole. The second section reviews how the head performs its major functions: housing the brain, chewing, swallowing, breathing, vocalizing, thermoregulating, seeing, hearing, tasting, smelling, and balancing during locomotion. The final set of chapters review the fossil evidence for major transformations of the head during human evolution from the divergence of the human and ape lineages through the origins of Homo sapiens. These chapters use developmental and functional insights from the first two sections to speculate on the developmental and selective bases for these transformations.
Human anatomy --- Evolution. Phylogeny --- Head --- Human evolution. --- Biological Evolution. --- Evolution. --- Growth. --- growth & development. --- Human evolution --- Genetic Processes --- Biological Processes --- Physiological Processes --- Body Regions --- Genetic Phenomena --- Physiological Phenomena --- Biological Phenomena --- Anatomy --- Phenomena and Processes --- Biological Evolution --- Growth and Development --- Human Anatomy & Physiology --- Health & Biological Sciences --- Evolution --- Growth --- Evolution (Biology) --- Physical anthropology --- Evolutionary psychology --- Human beings --- Figure drawing --- Skull --- Origin
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One of the most controversial contemporary debates on the concept of health is the clash between the views of naturalists and normativists. This debate has fueled many of the, often very acrimonious, disputations arising from the claims of health, disease and disability activists and charities and the public policy responses to them. In responding to this debate, Ananth both surveys the existing literature, with special focus on the work of Christopher Boorse, and argues that a naturalistic concept of health, drawing on evolutionary considerations associated with biological function, homeostas
Philosophy of science --- Evolution (Biology) --- Health --- Medicine --- Naturalism. --- Normativity (Ethics) --- Health. --- Philosophy, Medical. --- Ethical Theory. --- Evolution. --- Philosophy. --- Naturalism --- Biological Evolution --- Ethical Theory --- Philosophy, Medical --- Biological Processes --- Population Characteristics --- Genetic Processes --- Ethics --- Philosophy --- Humanities --- Health Care --- Genetic Phenomena --- Biological Phenomena --- Phenomena and Processes --- Medical Ethics & Philosophy --- Health & Biological Sciences --- Evolution (Biology). --- Normativity (Ethics).
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Genomic imprinting refers to a recently discovered phenomenon in which the expression pattern of an allele depends on whether that allele was inherited from the mother or the father. This difference in expression strategy correlates with differences in the epigenetic state of the two alleles. These epigenetic differences include DNA methylation at CpG dinucleotides, as well as modifications on the histones associated with the locus. In the simplest possible cases, the promoter region of the imprinted gene is methylated during oogenesis, but not spermatogenesis (or vice versa). This methylation (and its accompanying histone modifications) results in inactivation of the modified allele. Of course, most imprinted genes do not fall into this simplest case. The goal of this book is neither to provide a basic introduction to imprinting, nor to provide a comprehensive survey of the current state of the field (which would necessarily span multiple books). Rather, the book covers on some of the more recent advances, with the goal of drawing attention to some of the emerging subtleties and complexities associated with imprinted genes.
Biomedicine. --- Human Genetics. --- Medicine. --- Human genetics. --- Médecine --- Génétique humaine --- Genomic imprinting. --- Genomic imprinting --- Genomic Imprinting --- Epigenesis, Genetic --- Gene Expression Regulation --- Genetic Processes --- Genetic Phenomena --- Phenomena and Processes --- Genetics --- Pathology --- Biology --- Medicine --- Health & Biological Sciences --- Gene imprinting --- Genetic imprinting --- Genome imprinting --- Imprinting, Genomic --- Parental imprinting (Genetics) --- Heredity, Human --- Human biology --- Physical anthropology --- Clinical sciences --- Medical profession --- Life sciences --- Medical sciences --- Physicians --- Gene expression
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Genetic Phenomena --- Genetics --- Génétique --- Periodicals. --- Research --- Periodicals --- Périodiques --- Recherche --- Genetic Phenomena. --- Genetics. --- Research. --- genetics --- genomics --- heredity --- Genetic research --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Genetic Processes --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Molecular Biology
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Genetic Phenomena. --- Genome. --- Genomics. --- Genomics --- Génomique --- Periodicals. --- Périodiques --- Genetics & Genomics. --- Genome research --- Genomes --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Genetic Processes --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Research --- Molecular genetics --- Human Genome Project --- Genome --- Genes --- Proteome --- Molecular Biology --- Comparative Genomics --- Comparative Genomic --- Genomic, Comparative --- Genomics, Comparative --- genomics --- Genetic Phenomena
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Genetics --- Genetic Phenomena --- Génétique --- Periodicals. --- Périodiques --- Genetics. --- Genetic Phenomena. --- genetics --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Genetic Processes --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Molecular Biology --- Genetic Structures
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Building the Most Complex Structure on Earth provides readers with a basic biological education an easy and understandable introduction into a new epigenetic theory of development and evolution. This is a novel theory that describes the epigenetic mechanisms of the development and evolution of animals and explains the colossal evolution and diversification of animals from a new post-genetic perspective. Modern biology has demonstrated the existence of a common genetic toolkit in the animal kingdom, but neither the number of genes nor the evolution of new genes is responsible for the
Epigenetics --- Evolution (Biology) --- Developmental biology --- Genetic Processes --- Gene Expression Regulation --- Genomics --- Biological Processes --- Computational Biology --- Genetics --- Genetic Phenomena --- Biological Phenomena --- Biology --- Phenomena and Processes --- Biological Science Disciplines --- Natural Science Disciplines --- Disciplines and Occupations --- Biological Evolution --- Epigenomics --- Epigenesis, Genetic --- Health & Biological Sciences --- Evolution --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Epigenetics. --- Developmental biology.
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