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This book presents a survey of recent developments in protein biochemistry. Top researchers in the field of protein biochemistry describe modern methods to address the challenges of protein purification by three-phase partitioning, and their folding and degradation by the functions of chaperones. The significance of peptide purity for fibril formation is addressed as well as the use of target oriented peptide arrays in palliative approaches in mucoviszidose. The design and application of protein epitope mimetics just as the structural resolving of the misfolding of various mutant proteins in s

Proteins --- Proteomics. --- Molecular biology --- Protein biosynthesis --- Protein synthesis --- Analysis. --- Synthesis. --- Metabolism --- Analytical Methods. --- Biochemistry. --- Proteins.

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De nombreux problèmes scientifiques et techniques ne peuvent pas être résolus analytiquement et nécessitent des calculs numériques. L’objectif de cet ouvrage est de proposer des méthodes concrètes en utilisant des logiciels faciles d’accès (essentiellement le logiciel gratuit Scilab mais aussi Mapple). Le livre se veut pratique, y compris sur des thèmes qui peuvent entraîner des développements compliqués. Cette nouvelle édition renforce les atouts qui firent le succès de la précédente : seules les bases mathématiques nécessaires au traitement de la partie numérique sont introduites. De nombreux exercices d’application sont proposés dans une progression judicieuse pour faciliter l’acquisition des compétences. Le livre reprend les thèmes usuels, de l’interpolation aux vecteurs propres. D’autres chapitres plus originaux sont proposés : représentation graphique, calcul et approximation de fonctions, représentation de grandeurs physiques, méthode des éléments finis pour la résolution d’équations aux dérivées partielles, probabilités et erreurs… Le lecteur trouvera ici une belle variété d’exercices et de projets pour s’approprier les méthodes ; il utilisera cet ouvrage comme un recueil de recettes numériques pour les problèmes qu’il rencontre. Le livre est la porte d’entrée d’un site web (https://www.grenoble-sciences.fr/pap-ebooks/grivet/home?destination=node/140) dans lequel des solutions d’exercices, des programmes en Scilab, des projets et même des publications permettent de progresser, quel que soit son niveau de départ.

Mathematics. --- Math --- Science --- Analytical methods --- Data analysis --- Statistical methods --- Models --- Data processing --- engineering --- computer applications --- Analyse numérique. --- Numerical analysis

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Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved; the general properties of chemicals and biologic systems as they influence the occurrence of detrimental biologic effects; the methods used to demonstrate these effects; and the basis for clinical diagnosis and therapy of harmful effects of chemicals on humans. Individual examples are used to demonstrate each of the principles under discussion.Th

Toxicology. --- toxic substances --- Immunology --- toxicity --- Toxicology --- therapy --- Biotechnology --- Measurement --- Analytical methods --- Pollution --- public health --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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analytical methods --- quality control --- validation --- drug content --- stability --- chromatography --- Pharmaceutical chemistry --- Chimie pharmaceutique --- Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry

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In recent years electrochemistry has undergone a revival, particularly in its analytical applications. As a non- destructive method, with rapid response times and low detection levels, polarography is now in competition with other methods of analysis, such as spectrophotometry and AAS.

fysicochemie --- voltametrie --- Electrochemical analysis --- Polarography --- Voltammetry --- Chemistry, Analytic --- Polarographie --- Chimie analytique --- Programmed instruction --- Enseignement programmé --- Technique analytique --- Analytical methods --- Analytische chemie: electrochemie --- 543.253 --- -Polarography --- -Voltammetry --- -analytische chemie --- polarografie --- 543.55 --- analytische chemie (scheikunde) --- elektrochemische analyse --- voltammetrie --- Polarografie --- 543.1 --- Voltametrie --- Analysis, Chemical --- Analytical chemistry --- Chemical analysis --- Metallurgical analysis --- Mineralogy, Determinative --- Voltametry --- Polarograph and polarography --- Polarographic analysis --- Basic Sciences. Chemistry --- Programmed instruction. --- Analytical Chemistry --- Analytical Chemistry. --- 543.253 Polarographic analysis --- Enseignement programmé --- analytische chemie --- Analytic chemistry --- Chemistry --- Voltammetry - Programmed instruction --- Chemistry, Analytic - Programmed instruction --- Polarography - Programmed instruction --- Open learning --- Methode potentiometrique --- Polarography. --- Voltammetry. --- Analytical methods. --- Voltamétrie --- Enseignement programmé.