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Statins : understanding clinical use
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ISBN: 9781437713077 1437713076 0721603807 9780721603803 9780721603803 Year: 2004 Publisher: [Place of publication not identified] Saunders


Book
Chitin : fulfilling a biomaterials promise
Author:
Year: 2001 Publisher: [Place of publication not identified] Elsevier Science Ltd


Book
International Review of Research in Mental Retardation: Neurotoxicity and Developmental Disabilities
Authors: --- ---
Year: 2005 Publisher: [Place of publication not identified] Academic Press Imprint


Book
Hormones, santé publique et environnement
Authors: ---
Year: 2008 Publisher: EDP SCIENCES

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Abstract

La recherche en endocrinologie a été un des points forts de la biologie française au cours des dernières décennies. Elle joue un rôle majeur sur le plan fondamental où, en dehors de son intérêt propre, elle sert de modèle à la compréhension des mécanismes généraux de signalisation. En outre, elle débouche sur certains des problèmes les plus préoccupants de santé publique, donnant lieu à de très importantes approches pharmacologiques et thérapeutiques. L'objet de ce rapport est d'évoquer les plus importants de ces problèmes, situés à l'interface des sciences médicales et des sciences de la société. du point de vue strictement médical, quatre questions se posent avec une acuité croissante : les relations entre hormones et cancers, le traitement substitutif de la ménopause, la contraception hormonale au long terme et l'influence de certaines hormones sur le développement de l'obésité et du diabète de type 2. Un autre sujet important concerne le vieillissement, conçu comme un ensemble complexe de facteurs biologiques, cognitifs, sociaux et finalement sociétaux. Un aspect, plus technique mais également de grande importance, concerne les perturbateurs hormonaux, des produits chimiques qui peuvent modifier de façon indésirable la production de certaines hormones. Un dernier aspect concerne l'utilisation des hormones hors de la médecine, notamment chez les animaux comestibles. L'ambition de ce rapport est de donner l'arrière-plan scientifique permettant de comprendre les mécanismes biologiques impliqués dans ce groupe de problèmes majeurs de santé publique. Les voies de recherches actuelles sont résumées, les voies futures sont indiquées et des recommandations sont présentées. Les principaux partenaires institutionnels intervenant dans chaque cas sont cités. Lorsqu'elles existent, les controverses scientifiques et quelquefois politico-médiatiques sont explicitées. L'ouvrage traite les questions suivantes: 1-Les cancers hormonodépendants: Les mécanismes de base, les cancers du sein, les cancers de la prostate. 2-Le traitement substitutif de la ménopause. 3-L'obésité, les diabète de type 2. 4-Les hormones et le vieillissement. 5-Les perturbateurs hormonaux 6-Les hormones en Zootechnie.


Book
The Botany and Chemistry of Hallucinogens
Authors: ---
ISBN: 0398081867 Year: 1980 Publisher: Springfield : Charles C Thomas,

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By Richard Evans Schultes, Harvard University, Cambridge, Massachusetts, and Albert Hofmann, Basel, Switzerland. With Forewords by I. Newton Kugelmass and Henrich Kluver. The Second Edition of this book encompasses all of the advances that have been made in this field since publication of the original text. Newly discovered hallucinogenic plants have been incorporated into the discussions along with new information on some well-known drugs. The authors continue to focus on the botany and chemistry of hallucinogens, although they also consider ethnobotanical, historical, pharmacological and psy

Adverse syndromes and psychiatric drugs : a clinical guide
Authors: --- ---
ISBN: 0191769789 1281015784 1423700821 9781423700821 9780191769788 9780198527480 0198527489 9786611015787 6611015787 0198527489 9781281015785 Year: 2004 Publisher: Oxford : Oxford University Press,

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Abstract

Pharmacotherapy is an important part of the treatment of major phychiatric disorders. Although psychiatric drugs can have benefits for patients, adverse syndromes are common, causing distress for patients. This book will help psychiatrists, GPs pharmacists and nurses manage adverse syndromes associated with psychiatric drugs.

Basic medical endocrinology
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ISBN: 1281053341 9786611053345 0080488366 0122904214 9780122904219 9780080488363 Year: 2003 Publisher: San Diego, Calif. : Academic Press,

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Basic Medical Endocrinology, Third Edition provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. The discussion focuses on molecular and cellular aspects of hormone production and action firmly rooted in the context of integrative physiology. Topics are approached from the perspective of a physiologist with four decades of teaching experience. This book is richly illustrated with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. Each of the thir


Book
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
Authors: --- --- ---
ISSN: 21969914 ISBN: 1461491347 1461491355 Year: 2014 Publisher: New York, NY : Springer New York : Imprint: Humana,

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There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development.


Book
Bioactive materials in medicine : design and applications
Authors: --- ---
ISBN: 0857092936 1845696247 9780857092939 9781845696245 Year: 2011 Publisher: Cambridge : Woodhead Pub.,

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Abstract

Bioactive materials play an increasingly important role in the biomaterials industry, and are used for a range of applications, including artificial organs, drug delivery systems, nanomedicine, and biosensors. Bioactive materials in medicine reviews the current status and ongoing development of bioactive materials for medical applications.Following an introduction to bioactive materials in medicine, part one covers the process of designing bioactive materials, including chapters on molecular design, nanotechnology, and tissue engineering. Part two focuses on the different applications

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