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Ferguson, Wes --- Travel --- Blanco River (Tex.) --- History. --- Description and travel.

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

artificial intelligence --- NGS - next generation sequencing --- non-invasive prenatal testing (NIPT) --- WGS - whole-genome sequencing --- WES - whole-exome sequencing

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This book describes the latest research on the geological, geochemical, geochronological, biological, and geomorphic evolution of the unique and relatively pristine landscape of the Cape Mountains and the Karoo Basin, a region in South Africa that is currently being targeted for shale gas exploration and development. With up-to-date graphics, maps, drill-core and seismic data, it offers the latest observations and synthesis, and highlights areas of ongoing research. The work presented also considers a wider connection of the Cape-Karoo system to other basins in Central Gondwana, including South America, thus following in the footsteps of A. L. du Toit. Clearly, there is still much to be learned before shale gas development can be considered, and this book provides some timely perspectives.

Earth sciences. --- Fossil fuels. --- Historical geology. --- Structural geology. --- Geobiology. --- Earth Sciences. --- Structural Geology. --- Historical Geology. --- Biogeosciences. --- Fossil Fuels (incl. Carbon Capture). --- Mountains --- Karoo Basin (Lesotho and South Africa) --- Geotectonics --- Structural geology --- Tectonics (Geology) --- Fossil energy --- Geosciences --- South Africa. --- Western Cape (South Africa) --- History. --- Intshona Koloni (South Africa) --- Province of the Western Cape (South Africa) --- Province of Western Cape (South Africa) --- Provinsie Wes-Kaap (South Africa) --- Wes-Kaap (South Africa) --- Cape of Good Hope (South Africa) --- Africa, South --- Geology, Structural. --- Geology. --- Geognosy --- Geoscience --- Earth sciences --- Natural history --- Physical geology --- Fuel --- Energy minerals --- Biology --- Biosphere --- Geology

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Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed “nonobstructive azoospermia” (NOA) to differentiate it from the less severe form of azoospermia caused by the obstruction of the seminal tract (obstructive azoospermia—OA), the latter affecting the remaining one-third of cases. Managing patients with NOA is challenging due to the severity of spermatogenic dysfunction and the lack of medical treatments, with surgical retrieval of testicular sperm being the only way of enabling some of these patients to father their own biological children. In-depth clinical knowledge is key for supporting clinical reasoning and decision making when counselling patients with NOA, and surgical skill is required to maximize the outcome of surgical procedures that aim to retrieve testicular sperm. The present book is a collection of scientific papers published in a Special Issue of the Journal of Clinical Medicine, authored by some of the most influential researchers in the field. The Special Issue, and thus also this book, were conceived to provide early career reproductive urologists and endocrinologists with an update of the scientific evidence in the field, together with surgical tips.

nonobstructive azoospermia --- micro-TESE --- FSH treatment --- hormonal treatment --- testosterone level --- microdissection testicular sperm extraction --- non-obstructive azoospermia --- management --- infertility --- intracytoplasmic sperm injection --- testicular azoospermia --- sperm selection --- sperm --- cryopreservation --- in vitro maturation --- azoospermia --- diagnosis --- male infertility --- spermatogenic failure --- testis biopsy --- sperm retrieval --- genetic testing --- endocrine evaluation --- review --- hypogonadism --- Sertoli cell-only syndrome --- testicular spermatozoa --- processing --- microfluidics --- new technologies --- genetics --- exome --- WES --- Y chromosome --- cancer --- NOA --- genes --- general health --- ICSI --- offspring health --- microTESE --- prediction model --- n/a

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West Virginia --- West Virginia. --- W. Va. --- WV --- West Va. --- W.V. (West Virginia) --- W. Virg. --- State of West Virginia --- Wes-Virginië --- Wescht Virginia --- Virchinia Occidental --- Estato de Virchinia Occidental --- Virginia du Ponant --- Virxinia Occidental --- Kuarahyresẽ Virginia --- Qärbi Virciniya --- Штат Заходняя Вірджынія --- Shtat Zakhodni︠a︡i︠a︡ Virdz︠h︡ynii︠a︡ --- Заходняя Вірджынія --- Zakhodni︠a︡i︠a︡ Virdz︠h︡ynii︠a︡ --- Западна Вирджиния --- Zapadna Virdzhinii︠a︡ --- Щат Западна Вирджиния --- Shtat Zapadna Virdzhinii︠a︡ --- Zapadna Virginia --- Virginia ar C'hornaoueg --- Virgínia de l'Oest --- Virgínia Occidental --- Анăç Вирджини --- Anăś Virdzhini --- Virginia --- Virginia (Reorganized government : 1861-1863) --- Economic conditions.