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Taking advantage of the many major advances that have occurred since their groundbreaking first edition was published, William B. Coleman and Gregory J. Tsongalis have updated and expanded their highly praised tutorial guide to molecular diagnostic techniques to include not only improved traditional methods, but also totally new molecular technologies, some not yet in routine use. The authors offer cutting-edge molecular diagnostics for genetic disease, human cancers, infectious diseases, and identity testing, as well as new insights into the question of quality assurance in the molecular diagnostics laboratory. Additional chapters address other technologies found in the clinical laboratory that are complementary to molecular diagnostic methodologies, and also discuss genetic counseling and the ethical and social issues involved with nucleic acid testing. Authoritative and state-of-the-art, Molecular Diagnostics: For the Clinical Laboratorian, 2nd Edition is the essential textbook of choice for anyone working in molecular diagnostics and who wants to remain current with this rapidly changing field.

Chemistry, Clinical -- Methods. --- Molecular diagnosis. --- Pathology, Molecular. --- Technology, Medical. --- Molecular diagnosis --- Pathology, Molecular --- Chemistry --- Investigative Techniques --- Biochemistry --- Genetics --- Technology --- Biology --- Biological Science Disciplines --- Technology, Industry, and Agriculture --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Natural Science Disciplines --- Technology, Industry, Agriculture --- Disciplines and Occupations --- Genetic Techniques --- Molecular Biology --- Clinical Laboratory Techniques --- Biomedical Technology --- Chemistry, Clinical --- Medicine --- Health & Biological Sciences --- Pathology --- Molecular pathology --- Diagnosis --- Molecular diagnostics --- Molecular aspects --- Medicine. --- Human genetics. --- Laboratory medicine. --- Pathology. --- Microbiology. --- Medicine & Public Health. --- Laboratory Medicine. --- Human Genetics. --- Molecular biology --- Physiology, Pathological --- Medical laboratories. --- Microbial biology --- Microorganisms --- Heredity, Human --- Human biology --- Physical anthropology --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis

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As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology Teaches from the perspective of "integrative systems biology".

Pathology, Molecular. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Molecular pathology --- Molecular biology --- Physiology, Pathological