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Rheumatoid Arthritis (RA) represents a complex disease where the inheritable component has been estimated to be up to 60%. This PIR volume deals with the genetic basis and regulation of rheumatic diseases. The first part of the book describes genetic studies on rheumatic diseases. The second part deals with the shared heredity of rheumatic diseases, e.g., RA, lupus and ankylosing spondylitis. The third part of the volume describes tools for analysing genetic complexity, ranging from animal models to new molecular tools. The volume is essential reading for researchers and clinicians from rheumatology, inflammation research, immunology, and cell and molecular biology. .

Rheumatism --- Genetic aspects. --- Rheumatic diseases --- Collagen diseases --- Musculoskeletal system --- Diseases --- Rheumatology. --- Immunology. --- Human genetics. --- Cytology. --- Human Genetics. --- Cell Biology. --- Internal medicine --- Connective tissues --- Joints --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Immunobiology --- Life sciences --- Serology --- Cell biology.

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Autoantibody --- Pemphigus --- Pemphigoid --- Arthritis --- systemic lupus erythematosus --- autoimmune neurological disease --- Pathogenesis --- Biomarker. Diagnosis --- Treatment