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cancer detection --- immunology --- carcinogenesis --- stem cell biology --- pharmacology --- cancer prevention
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Oncology is a field characterized as “medicine of high complexity” and cancer is generally regarded as a complex system. Therefore, it cannot be classified and treated according only to its biology. Even though research on the biology of cancer has increased and more studies have been published, the related sociological, political and economic dimensions, as well as mathematical models that predict whether this condition will take one course or another, have often been neglected. The Invisible Hand of Cancer—The Complex Force of Socioeconomic Factors in Oncology Today unfolds the variables behind the biological disease, exploring the social aspects and presenting cancer as a model inside of the Complexity Theory. Cancer is a generic word for more than 200 diseases. In a wider view of cancer treatment, the various factors of cancer interact in multiple ways and it is a difficult task to identify and understand all the possible combinations in this system. All these variables and how they interact can be defined as the invisible hand of cancer. This book does not intend to be an exhaustive analysis of these aspects. It is a door being opened to the cancer research journey, along the years and beyond its biology. It will also discuss how social behavior can interfere in the evolution of cancer treatment, as a result of society’s way of thinking and choices, thus the importance of truly addressing cancer as an intricate system and a public health issue. After the success of my children’s books about cancer (Chubby’s Tale: The true story of a teddy bear who beat cancer, Bald is Beautiful: A letter for a fabulous girl, Cancer Daily Life, and What is Cancer?: A book for kids), I have developed a passion for writing about science in a simple way for non-scientist readers. I have also worked to build a career as a writer, communicating with patients, advocates, and oncology and pediatric oncology professionals, mostly on Twitter. Everyone knows someone who has or had cancer, so more and more popular science books on this topic are becoming bestsellers. This book is directed to a general audience and follows scientific standards, encompassing high-quality data, but in an easy-to-read format. Furthermore, it will raise awareness and show how simple actions such as not judging patients and not spreading false popular beliefs can contribute to achieve a new milestone in the cancer journey.
Oncology. --- Cancer --- Cancer Therapy. --- Cancer Prevention. --- Treatment. --- Prevention.
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Cancer care delivery refers to the multiple layers of the health care system that interact to affect outcomes for patients with cancer and the quality of that care. The factors included in the care delivery system that potentially alter outcomes include social dynamics, financing systems, organizational structures and processes, health technologies, provider and individual behaviors. Because women’s health care has its own unique challenges, the intersection between cancer care delivery and women’s health is to be examined in this Frontiers in Oncology issue. The unique opportunities and challenges of improving the health care system for women with breast and gynecologic cancers are to be explored in depth. We will visit many topics of cancer care delivery with the unique perspective geared towards the care of women’s malignancies.
survivorship --- health care delivery --- cancer prevention --- ovarian cancer --- endometrial cancer --- gynecologic cancer --- breast cancer --- cervical cancer
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Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer provides a current perspective on the epidemiology of head and neck cancer. Cancers of the oral cavity, pharynx, and larynx comprise an important group of tumors with diverse international patterns of incidence and mortality, established associations with tobacco and alcohol use, the human papilloma virus, and potential determinants of genetic susceptibility. Because of these factors, head and neck cancer offers a unique insight into mechanisms of cancer initiation and progression and gene-exposure interaction. This book brings together the latest epidemiologic and molecular genetic evidence regarding the patterns of occurrence and causes of head and neck cancer. In addition, Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer considers approaches to chemoprevention, and incorporates a multidisciplinary perspective including salient clinical, pathologic, molecular, and epidemiologic contributions.
Head -- Cancer -- Epidemiology. --- Head -- Cancer -- Pathogenesis. --- Head -- Cancer -- Prevention. --- Neck -- Cancer -- Epidemiology. --- Neck -- Cancer -- Pathogenesis. --- Neck -- Cancer -- Prevention. --- Head --- Neck --- Neoplasms by Site --- Head and Neck Neoplasms --- Neoplasms --- Diseases --- Medicine --- Oncology --- Health & Biological Sciences --- Epidemiology --- Cancer --- Pathogenesis --- Prevention --- Epidemiology. --- Pathogenesis. --- Prevention. --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Figure drawing --- Skull --- Oncology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Physiological effect
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More than 180 participants and experts from 31 countries met for the fifth time in 10 years in St. Gallen, Switzerland for a 3-day conference to discuss important current issues of clinical cancer prevention. The meeting was again organized and co-sponsored by St. Gallen Oncology Conferences (SONK). While SONK has been extremely successful in organizing large international c- gresses on “Primary Therapy of Early Breast Cancer” as well as “Supportive Care in Cancer” for more than 20 years, the idea of promoting interdisciplinary, clinically oriented meetings on cancer prevention is a more recent and not yet generally accepted and w- comed concept in modern oncology. Since today’s medical expenses are soaring and me- cal research budgets are stagnating or even being cut, neither politicians nor industry is willing to risk an additional unpredictable channel of expenses, such as that demanded by clinical cancer prevention efforts! In Switzerland—and we fear in many other parts of the globe—some 97%–98% or even a greater percentage of health budgets is spent for curative and palliative/rehabilitative m- icine. Since a meager 2%–3% of national health budgets is for preventive medicine, even less than that proportion is specifically allocated for cancer prevention. When the money for “curing and caring” for the diseased populace runs short, there is likely not much left for partly controversial disease prevention in the (still) healthy part of the population.
Cancer -- Genetic aspects -- Congresses. --- Cancer -- Genetic aspects. --- Cancer -- Prevention -- Congresses. --- Cancer -- Prevention. --- Chemoprevention -- Congresses. --- Neoplasms -- genetics -- Congresses. --- Cancer --- Biology --- Diseases --- Drug Therapy --- Publication Formats --- Therapeutics --- Biological Science Disciplines --- Publication Characteristics --- Natural Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Genetics --- Congresses --- Chemoprevention --- Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Prevention --- Genetic aspects --- Medicine. --- Cancer research. --- Oncology. --- Medicine & Public Health. --- Cancer Research. --- Tumors --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians
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Oncology. Neoplasms --- Neoplasms --- Cancer --- Tumors --- Tumeurs --- Periodicals. --- Périodiques --- Neoplasms. --- Cancer. --- Tumors. --- Benign Neoplasms --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Benign Neoplasm --- Cancers --- Neoplasm, Benign --- Tumor --- Medical Oncology --- Periodicals --- Health Sciences --- Clinical Medicine --- Oncology --- Malignancy --- Malignancies --- Neoplasias --- Health Sciences. --- Oncology. --- Tumours --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- cancer --- translational oncology --- clinical oncology --- cancer epidemiology --- cancer prevention --- Malignant Neoplasms --- Malignant Neoplasm --- Neoplasm, Malignant --- Neoplasms, Malignant --- Pathology --- Cysts (Pathology)
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This book reviews the recent progress made in the prevention, diagnosis, and treatment of esophageal cancer. Epidemiology, molecular biology, pathology, staging, and prognosis are first discussed. The radiologic assessment of esophageal cancer and the role of endoscopy in diagnosis, staging, and management are then described. The principles of surgical resection, radiation therapy, and systemic chemotherapy for esophageal cancer are explained, and particular attention is paid to the multidisciplinary management of early-stage cervical, thoracic, distal, and junctional tumors. Up-to-date information is also provided on the treatment of metastatic and recurrent disease and on approaches that may affect future care, such as chemoprevention. Esophageal cancer remains one of the least studied cancers although it accounts for more than 400,000 deaths across the globe each year. The majority of esophageal cancers worldwide are squamous cell carcinomas, yet in the past few decades major epidemiologic changes have occurred affecting the incidence of adenocarcinomas in Western countries. Despite the advances in surgical and non-surgical therapies, overall survival has not changed significantly. It is hoped that Esophageal Cancer: Prevention, Diagnosis and Therapy will assist specialists from a variety of disciplines, including surgery, radiation therapy, gastroenterology, and medical oncology, in delivering optimal, up-to-date care to the benefit of patients.
Medicine & Public Health. --- Oncology. --- Pathology. --- Radiotherapy. --- Surgery. --- Medicine. --- Médecine --- Radiothérapie --- Cancérologie --- Pathologie --- Chirurgie --- Esophagus -- Cancer -- Diagnosis. --- Esophagus -- Cancer -- Prevention. --- Esophagus -- Cancer -- Treatment. --- Esophagus -- Cancer. --- Oncology --- Medicine --- Health & Biological Sciences --- Esophagus --- Cancer. --- Cancer --- Diagnosis. --- Treatment. --- Prevention. --- Oesophagus --- Alimentary canal --- Throat --- Oncology . --- Surgery, Primitive --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Tumors --- Radiological services
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The theory of a stem-cell origin of cancer is neither ground breaking nor earth shattering. Many prominent investigators have established the foundation for this concept and performed the vital experiments to support its validity and merit. The purpose of this book is to illustrate how this theory may completely transform our current views and perspectives about cancer. It is anticipated that the variety of ramifications of a stem-cell origin of cancers will be embraced by the medical research community to bring new treatment modalities to the cancer patient. "The stem-cell theory of cancer has significant biologic and clinical consequences. Though components remain open to debate the fundamental observations are grounded in scientific experimentation. This text explains the conceptual aspects of cancer stem cells with an emphasis on the implications for our patients." - Steven T. Rosen, M.D. Series Editor .
Cancer -- Epidemiology. --- Cancer -- Etiology. --- Cancer -- Prevention. --- Cancer --- Stem cells --- Neoplasms --- Diseases --- Oncology --- Medicine --- Health & Biological Sciences --- Etiology --- Stem cells. --- Etiology. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Medicine. --- Cancer research. --- Human genetics. --- Oncology. --- Medicine & Public Health. --- Cancer Research. --- Human Genetics. --- Cells
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Cancer screening is a prominent strategy in cancer control in the United States, yet the ability to correctly interpret cancer screening data eludes many researchers, clinicians, and policy makers. This open access primer rectifies that situation by teaching readers, in simple language and with straightforward examples, why and how the population-level cancer burden changes when screening is implemented, and how we assess whether that change is of benefit. This book provides an in-depth look at the many aspects of cancer screening and its assessment, including screening phenomena, performance measures, population-level outcomes, research designs, and other important and timely topics. Concise, accessible, and focused, Assessment of Cancer Screening: A Primer is best suited to those with education or experience in clinical research or public health in the United States - no previous knowledge of cancer screening assessment is necessary. This is the first text dedicated to cancer screening theory and methodology to be published in 20 years.
Early Detection of Cancer. --- Cancer Screening --- Cancer Screening Tests --- Early Diagnosis of Cancer --- Cancer Early Detection --- Cancer Early Diagnosis --- Cancer Screening Test --- Screening Test, Cancer --- Screening Tests, Cancer --- Screening, Cancer --- Test, Cancer Screening --- Tests, Cancer Screening --- Cancer Prevention --- Cancer Statistics --- Cancer Performance Measures --- Cancer Population Measures --- Cancer Screening Process --- Open Access --- Càncer --- Diagnòstic --- Cribratge
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This book collects some recent scientific data on the role of polyphenols in various pathological contexts, ranging from viral infection to metabolic or chronic disorders such as diabetes and renal fibrosis. The included studies showed both in vitro and in vivo evidence concerning positive effects of polyphenols in inflammation, apoptosis, and oxidative stress. The investigated molecules include: verbascoside from Olea europea, curcumin from Curcuma longa, phenolic acids from Antirhea borbonica, and phlorotannins from marine algae. Finally, the main flavonoids present in the human diet and their anti-inflammatory and anti-cancer roles were also discussed. The scientific data confirm the importance of the plant kingdom, both marine and terrestrial, in the search for new compounds with potential benefits for humans.
flavonoids --- inflammation --- p53 --- cancer prevention --- Nrf2 pathway --- anti-oxidant --- verbascoside --- polyphenols --- insulin-producing cells --- diabetes --- UPR --- oxidative stress --- ER-stress --- PERK --- anti-inflammatory --- mitochondria --- antioxidants --- marine algae --- anti-viral activity --- mechanism of action --- Antirhea borbonica --- kidney fibrosis --- caffeic acid --- antioxidant enzymes --- DESI-imaging --- curcumin --- glioblastoma cells --- radiation --- n/a
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