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Advances in Combinatorial Chemistry & High Throughput Screening, is an e-book series comprising updated research articles previously published in the impact factor journal, Combinatorial Chemistry & High Throughput Screening (CCHTS). A wide range of topics are covered by these articles including chemical biology, high throughput screening, combinatorial chemistry, chemoinformatics, laboratory automation and compound management. This series is, therefore, a testament to CCHTS contributions in advancing drug discovery on full throttle. This eBook series opens up a new avenue for rapid access for
Combinatorial chemistry. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Synthesis
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Combinatorial chemistry. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Synthesis
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Modern Organofluorine Chemistry-Synthetic Aspects - The volume focuses on recent advances in organofluorine chemistry directed towards selective fluorine introduction into various target molecules, employing both traditional and contemporary, electrophilic and nucleophilic, fluorinating agents. It brings together sixteen chapters written by leading experts and active researchers in the field. It is an excellent source of information for synthetic chemists interested in selective fluorination methods and fluorinated building blocks. Advances in Organic Synthesis is a book series devoted to publ
Organic compounds --- Combinatorial chemistry. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Pharmaceutical chemistry --- Biochips --- Chemistry, Organic --- Chemistry, Synthetic organic --- Organic synthesis (Chemistry) --- Synthetic organic chemistry --- Synthesis. --- Synthesis
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This book offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages.
High throughput screening (Drug development) --- Combinatorial chemistry. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- High throughput testing (Drug development) --- HRS (Drug development) --- Drug development --- Synthesis
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The words ""Combinatorial Chemistry"" have different meanings to different people, ranging from split and mix strategies to parallel synthesis using robots, and embracing the whole range of preparative chemistry from organic molecules, to catalyst ligands, and even inorganic solids. All of these activities have in common an attempt to expand the diversity of structure available to the chemist as well as the access to this diversity, permitting the discovery of new and valuable biological acid material properties.
Combinatorial chemistry --- Combinatorial chemistry. --- Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Synthesis
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A WWW only publication which contains articles on combinatorial chemistry accepted for publication in: Tetrahedron, Tetrahedron Letters, Tetrahedron:Asymmetry, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, CarbohydrateResearch, and other relevant Elsevier Science journals. It also features specially commissioned topical reports, as well as abstracts of articles from other publications. Articles are designated with page number and are published continuously in annual volumes.
chemie --- Descriptive organic chemistry --- Combinatorial chemistry --- Chimie combinatoire --- Periodicals. --- Périodiques --- Combinatorial chemistry. --- Biotechnologie. --- Zeitschrift. --- Online-Publikation. --- Kombinatorische Synthese. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Biotechnologie --- Kombinatorische Synthese --- Online-Ressource --- Zeitschrift --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Periodikum --- Zeitschriften --- Presse --- Fortlaufendes Sammelwerk --- Netzpublikation --- Online-Publikation --- Computerdatei im Fernzugriff --- Online-Dokument --- On-line-Dokument --- On-line-Publikation --- Elektronische Publikation --- Kombinatorische Chemie --- Kombinatorische Biologie --- Biokombinatorische Synthese --- Organische Synthese --- Molekülbibliothek --- Technische Biochemie --- Technische Biologie --- Biotechnik --- Biotech --- Industrielle Mikrobiologie --- Synthesis --- Molekülbibliothek
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In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cove
Bioinformatics. --- Biometry. --- Genetics. --- Genomics. --- Bioinformatics --- Genomics --- Computing Methodologies --- Databases, Factual --- Biology --- Databases as Topic --- Biological Science Disciplines --- Information Science --- Information Storage and Retrieval --- Information Systems --- Natural Science Disciplines --- Disciplines and Occupations --- Medical Informatics Applications --- Medical Informatics --- Databases, Genetic --- Computational Biology --- Software --- Health & Biological Sciences --- Genetics --- Biology - General --- Chemogenomics. --- Proteomics. --- Pharmacogenetics. --- Biochemical genetics. --- DNA microarrays. --- Combinatorial chemistry. --- Chemical genomics --- Genomes --- Biochemical genetics --- Chemicals --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- DNA biochips --- Microarrays, DNA --- Immobilized nucleic acids --- Chemical genetics --- Biochemistry --- Molecular genetics --- Pharmacology --- Molecular biology --- Proteins --- Effect of chemicals on --- Physiological effect --- Synthesis --- Genetic aspects
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High throughput sequencing (HTS) technologies have conquered the genomics and epigenomics worlds. The applications of HTS methods are wide, and can be used to sequence everything from whole or partial genomes, transcriptomes, non-coding RNAs, ribosome profiling, to single-cell sequencing. Having such diversity of alternatives, there is a demand for information by research scientists without experience in HTS that need to choose the most suitable methodology or combination of platforms and to define their experimental designs to achieve their specific objectives. Field Guidelines for Genetic Experimental Designs in High-Throughput Sequencing aims to collect in a single volume all aspects that should be taken into account when HTS technologies are being incorporated into a research project and the reasons behind them. Moreover, examples of several successful strategies will be analyzed to make the point of the crucial features. This book will be of use to all scientist that are unfamiliar with HTS and want to incorporate such technologies to their research.
Medicine. --- Human genetics. --- Systems biology. --- Biostatistics. --- Biomedicine. --- Human Genetics. --- Systems Biology. --- Nucleotide sequence. --- Combinatorial chemistry. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Sequence, Nucleotide --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Nucleic acids --- Nucleotides --- Sequence alignment (Bioinformatics) --- Synthesis --- Analysis --- Biological models. --- Statistical methods. --- Models, Biological --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Biological statistics --- Biology --- Biometrics (Biology) --- Biostatistics --- Biomathematics --- Statistics --- Computational biology --- Bioinformatics --- Biological systems --- Molecular biology --- Statistical methods
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Solid-phase synthesis. --- Combinatorial chemistry. --- Chimie combinatoire --- Solid-phase synthesis --- Combinatorial chemistry --- Polymers --- Combinatorial Chemistry Techniques --- Biomedical and Dental Materials --- Investigative Techniques --- Technology, Pharmaceutical --- Macromolecular Substances --- Chemicals and Drugs --- Manufactured Materials --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Technology, Industry, and Agriculture --- Technology, Industry, Agriculture --- Organic Chemistry --- Biochemistry --- Chemistry - General --- Chemistry --- Physical Sciences & Mathematics --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Chemistry. --- Organic chemistry. --- Organometallic chemistry. --- Medicinal chemistry. --- Biochemistry. --- Organic Chemistry. --- Biochemistry, general. --- Organometallic Chemistry. --- Medicinal Chemistry. --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Synthesis --- Chemistry, Organic. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Organic chemistry --- Composition --- Organometallic chemistry . --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry, Organometallic --- Metallo-organic chemistry --- Chemistry, Organic
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This volume of Pharmacochemistry Library comprises the text of invited lectures presented at the 11th Noordwijkerhout-Camerino Symposium Trends in Drug Research, held in Noordwijkerhout, The Netherlands, from 11-15 May 1997. In the programme attention has been given to the generation of new biological target systems and the generation of new lead molecules, with presentations on e.g. combinatorial chemistry, compound libraries, database search, high throughput screening and molecular biology. Other topics discussed were the perspectives for new medicines for the gastro-intes
Pharmacology, Experimental --- Pharmaceutical chemistry --- Combinatorial chemistry --- Drug development --- Congresses --- Drug Design --- Chemistry, Pharmaceutical --- Pharmacology --- Pharmacologies --- Pharmaceutical Preparations --- Chemistry, Pharmaceutic --- Pharmaceutic Chemistry --- Pharmaceutical Chemistry --- Medicinal Chemistry --- Chemistry, Medicinal --- Drug Modeling --- Design, Drug --- Designs, Drug --- Drug Designs --- Drug Modelings --- Modeling, Drug --- Modelings, Drug --- pharmacology --- Conferences - Meetings --- Experimental pharmacology --- Therapeutics, Experimental --- Development of drugs --- Drugs --- New drug development --- Pharmacy --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Biochips --- Development --- Synthesis --- Pharmacology. --- Computer-Aided Drug Design --- Computerized Drug Design --- Pharmaceutical Design --- Computer Aided Drug Design --- Computer-Aided Drug Designs --- Computerized Drug Designs --- Design, Computer-Aided Drug --- Design, Computerized Drug --- Design, Pharmaceutical --- Designs, Computer-Aided Drug --- Designs, Computerized Drug --- Designs, Pharmaceutical --- Drug Design, Computer-Aided --- Drug Design, Computerized --- Drug Designs, Computer-Aided --- Drug Designs, Computerized --- Pharmaceutical Designs --- Pharmacology, Experimental - Congresses --- Pharmaceutical chemistry - Congresses --- Combinatorial chemistry - Congresses --- Drug development - Congresses
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