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Book
Modern applications of cycloaddition chemistry
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ISBN: 0128152745 0128152737 9780128152744 9780128152737 Year: 2019 Publisher: Amsterdam, Netherlands : Elsevier,

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Book
Pericyclic reactions : a mechanistic and problem-solving approach
Authors: --- ---
ISBN: 0128036699 0128036400 9780128036693 9780128036402 Year: 2016 Publisher: London, UK : Elsevier Science,

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Pericyclic Reactions: A Mechanistic and Problem-Solving Approach provides complete and systematic coverage of pericyclic reactions for researchers and graduate students in organic chemistry and pharmacy programs. Drawing from their cumulative years of teaching in the area, the authors use a clear, problem-solving approach, supplemented with colorful figures and illustrative examples. Written in an accessible and engaging manner, this book covers electrocyclic reactions, sigmatropic reactions, cycloaddition reactions, 1,3-dipolar reactions, group transfer, and ene reactions. It offers an in


Book
Topological polymer chemistry : progress of cyclic polymers in syntheses, properties and functions
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ISBN: 1299281265 9814401285 9789814401289 9814401277 9789814401272 9781299281264 Year: 2013 Publisher: Singapore ; Hackensack, NJ : World Scientific,

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There are examples aplenty in the macroscopic world that demonstrate the form of objects directing their functions and properties. On the other hand, the fabrication of extremely small objects having precisely defined structures has only recently become an attractive challenge, which is now opening the door to nanoscience and nanotechnology.In the field of synthetic polymer chemistry, a number of critical breakthroughs have been achieved during the first decade of this century to produce an important class of polymers having a variety of cyclic and multicyclic topologies. These developments no

Cycloaddition Reactions in Organic Synthesis
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ISBN: 0080347134 0080347126 9780080347127 9780080347134 Year: 1990 Volume: 8 Publisher: Elmsford, NY : Pergamon,


Book
Synthesis of Heterocycles via Cycloadditions II
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ISBN: 9783540783688 9783540783725 3540783687 3540783725 3540783717 3540783733 Year: 2008 Volume: 12-13 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,


Book
Cycloadditions in Bioorthogonal Chemistry
Authors: ---
ISBN: 3319296841 3319296868 Year: 2016 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.


Book
Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds
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ISBN: 4431540423 9786613452665 1283452669 4431540431 Year: 2012 Publisher: Tokyo : Springer Japan : Imprint: Springer,

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The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure.


Book
Stereoselective Heterocycle Synthesis via Alkene Difunctionalization : Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation
Author:
ISBN: 3319775073 3319775065 Year: 2018 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book investigates the use of palladium modified by bulky ligands as catalysts for new chemical transformations that rapidly assemble several classes of complex heterocyles. It documents the development of new chemical reactions involving carbon–carbon (C‒C) and carbon–halogen (C‒X) bond formation in the context of alkene difunctionalization and dearomatization reactions. Due to the ubiquity of heterocycles in bioactive natural products and life-improving pharmaceutical treatments, a long-term goal for synthetic organic chemists has been to develop novel and creative heterocycle syntheses that illicit a high degree of product diversity and are characterized by mild reaction conditions and limited waste production. A considerable fraction of leading pharmaceutical drugs contain at least one heterocycle within their chemical structure, and their prevalence in these technologies is strong evidence that the fundamental curiosities of organic chemistry lead to real-world solutions for the health and wellness of the global population.

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