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The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
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Plants possess the ability to biosynthesize a large variety of steroids, but it was not until 1979 that a hormonal function was demonstrated in plants. Today, about 40 structurally and functionally related steroids, known as brassinosteroids, have been isolated from natural sources. Brassinosteroids demonstrate various kinds of regulatory activities in the growth and development of plants. This book is based on a 1990 Russian monograph, but includes all important subsequent literature and developments, including unpublished data from the authors' laboratories.Key Features* BRASSINO
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Steroid hormones. --- Hormonal steroids --- Hormones --- Steroids
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Steroids. --- Steroid drugs. --- Steroids --- chemistry --- theraputic use
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Steroids. --- Steroids --- Sterides --- Sterids --- Cyclopentaphenanthrene --- Lipids --- Health aspects.
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Steroids --- Steroid hormones --- Steroids. --- Stéroïdes --- Hormones stéroïdes --- Steroid hormones. --- Sterides --- Sterids --- Hormonal steroids --- Catatoxic Steroids --- Steroids, Catatoxic --- Cyclopentaphenanthrene --- Lipids --- Hormones --- Steroid --- Stéroïdes.
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Steroids: The basic science and clinical aspects covers the modern understanding and clinical use of steroids. The history of steroids is richly immersed and runs long and deep. The modern history of steroids started in the early 20th century, but its use has been traced back to ancient Greece. We start by describing the basic science of steroids. We then describe different clinical situations where steroids play an important role. We hope that this book will contribute further to the literature available about steroids and enables the reader to further understand this interesting and rapidly evolving science.
Steroids. --- Sterides --- Sterids --- Cyclopentaphenanthrene --- Lipids --- Reproductive medicine
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This book explains the basic science of steroids and is targeted towards professionals engaged in health services. It should be noted that medical science evolves rapidly and some information like the understanding of steroids and their therapeutic use may change with new concepts quickly. Steroids are either naturally occurring or synthetic fat-soluble organic compounds. They are found in plants, animals, and fungi. They mediate a very diverse set of biological responses. The most widespread steroid in the body is cholesterol, an essential component of cell membranes, and the starting point for the synthesis of other steroids. Since the science of steroids has an enormous scope, we decided to put the clinical aspects of steroids in a different book titled "Steroids-Clinical Aspects". The two books complete each other. We hope that the reader will gain valuable information from both books and enrich their knowledge about this fascinating topic.
Steroids. --- Sterides --- Sterids --- Cyclopentaphenanthrene --- Lipids --- Endocrinology
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