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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

histone deacetylation --- CpG methylation --- cytocrin --- epigenetic factors --- Epigenetic traits --- Pregnancy --- Sugar metabolism --- eye epigenetics --- in vitro fertilization

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The field of In Vitro Fertilization is a relatively new field in medicine, constantly on the move. This field is an exquisite example of the vast power in the complementary use of basic research with clinical practice and opened a new route of great basic and clinical research possibilities. The knowledge base that allowed the accomplishment of the idea of in vitro fertilization and embryo transfer has much developed since. The vast body of research pertaining to this field allowed deepening our understanding in the processes related to reproduction. In this book on in vitro fertilization we present new and interesting updated information in various aspects of this field. This work is a result of collaborative work of an international group of professionals dedicated to contribute to the advancement of our knowledge.

Fertilization in vitro. --- Fertilization in vitro, Human. --- Babies, Test tube --- Human fertilization in vitro --- Human in vitro fertilization --- Test tube babies --- Conception --- Human reproductive technology --- Ectogenesis, Preimplantational --- Fertilization, In vitro --- Fertilization, Laboratory --- Fertilization, Test tube --- In vitro fertilization --- IVF (Reproduction) --- Laboratory fertilization --- Preimplantational ectogenesis --- Test tube fertilization --- Genetic engineering --- Reproductive technology --- Urology & urogenital medicine

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Even 30 years after the birth of the first "artificially produced baby Louise Brown in 1978, the desire for a child remains unfulfilled for many couples. Their hopes are to modern techniques of assisted reproduction. Reproductive medicine has since made enormous progress and opens up new opportunities. With these opportunities, however, are also linked new challenges, their moral and legal implications are considerable. Auch 30 Jahre nach der Geburt des ersten „Retortenbabys“ Louise Brown im Jahr 1978 bleibt für viele Paare der Wunsch nach einem eigenen Kind unerfüllt, und ihre Hoffnungen richten sich auf moderne Techniken assistierter Reproduktion. Die Reproduktionsmedizin hat seitdem immense Fortschritte gemacht und neue Chancen eröffnet. Mit diesen Chancen ist indessen zugleich eine Fülle neuer Herausforderungen verbunden, deren moralische und rechtliche Implikationen erheblich sind. Der vorliegende Band vereint Beiträge zweier Tagungen, die im Jahr 2007 vom »Forum für Ethik in der Medizin Frankfurt am Main e.V.« gemeinsam mit der »Arbeitsgruppe Reproduktionsmedizin und Embryonenschutz in der Akademie für Ethik in der Medizin« sowie vom »Zentrum für Medizinrecht« der Universität Göttingen veranstaltet wurden und welche die aktuelle Debatte um die Reproduktionsmedizin und ihre Möglichkeiten aufgreifen. Sie wenden sich den Errungenschaften und Problemen assistierter Fortpflanzung im Allgemeinen zu, widmen jedoch ihr Augenmerk speziell donogenen Techniken (Eizellspende, Samenspende, Embryospende) sowie dem Kinderwunsch in besonderen Situationen (etwa körperliche Behinderung, letale Erkrankung eines Partners, gleichgeschlechtliche Lebensgemeinschaften).

Human reproduction --- Fertilization in vitro, Human --- Reproductive Techniques --- Therapeutics --- Investigative Techniques --- Reproductive Techniques, Assisted --- Law and legislation. --- Brown, Louise, --- retort --- child --- birth --- parents --- in vitro fertilization --- medicine --- Deutschland --- Ethik --- In-vitro-Fertilisation --- Künstliche Befruchtung --- Reproduktionsmedizin --- Unfruchtbarkeit

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An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differences between natural cycle IVF and stimulated IVF are presented in part II, including the standard ovarian stimulation protocols and their outcomes and the etiology, prevention and management of ovarian hyperstimulation syndrome (OHSS). Minimal and mild stimulation for IVF is discussed in part III, including mild stimulation protocols for oncofertility patients and the new minimally invasive INVO procedure. In vitro maturation as a clinical treatment is the subject of part IV, discussing the methodology of immature oocyte retrieval as well as other laboratory aspects and congenital and obstetrical outcomes of babies born from IVM. Combining expertise from thought leaders around the world, Development of In Vitro Maturation for Human Oocytes will be a go-to resource for infertility researchers and practitioners and reproductive endocrinologists working with infertile couples looking for safer and more cost-effective options for treatment.

Medicine. --- Endocrinology. --- Reproductive medicine. --- Medicine & Public Health. --- Reproductive Medicine. --- Fertilization in vitro. --- Ectogenesis, Preimplantational --- Fertilization, In vitro --- Fertilization, Laboratory --- Fertilization, Test tube --- In vitro fertilization --- IVF (Reproduction) --- Laboratory fertilization --- Preimplantational ectogenesis --- Test tube fertilization --- Genetic engineering --- Reproductive technology --- Internal medicine --- Hormones --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Health aspects --- Endocrinology .

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Infertility --- Fertilization in vitro. --- Integrative medicine. --- Medical pluralism --- Medicine --- Alternative medicine --- Ectogenesis, Preimplantational --- Fertilization, In vitro --- Fertilization, Laboratory --- Fertilization, Test tube --- In vitro fertilization --- IVF (Reproduction) --- Laboratory fertilization --- Preimplantational ectogenesis --- Test tube fertilization --- Genetic engineering --- Reproductive technology --- Involuntary childlessness --- Sterility --- Sterility in humans --- Childlessness --- Generative organs --- Fertility, Human --- Sterilization (Birth control) --- Prevention. --- Diseases