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Viruses: From Understanding to Investigation provides students with a map for lifetime learning by presenting the definition and unique characteristics of viruses, including major topics, such as the virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions and methods to study viruses. In addition, the book assesses the connections between, and among, the aforementioned topics, providing an integrated approach and in-depth understanding of how viruses work.

Viruses.

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Respiratory syncytial virus (RSV) causes seasonal epidemics during the winter and wet seasons, particularly in young children. Although there is one drug available for prophylaxis, palivizumab, it is indicated for high-risk children only. Therefore a vaccine is urgently needed. This book provides an overview of RSV and discusses its incidence and presentation in different populations, including preterm infants and children with congenital heart disease. It also discusses future strategies for RSV prophylaxis and developments in and barriers to creating a viable vaccine.

Viruses.

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RNA Viruses: A Practical Approach is wide ranging in scope, from emerging technology such as reverse genetics and retrovirus vectors, to money saving tips - how to make your own silica particles for high efficiency RNA extraction and liposomes for cell transfection! Chapter one covers the fundamentals of investigating RNA virus genome structure at a molecular level. Chapters two and three describe techniques for mutagenesis of RNA genomes and analysis of transcription. Chapter four deals with RNA virus-encoded proteinases, an important aspect of the control of RNA virus gene expression. Chapter five considers retrovirus oncogenesis and chapter six analysis of RNA virus quasispecies. Chapter seven describes systems for investigation of in vitro replication of positive-stranded viruses and chapter eight the packaging of RNA virus genomes. In addition to the technical aspects of reverse genetics and retrovirus vectors, both of the final two chapters also consider ethical aspects of these new technologies.

RNA viruses. --- Riboviruses --- Viruses, RNA --- Viruses

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The practical need to partition the world of viruses into distinguishable, universally agreed upon entities is the ultimate justification for developing a virus classification system. Since 1971, the International Committee on Taxonomy of Viruses (ICTV) operating on behalf of the world community of virologists has taken on the task of developing a single, universal taxonomic scheme for all viruses infecting animals (vertebrate, invertebrates, and protozoa), plants (higher plants and algae), fungi, bacteria, and archaea. The current report builds on the accumulated taxonomic construction of

Viruses --- Virology

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"Harnessing the Power of Viruses explores the application of scientific knowledge about viruses and their "lives" to solve practical challenges and further advance molecular sciences, medicine, and agriculture. Virus-based tools and approaches in the fields of: (1) DNA manipulations in vitro and in vivo; (2) Protein expression and characterization; and (3) Virus-Host interactions as a platform for therapy and biocontrol are discussed. The book steers away from traditional views of viruses and technology, focusing instead on viral molecules and molecular processes that enable science to better understand life and offer means for addressing complex biological phenomena that positively influence everyday life. This publication is written at an intermediate level and is accessible to novices who are willing to acquire a basic level of understanding of key principles in molecular biology, as well as to advanced readers interested in expanding their biological knowledge to include practical applications of molecular tools derived from viruses."--Page 4 of cover.

Viruses. --- Virology.