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Glycomics. --- Glycobiology --- Genomics --- Molecular biology --- Carbohydrates --- Glicòmica --- Immunitat

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In the past decade, there has been an explosion of progress in understanding the roles of carbohydrates in biological systems. This explosive progress was made with the efforts in determining the roles of carbohydrates in immunology, neurobiology and many other disciplines, examining each unique system and employing new technology. This volume represents the second of three in the Methods in Enzymology series, including Glycobiology (vol. 415) and Glycomics (vol. 416), dedicated to disseminating information on methods in determining the biological roles of carbohydrates. These books are

Analysis. --- Carbohydrates. --- Chemistry. --- Etiology. --- Galectins. --- Glycolipids. --- Glycomics. --- Methods. --- Muscular Dystrophies. --- Physiology. --- Proteomics. --- Chemicals and Drugs --- Lipids --- Glycoconjugates --- Glycolipids --- Carbohydrates --- Glycobiology --- Genomics --- Molecular biology

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This book presents state of the art biophysical approaches to issues in glycobiology that have cutting-edge applications. Despite the importance of glycosylation, the complexity, heterogeneity, and flexibility of the glycans have inhibited their study. Each chapter in this book explains very recent significant advances in biophysical approaches through the use of techniques such as NMR spectroscopy, mass spectrometry, single-molecule imaging, X-ray crystallography, high-speed atomic force microscopy, and computational simulation and their integrative application. Concrete examples are provided of the value of these techniques in addressing key problems in the field. In addition, significant functional glycobiological issues are considered. For example, glycolipids can form dynamic clusters on cell membranes and provide platforms for molecules involved in cell recognition and subsequent signal transduction. The detailed delineation of these molecular systems is discussed, revealing their structural complexity and ability to assemble transiently. This timely book will be of value for graduate students and postdocs interested in frontier topics in glycoscience and also for senior bio-researchers in academic and industrial fields.

Glycomics. --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Glycobiology --- Genomics --- Molecular biology --- Carbohydrates --- Composition --- Biochemistry, general. --- Biological and Medical Physics, Biophysics.

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It is my great honor and pleasure to introduce this comprehensive book to readers who are interested in carbohydrates. This book contains 23 excellent chapters written by experts from the fields of chemistry, glycobiology, microbiology, immunology, botany, zoology, as well as biotechnology. According to the topics, methods and targets, the 23 chapters are further divided into five independent sections. In addition to the basic research, this book also offers much in the way of experiences, tools, and technologies for readers who are interested in different fields of Glycobiology. I believe that readers can obtain more than anticipated from this meaningful and useful book.

Carbohydrates. --- Glucides. --- Glycomics. --- Glycobiology --- Genomics --- Molecular biology --- Carbohydrates --- Glucosides --- Carbs (Carbohydrates) --- Biomolecules --- Organic compounds --- Glycomics --- Life Sciences --- Genetics and Molecular Biology --- Chemical Biology --- Biochemistry --- Bioorganic Chemistry

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In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers' own research efforts Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves. Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry.

Glycomics. --- Carbohydrates. --- Biochemistry --- Genomics --- Carbohydrate Metabolism --- Organic Chemistry Processes --- Carbohydrate Biochemistry --- Glycomics --- Glycosylation --- Metabolism --- Chemical Processes --- Organic Chemistry Phenomena --- Biochemical Processes --- Chemistry --- Genetics --- Computational Biology --- Chemical Phenomena --- Biology --- Metabolic Phenomena --- Biological Science Disciplines --- Biochemical Phenomena --- Natural Science Disciplines --- Phenomena and Processes --- Disciplines and Occupations --- Human Anatomy & Physiology --- Animal Biochemistry --- Health & Biological Sciences --- Glycobiology --- Carbs (Carbohydrates) --- Molecular biology --- Carbohydrates --- Biomolecules --- Organic compounds