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This is a book about the physical processes in reacting complex molecules, particularly biomolecules. In the past decade scientists from different fields such as medicine, biology, chemistry and physics have collected a huge amount of data about the structure, dynamics and functioning of biomolecules. Great progress has been achieved in exploring the structure of complex molecules. However, there is still a lack of understanding of the dynamics and functioning of biological macromolecules. In particular this refers to enzymes, which are the basic molecular machines working in living systems. This book contributes to the exploration of the physical mechanisms of these processes, focusing on critical aspects such as the role of nonlinear excitations and of stochastic effects. An extensive range of original results has been obtained in the last few years by the authors, and these results are presented together with a comprehensive survey of the state of the art in the field.

Physical biochemistry. --- Stochastic processes. --- Biomolecules --- Biological molecules --- Molecules --- Molecular biology --- Random processes --- Probabilities --- Biophysical chemistry --- Biochemistry --- Physical organic chemistry --- Reactivity. --- Structure. --- Differential geometry. Global analysis --- Stochastic processes --- Biomathematics. Biometry. Biostatistics

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Biological Thermodynamics provides an introduction to the study of energy transformations for students of the biological sciences. Don Haynie uses an informal writing style to introduce this core subject in a manner which will appeal to biology and biochemistry undergraduate students and be relevant to their studies. The emphasis is on understanding basic concepts and developing problem-solving skills throughout the text, but mathematical complexity is kept to a minimum. Each chapter comprises numerous examples taken from different areas of biochemistry, as well as extensive exercises to aid understanding. Topics covered include energy and its transformation, the First Law of Thermodynamics, the Second Law of Thermodynamics, Gibbs Free Energy, statistical thermodynamics, binding equilibria and reaction kinetics, concluding with a survey of the most exciting areas of biological thermodynamics today, particularly the origin of life on Earth.

Bioenergetics. --- Physical biochemistry. --- Thermodynamics. --- Energy balance (Biology) --- Energy budget (Biology) --- Energy dynamics (Ecology) --- Energy utilization (Biology) --- Biophysical chemistry --- Bioenergetics --- Physical biochemistry --- Thermodynamics --- 577.31 --- Biochemistry --- Energy budget (Geophysics) --- Physical organic chemistry --- Chemistry, Physical and theoretical --- Dynamics --- Mechanics --- Physics --- Heat --- Heat-engines --- Quantum theory --- 577.31 Thermodynamics and kinetics of biological processes. Oscillatory phenomena in biological systems --- Thermodynamics and kinetics of biological processes. Oscillatory phenomena in biological systems --- General biochemistry --- Biothermodynamics. --- Biochemical thermodynamics --- Biological thermodynamics --- Biophysics

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Physicochemistry --- General biochemistry --- General biophysics --- fysicochemie --- Physical biochemistry --- Molecular biology --- Technique --- Biochemistry --- Molecular Biology --- Biophysics --- Biochimie --- Biologie moléculaire --- Biophysique --- methods. --- Technique. --- Methods. --- Biochemie --- #WSCH:MODS --- 577.1 --- 577.2 --- 577.3 --- 577.3 Physical and physicochemical bases of life. Biophysics. Biophysical chemistry in general --- Physical and physicochemical bases of life. Biophysics. Biophysical chemistry in general --- 577.2 Molecular bases of life. Molecular biology --- Molecular bases of life. Molecular biology --- 577.1 Chemical bases of life. Biochemistry and bio-organic chemistry generally --- Chemical bases of life. Biochemistry and bio-organic chemistry generally --- Biophysical chemistry --- Physical organic chemistry --- Physical biochemistry - Technique --- Molecular biology - Technique

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Chemistry --- 577.3 --- 577.1 --- 541.64 --- 535.33 --- Physical and physicochemical bases of life. Biophysics. Biophysical chemistry in general --- Chemical bases of life. Biochemistry and bio-organic chemistry generally --- Macromolecular chemistry. Polymerization products. Polycondensation products. Polyaddition products --- Spectra in general. Emission spectra --- 535.33 Spectra in general. Emission spectra --- 541.64 Macromolecular chemistry. Polymerization products. Polycondensation products. Polyaddition products --- 577.1 Chemical bases of life. Biochemistry and bio-organic chemistry generally --- 577.3 Physical and physicochemical bases of life. Biophysics. Biophysical chemistry in general --- Physical biochemistry --- Biophysical chemistry --- Biochemistry --- Physical organic chemistry

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Cheminformatics --- Bioinformatics --- Drugs --- Structure-activity relationships (Biochemistry) --- QSAR (Biochemistry) --- Cheminformatics. --- Structuur-activiteit-relatie. --- Biochemical Phenomena. --- Structure-activity relationships --- Structure-activity relationships. --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Processes --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Biochemorphology --- Biomolecules --- Chemical structure-biological activity relationships --- Relationships, Structure-activity (Biochemistry) --- Quantitative structure-activity relationships (Biochemistry) --- Structure-activity relationship (Pharmacology) --- Chemical informatics --- Chemiinformatics --- Chemoinformatics --- Chemistry informatics --- Bio-informatics --- Biological informatics --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Computational Biology --- Computer-Aided Design --- Biochemical Phenomena --- CAD-CAM --- Computer-Aided Manufacturing --- Computer-Assisted Design --- Computer-Assisted Manufacturing --- Computer Aided Design --- Computer Aided Manufacturing --- Computer Assisted Design --- Computer Assisted Manufacturing --- Computer-Aided Designs --- Computer-Assisted Designs --- Design, Computer-Aided --- Design, Computer-Assisted --- Designs, Computer-Aided --- Designs, Computer-Assisted --- Manufacturing, Computer-Aided --- Manufacturing, Computer-Assisted --- Bio-Informatics --- Biology, Computational --- Computational Molecular Biology --- Molecular Biology, Computational --- Bio Informatics --- Bio-Informatic --- Bioinformatic --- Biologies, Computational Molecular --- Biology, Computational Molecular --- Computational Molecular Biologies --- Molecular Biologies, Computational --- Physical biochemistry --- Pharmaceutical chemistry --- Pharmacology --- Chemistry --- Information science --- Biology --- Computational biology --- Systems biology --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacy --- Molecular Biology --- Genomics --- Data processing --- Health Sciences --- Pharmacy and Pharmacology --- Computational Biology. --- Computer-Aided Design. --- Drug Design --- Computational Chemistry --- Pharmacy, Therapeutics, & Pharmacology --- Computational chemistry