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Bones --- Non-coding RNA. --- Diseases --- Genetic aspects. --- fRNA --- Functional RNA --- ncRNA --- nmRNA --- Non-messenger RNA --- Non-translated RNA --- Noncoding RNA --- Nontranslated RNA --- Small non-messenger RNA --- Small RNA --- snmRNA --- sRNA --- Untranslated RNA --- RNA --- Teixit ossi --- Ossos (Teixits) --- Teixits ossis --- Esquelet --- Teixit connectiu --- Calcificació --- Ossos --- Àcid ribonucleic --- ARN --- Àcids nucleics --- Micro RNAs

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This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding RNAs and cardiovascular diseases, 5) Potential biomarkers and therapeutic implications, 6) Future prospects. It is particularly useful for researchers and students in the field of non-coding RNA and cardiovascular biology, as well as for cardiologists, pharmacologists and physiologists.

Molecular biology. --- Human genetics. --- Cardiology. --- Molecular Medicine. --- Human Genetics. --- Heart --- Internal medicine --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Diseases --- Cardiovascular system. --- Circulatory system --- Vascular system --- Blood --- Circulation --- Malalties cardiovasculars --- RNA --- Àcid ribonucleic --- ARN --- Àcids nucleics --- Micro RNAs --- Malalties de l'aparell cardiovascular --- Malalties del sistema cardiovascular --- Malalties --- Hipotensió arterial --- Malalties coronàries --- Malalties del cor --- Trombosi --- Cardiologia

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Bioactive compounds. --- Biologically active compounds --- Compounds, Bioactive --- Compounds, Biologically active --- Compounds, Physiologically active --- Physiologically active compounds --- Chemicals --- Membranes (Biologia) --- Biotecnologia --- Biomolècules --- Molècules biològiques --- Molècules --- Àcids nucleics --- Biopolímers --- Metabòlits --- Proteïnes --- Biologia molecular --- Biologia --- Enginyeria --- Antropometria --- Biosíntesi --- Biotecnologia agrícola --- Biotecnologia alimentària --- Biotecnologia farmacèutica --- Biotecnologia marina --- Biotecnologia microbiana --- Enginyeria bioquímica --- Enginyeria sanitària --- Ergonomia --- Indústries biotecnològiques --- Microbiologia industrial --- Reproducció assistida --- Bioreactors --- Interfícies biològiques --- Protoplasma --- Liposomes --- Membrana mucosa --- Membranes cel·lulars --- Membranes lipídiques --- Periosti --- Peritoneu --- Proteïnes de membrana

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There has been an enormous increase in information relating to microRNA (miRNA) and its strategic role in numerous diseases. This book reviews the emerging role of microRNAs in cerebral ischemia, providing comprehensive details of the links between this small RNA molecule and ischemic stroke, the more prevalent of the two main types of stroke. The chapters address questions relating to microRNA’s function in various pathological features of stroke, like oxidative stress, excitotoxicity and cell death, as well as its role as a biomarker and diagnostic agent, and the current therapeutic interventions. Further, the book highlights the latest research on how miRNAs contribute to neuroregeneration following stroke, discussing the myriad computational tools and databases used in miRNA research, and decsribes how how miRNA modulates other cerebrovascular diseases. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.

Cerebral ischemia. --- Brain ischemia --- Cerebrovascular disease --- Ischemia --- Neurosciences. --- Human genetics. --- Immunology. --- Apoptosis. --- Oxidative stress. --- Human Genetics. --- Oxidative Stress. --- Oxidation-reduction reaction --- Stress (Physiology) --- Cell death --- Immunobiology --- Life sciences --- Serology --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Malalties cerebrovasculars --- RNA --- Expressió gènica --- Expressió dels gens --- Expressió genètica --- Expressivitat genètica --- Expressivitat gènica --- Ressenya genètica --- Regulació genètica --- Vectors genètics --- Àcid ribonucleic --- ARN --- Àcids nucleics --- Micro RNAs --- Accidents cerebrovasculars --- Accidents vasculars cerebrals --- Apoplexia --- AVC --- Ictus apoplèctic --- Insult apoplèctic --- Malalties vasculars cerebrals --- Patologia vascular cerebral --- Síndrome cerebrovascular --- Trastorns cerebrovasculars --- Malalties cerebrals --- Malalties vasculars --- Embòlia i trombosi cerebral --- Infart cerebral --- Isquèmia cerebral --- Paràlisi

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The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting on the mRNAs, leading to a properly folded complex. This book shows how new technologies have led to a better understanding of these processes and their connected diseases. The book is written for scientists in fundamental and applied biomedical research working on different aspects of gene regulation. It is also targeted to an audience that is not implicated in these fields directly, but wants to gain a better understanding of mRNA biology.

Messenger RNA. --- Informational RNA --- Messenger ribonucleic acid --- mRNA --- Protein transcript --- Protein transcripts --- Template RNA --- RNA --- Molecular biology. --- Gene expression. --- Proteins . --- Neurosciences. --- Posttranslational modification. --- Molecular Medicine. --- Gene Expression. --- Protein-Ligand Interactions. --- Posttranslational Modification. --- Co-translational modification --- Cotranslational modification --- Modification, Post-translational --- Post-translation protein modification --- Post-translational protein modification --- Posttranslation protein modification --- Posttranslational modification --- Posttranslational protein modification --- Genetic translation --- Proteins --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Genes --- Genetic regulation --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Synthesis --- Expression --- Àcid ribonucleic --- ARN --- Àcids nucleics --- Micro RNAs --- Medicine—Research. --- Biology—Research. --- Molecular genetics. --- Proteins. --- Post-translational modification. --- Biomedical Research. --- Molecular Genetics. --- Protein Biochemistry. --- Neuroscience. --- Post-translational Modifications. --- Genetics --- Molecular biology