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"Antimicrobial resistance has existed in nature long before the discovery of antibiotics itself. The mechanisms of resistance are prevalent among the bacterial population. Over a period and facilitated by indiscriminate usage of antibiotics, these mechanisms are transferred from one type of bacteria to other, including the pathogenic ones. In addition, the rate of discovery of novel antimicrobials is much slower than the rate of evolution of antimicrobial resistance. Therefore, there is a need for alternative strategies to control antimicrobial resistance to save lives. In this book, the novel strategies to combat antimicrobial resistance are described, emphasizing collaborative measures of control. We describe the concerted efforts undertaken by global communities to combat antimicrobial resistance in detail. The most efficient strategy could be a behavioral change towards indiscriminate consumption, usage, and prescription of antibiotics"--
Drug resistance in microorganisms. --- Drug Resistance, Microbial. --- Antimicrobial Stewardship. --- Anti-Bacterial Agents --- Résistance microbienne aux médicaments. --- Résistance aux antibiotiques --- Gestion responsable des antimicrobiens. --- Antibactériens. --- therapeutic use. --- usage thérapeutique.
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healthcare-associated infections (hcais) --- infection prevention --- public health --- outbreaks --- antimicrobial stewardship --- decontamination --- Infection --- Infection Control. --- Cross Infection --- Prevention --- Prevention. --- prevention & control. --- Control, Infection --- Infections --- Communicable Disease Control --- Infectious diseases --- Diseases --- Medical microbiology --- prevention & control --- Causes and theories of causation
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Antimicrobial Stewardship --- Anti-Bacterial Agents --- Drug Resistance, Microbial. --- Inappropriate Prescribing --- Antibiotiques --- Résistance aux antibiotiques --- administration & dosage. --- prevention & control. --- Prescription. --- Modes d'administration. --- Modes d'administration --- Résistance aux antibiotiques
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This book contains a suite of original articles, case reports, and review articles on various aspects of travel medicine ranging from refugee and immigrant health to mass gathering medicine. It contains articles on infectious and environmental hazards of travel.
Medicine --- Burkholderia pseudomallei --- melioidosis --- ceftazidime --- resistance --- persistent bacteremia --- histoplasmosis --- travel --- outbreak --- Guatemala --- Hajj --- meningococcal disease --- vaccine uptake --- pre-travel health advice --- Saudi Arabia --- mass gathering --- survey --- health care workers --- knowledge --- attitudes --- perceptions --- antimicrobial resistance --- antimicrobial stewardship --- upper respiratory tract infection --- guideline --- pediatric eye problem --- eye care --- infant --- Rohingya refugee --- antimicrobial resistance (AMR) --- antimicrobial resistant bacteria (ARB) --- antimicrobial resistant genes (ARG) --- wastewater --- Hajj and Kumbh Mela --- cervical cancer --- human papillomavirus --- HPV vaccine --- attitudes and perceptions --- Bangladesh --- health literacy --- health status --- Myanmar --- Rakhine --- refugee --- Rohingya --- COVID-19 --- hand hygiene --- infection prevention and control --- infectious disease --- anticoagulant --- antiplatelet --- antithrombotic therapy --- SARS-CoV-2 --- thrombosis --- disseminated intravascular coagulation --- n/a
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This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.
Medicine --- internal medicine --- intensive care --- emergency department --- organ dysfunction --- immunomodulation --- micronutrients --- antimicrobial stewardship --- shock septic --- antioxidant therapy --- oxidative stress --- multiple organ failure --- procalcitonin --- qSOFA --- sepsis --- fever --- procalcitonin kinetics --- prognostication --- sepsis biomarkers --- vitamin D --- vitamin C --- zinc --- thiamine --- nutrition --- critically ill patients --- infections --- mitochondria --- shock --- multidrug-resistant bacteria --- Klebsiella NDM --- ceftazidime-avibactam --- septic shock --- infection --- extracorporeal immune modulation --- blood purification --- renal replacement therapy --- afebrile patients --- neutropenic enterocolitis --- chemotherapy-induced damage --- antifungal stewardship --- Candida bloodstream infection --- echinocandin --- Presepsin --- critical care --- ICU --- neutrophil-to-lymphocyte --- platelet-to-lymphocyte --- C-reactive protein --- MRproAdrenomedullin --- systemic inflammatory response syndrome --- sequential organ failure assessment --- quick-sequential organ failure assessment --- proadrenomedullin --- MR-proADM --- n/a
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Drug resistance in microorganisms --- Antibiotics --- Drug Resistance, Microbial. --- Anti-Infective Agents. --- Drug resistance in microorganisms. --- Antibiotics. --- Anti-infective agents --- Microbial metabolites --- Allelopathic agents --- Antibiosis --- Pharmaceutical microbiology --- Phytoncides --- Antibiotic resistance in microorganisms --- Antibiotics resistance in microorganisms --- Bacterial resistance to antibiotics --- Drug resistance in micro-organisms --- Microbial drug resistance --- Resistance to drugs in microorganisms --- Microorganisms --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Microbicides --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agents --- Anti Microbial Agents --- Infections --- Parasites --- Antimicrobial Drug Resistance --- Antibiotic Resistance --- Antibiotic Resistance, Microbial --- Antimicrobial Drug Resistances --- Drug Resistances, Microbial --- Resistance, Antibiotic --- Microbial Sensitivity Tests --- Effect of drugs on --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Anti Infective Agent --- Anti Microbial Agent --- antimicrobial resistance --- drug therapy --- antimicrobial stewardship --- infectious diseases
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Bacterial resistance to known and currently used antibiotics represents a growing issue worldwide. It poses a major problem in the treatment of infectious diseases in general and hospital-acquired infections in particular. This is in part due to the overuse and misuse of antibiotics in past decades, which led to the selection of highly resistant bacteria and even so-called superbugs – multidrug-resistant (MDR) bacteria. Nosocomial infections, particularly, are often caused by MDR bacterial pathogens and the treatment of such infections is very complicated and extensive, often leading to various side effects, including adverse effects on the natural human microbiome. At the same time, the development of novel antibiotics is lagging with very few new ones in the pipeline. Finding viable alternatives to treat such infections may help to overcome these therapeutic issues. This publication brings novel developments in the field of bacterial resistance, mainly in the hospital settings, adequate antibiotic therapy, and identification of compounds useful to battle this growing issue.
Medicine --- Epidemiology & medical statistics --- VRE --- GIT --- hemato-oncological patients --- clonality --- antibiotic stewardship --- resistance --- consumption of antibiotics --- clonal spread --- Enterococcus faecium --- Enterococcus faecalis --- linezolid resistance --- 23S rRNA --- optrA --- carbapenem-resistant Klebsiella pneumoniae --- carbapenem-resistant Acinetobacter baumannii --- N-acetylcysteine --- septic shock --- critically ill patients --- newborn --- infection --- bacteria --- antibiotic therapy --- hops --- C. difficile --- rat model --- Staphylococcus aureus --- MRSA --- spa typing --- MLST --- SCCmec typing --- clonal analysis --- epidemiology --- cancer patients --- duration of treatment --- colistin --- propensity score analysis --- multidrug-resistant Acinetobacter baumannii --- urinary tract infections --- UTIs --- MDR --- Escherichia coli --- Klebsiella --- uropathogens --- AMR --- antibiotic resistance --- ESBL-producing Klebsiella pneumoniae --- urinary tract infection --- clinical impact --- economic impact --- ventilator-associated pneumonia --- Klebsiella spp. --- Escherichia spp. --- pulsed-field gel electrophoresis (PFGE) --- endogenous infection --- methicillin-resistant --- porcine model --- methicillin-resistant Staphylococcus aureus (MRSA) --- long term care facilities (LTCF) --- multidrug resistance (MDR) --- enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) --- ESBL --- PCR --- primer --- antimicrobial resistance --- infection prevention and control --- antimicrobial stewardship --- hospital --- cluster analysis --- principal component analysis
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There has been much speculation about a possible antibiotic Armageddon; this would be the result of having untreatable post-operative infections, and similarly untreatable complications after chemotherapy. The now famous “O’Neill Report” (https://amr-review.org/) suggests that more people could die from resistant bacterial infections by 2050 than from cancer. We are still learning about all the subtle drivers of antibiotic resistance, and realizing that we need a single “whole of health” co-ordinated policy. We ingest what we sometimes feed to animals. There do not seem to be any new classes of antibiotics on our horizon. Perhaps something that has been around “forever” will come to our rescue—bacteriophages! Nevertheless, we have to do things differently, use antibiotics appropriately, for the correct indication, for the correct duration and with the correct dose, and with that, practice good antibiotic stewardship. Whilst by no means comprehensive, this book does cover some of the many topics of antibiotic stewardship. It also addresses some of the older antibiotics, some new combinations, and even some new agents. Last, and by no means least, there are two excellent articles on bacteriophages.
Medicine --- Antimicrobial resistance --- antibiotics --- antimicrobial stewardship --- inappropriate prescribing --- days of therapy --- Start Smart then Focus --- piperine --- piperlongumine --- antibacterial --- antifungal --- synergy --- non-target feed --- florfenicol --- thiamfenicol --- chloramfenicol --- HPLC–MS/MS --- validation --- swine --- out-of-hours care --- primary care --- quality of care --- quality indicators --- practitioners cooperative --- antibiotic stewardship --- fluoroquinolones --- guidelines --- urinary tract infections --- quality improvement --- general practitioners --- guideline --- health inequalities --- health equity assessment tool --- public health --- Enterobacteriaceae --- carbapenem-resistant --- CRE --- antibiotic resistance --- antimicrobials --- bacteriophages --- biofilms --- novel antimicrobials --- Antibiotics --- resistance --- broad-spectrum agents --- hospital epidemiology --- antibiotic utilization --- infection control --- infection prevention --- Pseudomonas aeruginosa --- Acinetobacter baumannii --- extended-spectrum beta-lactamases --- carbapenem-resistant Enterobacteriaceae --- methicillin-resistant Staphylococcus aureus --- clinical trials --- infectious disease --- phage therapy --- silver complexes --- camphorimine --- anti-Candida activity --- antifungals --- antibacterials --- efflux inhibitors --- efflux pumps --- erm(41) --- mutations --- mycobacteria --- verapamil --- actinomycetes --- bioactivity --- polyketides --- polyketide synthases --- biosynthesis --- antimicrobial resistance --- economic evaluation --- cost-utility analysis --- cost-effectiveness analysis --- policy analysis --- One Health --- Singapore --- antibiotic prescribing --- implementation --- behavior change --- stakeholder consultation --- n/a --- HPLC-MS/MS
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Antimicrobial Stewardship & Healthcare Epidemiology (ASHE) is a fully Gold Open Access journal that invites submissions of original investigations that will contribute to the fields of antimicrobial stewardship and the prevention of healthcare-associated infections, as well as other areas of quality improvement affecting health systems, with the ultimate goal of improving healthcare safety. Covered topics include the following broad areas of interest: infection prevention, antimicrobial stewardship, healthcare epidemiology, diagnostic stewardship, healthcare worker vaccination, public health policy, and occupational health concerns including blood-borne pathogen exposure prevention.
antimicrobial stewardship --- infection prevention --- healthcare safety --- healthcare epidemiology --- public health policy --- Cross Infection --- Epidemiological Methods --- Anti-Infective Agents --- Anti-infective agents --- Epidemiology --- Public health --- Community health services --- Social medicine --- Anti-infective agents. --- Epidemiology. --- Antiinfectieux --- Épidémiologie --- Santé publique --- Antiinfectieux. --- Épidémiologie. --- prevention & control --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Microbicides --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agent --- Anti Infective Agents --- Anti Microbial Agent --- Anti Microbial Agents --- Infections --- Parasites --- Epidemiologic Method --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Diseases --- Antiinfective agents --- Antimicrobial agents --- Antimicrobial drugs --- Antimicrobials --- Drugs --- Neighborhood health centers --- Regional medical programs --- methods --- Social medicine. --- Public health. --- Community health services. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Medical care --- Medical sociology --- Medicine, Social --- Medicine --- Public welfare --- Sociology --- Medical ethics --- Medical sociologists --- Social aspects
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The scope of the Special Issue is research and reviews on evaluations of current practice, innovations in medication management, developments in therapeutics, and pharmaceutical science research that informs and improves practice and administration, as well as the social and administrative pharmacy. We will mainly feature original research, reviews, short reports, and clinical studies, but also case reports, descriptive/how-to, and commentary submissions for consideration.
Medicine --- Pharmaceutical industries --- older adults --- polypharmacy --- internal medicine ward --- community pharmacy --- drug disposal --- unused medication --- environment --- awareness --- practice --- ambulatory care facilities --- health workforce --- pharmacists --- Taiwan --- Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) --- National Health Service (NHS) --- Chief Pharmaceutical Officer’s Global Health Fellowship --- CPhOGH Fellows --- CwPAMS --- pharmacy --- fellowship --- health partnerships --- antimicrobial resistance (AMR) --- global health --- leadership --- non-prescription medicines --- emergency contraception --- community pharmacies --- information gathering --- availability --- pricing --- mystery calls --- ulipristal acetate --- levonorgestrel --- Germany --- e-prescription --- prescription writing --- Jazan --- Saudi Arabia --- prescription errors --- medicine consumption --- defined daily dose --- adolescents and young adults --- cancer patients --- fragility --- pain --- MUR --- medication review --- barriers --- pharmacist --- pregabalin --- abuse --- community pharmacists --- reproductive health --- contraception --- emergency contraceptives --- patient education --- biosensing technology --- digital medicine system --- medication adherence --- medication event monitoring system --- nonadherence --- prescription opioids --- mortality --- standardized mortality ratio --- underlying cause of death --- prescriptions --- community pharmacy services --- emergency prescribing --- pharmacy practice --- pharmacy law and regulation --- COVID-19 --- additional monitoring --- black triangle --- adverse event reporting --- pharmacovigilance --- intervention --- outcomes --- systematic review --- pharmacy education --- decision to study in pharmacy --- selecting pharmacy as a first choice --- pharmacogenomics --- learning activity --- asynchronous learning --- virtual learning --- student survey --- Program of All-Inclusive Care for the Elderly --- adverse drug events --- medication-related problems --- drug-related problems --- medication safety --- Medicare --- Medicaid --- financial management --- pharmacy management --- business --- entrepreneurship --- pharmacy students --- perception --- attitudes --- ability --- interprofessional --- simulation --- acute care --- nursing --- students --- standardized patients --- high fidelity --- SPICE-R2
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