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Biophysical chemistry is one of the most interesting interdisciplinary research fields. Some of its different subjects have been intensively studied for decades. Now the field attracts not only scientists from chemistry, physics, and biology backgrounds but also those from medicine, pharmacy, and other sciences. We aimed to start this version of the book Biophysical Chemistry from advanced principles, as we include some of the most advanced subject matter, such as advanced topics in catalysis applications (first section) and therapeutic applications (second section). This led us to limit our selection to only chapters with high standards, therefore there are only six chapters, divided into two sections. We have assumed that the interested readers are familiar with the fundamentals of some advanced topics in mathematics such as integration, differentiation, and calculus and have some knowledge of organic and physical chemistry, biology, and pharmacy. We hope that the book will be valuable to graduate and postdoctoral students with the requisite background, and by some advanced researchers active in chemistry, biology, biochemistry, medicine, pharmacy, and other sciences.
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Thermodynamics. --- Physical biochemistry. --- Bioenergetics.
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Bioenergetics --- Bioénergétique --- Bioénergétique --- Physical biochemistry
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Molecular biology. --- Nucleic acids. --- Physical biochemistry --- Proteins
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Physical biochemistry --- Biochimie physique --- Biochemistry. --- Biochimie physique.
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The replacement of the bridging H atom in H-bonds by a multitude of other, more electronegative, atoms has led to the rapidly growing study of related noncovalent bonds generally known as halogen, chalcogen, and pnicogen bonds. It has recently been recognized that elements of the tetrel family (C, Si, Ge, Sn, Pb) also engage in such bonds, wherein the tetrel atom serves as an electron acceptor to an incoming Lewis base, and that these bonds can be quite strong. This type of bond has the potential to be of importance comparable even to that of the well-researched H-bond, as it may be far more prevalent than has been realized, perhaps a common feature of chemical and biological systems too numerous to mention. The articles included in this volume delve into the many facets of tetrel bonds: the factors determining their strength, their geometrical requirements, various phenomena in which they play an outsized role, and the means by which they can be detected and measured.
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Thermodynamics. --- Gibbs' free energy. --- Bioenergetics. --- Physical biochemistry.
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Chemical Biophysics provides an engineering-based approach to biochemical system analysis for graduate-level courses on systems biology, computational bioengineering and molecular biophysics. It is the first textbook to apply rigorous physical chemistry principles to mathematical and computational modeling of biochemical systems for an interdisciplinary audience. The book is structured to show the student the basic biophysical concepts before applying this theory to computational modeling and analysis, building up to advanced topics and research. Topics explored include the kinetics of nonequilibrium open biological systems, enzyme mediated reactions, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems. End-of-chapter exercises range from confidence-building calculations to computational simulation projects.
Physical biochemistry. --- Computational biology. --- Biological systems --- Mathematics.
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Physical biochemistry. --- Biophysical chemistry --- Biochemistry --- Physical organic chemistry
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Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With around 280 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/Boal.
Cells --- Physical biochemistry --- Mechanical properties --- Physical biochemistry. --- Biophysical chemistry --- Biochemistry --- Physical organic chemistry --- Cell mechanics --- Cellular mechanics --- Biomechanics --- Mechanical properties. --- Biochimie physique --- Cells - Mechanical properties
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