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Phosphatidylcholine-preferring phospholipase C from "B. cereus" : function, structure, and mechanism
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Year: 2001

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New functions from old scaffolds : how nature reengineers enzymes for new functions
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Year: 2001

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Cyclic nucleotide phosphodiesterases : relating structure and function
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Year: 2001

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"Bacillus thuringiensis" insecticidal proteins : molecular mode of action
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Year: 1998

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Structure-activity relationships of protein and polypeptide hormones. 002. Part II
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ISBN: 9021901722 9789021901725 Year: 1972 Volume: 241 Publisher: Amsterdam : Elsevier Science Publishers, Excerpta Medica Medical Communications Division,

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Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino : Pharmaceutical chemistry: Lectures by prof. Ettore Novellino
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ISBN: 9788868870157 Year: 2017 Publisher: FedOA - Federico II University Press

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For thousands of years, pharmacological knowledge coming from natural remedies, has been handed down from generation to generation, without any awareness of the ways in which preparations are made to face diseases. The advent of pharmaceutical chemistry and of the modern drug industry turned that lack of awareness into a scientific knowledge that changed the destiny of the human race. The twenty-eight chapters of this book, are taken from the lectures held by Professor Ettore Novellino every year in his course “Pharmaceutical Chemistry and Toxicology 2”. The first chapters address the basic notions of drugs, homeostasis, pharmacopoeia, and receptor; then, the different pharmaceutical classes are introduced by analyzing their pharmacological and chemical aspects. In particular, the structural study of the interaction between drugs and receptors or biological enzymes gives the fundamentals to connect the chemical and stereochemical properties of a compound family, with the biological activity, a correlation better known as Quantitative Structure-Activity Relationship (QSAR). Several examples of the synthesis of some of the most historically renown drugs, provided at the end of each chapter, integrate the book.


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Structure and function of membrane proteins : proceedings of the International Symposium on Structure and Function of Membrane Proteins held in Selva di Fasano (Italy), May 23-26, 1983
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ISBN: 0444805400 Year: 1983 Publisher: Amsterdam New York : New York, N.Y. : Elsevier Science Publishers Sole distributors for the USA and Canada, Elsevier Science Pub. Co.,

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Steroid receptors and antihormones
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ISBN: 0897669371 089766938X 9780897669382 Year: 1995 Volume: 761 Publisher: New York, NY : New York Academy of Sciences,


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QSAR in safety evaluation and risk assessment
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ISBN: 044315340X 0443153396 9780443153402 9780443153396 Year: 2023 Publisher: [S.l.] Academic Press

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QSAR in Safety Evaluation and Risk Assessment provides comprehensive coverage on QSAR methods, tools, data sources, and models focusing on applications in products safety evaluation and chemicals risk assessment. Organized into five parts, the book covers almost all aspects of QSAR modeling and application. Topics in the book include methods of QSAR, from both scientific and regulatory viewpoints; data sources available for facilitating QSAR models development; software tools for QSAR development; and QSAR models developed for assisting safety evaluation and risk assessment. Chapter contributors are authored by a lineup of active scientists in this field. The chapters not only provide professional level technical summarizations but also cover introductory descriptions for all aspects of QSAR for safety evaluation and risk assessment.

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