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Biopharmaceutics. --- Pharmaceutical chemistry. --- Structure-activity relationships (Biochemistry) --- Pharmaceutical chemistry --- Biopharmaceutics --- Chemistry, Pharmaceutical --- Structure-Activity Relationship --- Chimie pharmaceutique --- Biopharmacie. --- Chimie pharmaceutique. --- Relations structure-activité (Biochimie)
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Vaso-occlusive disorders including unstable angina, myocardial infarction, transient ischemic attacks, stroke and peripheral artery disease remain the major sources of morbidity and mortality in western civilization. Platelet activation and resulting platelet aggregation play a major role in the pathogenesis of these thromboembolic diseases. Recognition of the contribution of platelets to the pathophysiology of cardiovascular disease has provided impetus for the continued search for new antiplatelet agents.
Pharmaceutical chemistry --- Congresses --- Chemistry --- Physical sciences --- Chimie pharmaceutique --- Platelet Aggregation Inhibitors
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Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure-activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any. This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents. Includes current research focused on drug resistance and methods to overcome problems Outlines synthetic schemes and metabolic pathways of chemotherapeutic agents Discusses molecules under clinical trials and newly approved drugs.
Pharmaceutical chemistry. --- Chemotherapy. --- Anti-infective agents. --- Drug Therapy --- Chemistry, Pharmaceutical --- Antineoplastic Agents --- Anti-Infective Agents --- chemistry --- Chimie pharmaceutique. --- Chimiothérapie.
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Chemistry, Pharmaceutical --- Pharmacology --- Pharmaceutical chemistry --- Chemistry, Pharmaceutical. --- Pharmacology. --- Chimie pharmaceutique --- Medische chemie. --- Farmacochemie. --- Geneesmiddelen. --- Pharmacologies --- Pharmaceutical Preparations --- Chemistry, Pharmaceutic --- Pharmaceutic Chemistry --- Pharmaceutical Chemistry --- Medicinal Chemistry --- Chemistry, Medicinal --- pharmacology
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Antitumor chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumor drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents,
Oncology. Neoplasms --- Antineoplastic Agents --- Neoplasms --- Cancer --- Drugs --- Pharmaceutical chemistry --- Médicaments --- Chimie pharmaceutique --- chemistry. --- pharmacology. --- drug therapy. --- Chemotherapy --- Design --- Chimiothérapie --- Conception --- Pharmaceutical chemistry. --- Chemotherapy. --- Design.
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Chemistry --- Chemistry, Pharmaceutical --- Pharmaceutical chemistry --- Chimie pharmaceutique --- Periodicals. --- Périodiques --- Periodicals --- Chemistry, Pharmaceutical. --- Pharmaceutical chemistry. --- Chimie pharmaceutique. --- Pharmaceutical Chemistry --- Pharmacy and Pharmacology --- Health Sciences --- Chemistry. --- Pharmacy and Pharmacology. --- Health Sciences. --- Périodiques --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry, Pharmaceutic --- Pharmaceutic Chemistry --- Medicinal Chemistry --- Chemistry, Medicinal --- Pharmacy, Therapeutics, & Pharmacology --- Pharmaceutical chemistry - Periodicals. --- Chemistry, Pharmaceutical - periodicals.
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Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists with little or no background in medicinal chemistry. These chemists must acquire a good knowledge of medicinal chemistry during their first years in the pharmaceutical/drug discovery industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. The book reviews practical aspects of Medicinal Chemistry, emphasising the daily problems met by the medicinal chemist when dealing with lead discovery/identification methodologies, with structure-activity
Pharmaceutical chemistry. --- Drugs --- Chimie pharmaceutique --- Médicaments --- Design. --- Conception --- Chemistry, Pharmaceutical --- Médicaments --- Drug design --- Pharmaceutical design --- Drug development --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Drugs - Design. --- Chemistry, Pharmaceutical - Handbooks. --- Acqui 2006
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biologically active compounds --- medicinal chemistry --- drug-receptor interactions --- natural products --- traditional chinese medicine (tcm) --- Chemistry, Pharmaceutical --- Drug Discovery --- Pharmaceutical chemistry --- Pharmacology --- Pharmaceutical chemistry. --- Pharmacology. --- Chimie pharmaceutique --- Pharmacologie --- Chimie pharmaceutique. --- Pharmacologie. --- pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Drug Prospecting --- Discovery, Drug --- Prospecting, Drug --- High-Throughput Screening Assays --- Bioprospecting --- Chemistry, Pharmaceutic --- Pharmaceutic Chemistry --- Pharmaceutical Chemistry --- Medicinal Chemistry --- Chemistry, Medicinal --- Physiological effect
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"An international journal of medicinal chemistry and pharmaceutical chemistry."
Pharmaceutical chemistry --- Pharmacology --- Chemistry, Pharmaceutical --- Drug Therapy --- Chemistry, Pharmaceutical. --- Drug Therapy. --- Chimie pharmaceutique --- Pharmacologie --- Pharmaceutical chemistry. --- Pharmacology. --- Périodiques. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Therapy, Drug --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Disease --- Pharmaceutical Preparations --- Pharmacologic Actions --- Chemistry, Pharmaceutic --- Pharmaceutic Chemistry --- Pharmaceutical Chemistry --- Medicinal Chemistry --- Chemistry, Medicinal --- Physiological effect --- drug therapy --- therapeutic use --- Chemotherapy. --- Chimie pharmaceutique. --- Chimiothérapie. --- Periodicals. --- Drug therapy --- Therapeutics
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Now in its third edition, this classic reference is the one-stop-shop for information on the foundations of medicinal chemistry for pharmaceutical researchers who are involved in drug development & discovery but who do not have a background in medicinal chemistry. Wermuth aids pharmaceutical researchers and chemists in making faster, more accurate identifications of the active substances that could potentially treat the disorder they are researching. New chapters on Drug Absorption & Transport give pharmaceutical scientists information on how potential drugs can move through the drug discovery
Pharmaceutical chemistry --- Drugs --- Chimie pharmaceutique --- Médicaments --- Design --- Conception --- Pharmaceutical chemistry. --- Chimie pharmaceutique (Trad. du MeSH) --- Modèles chimiques (Trad. du MeSH) --- Chimie pharmaceutique. --- Pharmaceutical Preparations --- Design. --- Conception. --- chemistry. (MeSH - aucune traduction) --- Chemical models. --- Drugs. --- Pharmaceutical Preparations. --- Chemistry, Pharmaceutical --- Models, Chemical --- Chemistry --- Models, Theoretical --- Pharmacology --- Chemicals and Drugs --- Investigative Techniques --- Biological Science Disciplines --- Natural Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Médicaments --- Drug design --- Pharmaceutical design --- Drug development --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Cellular signal transduction. --- Mechanotransduction, Cellular --- Cellular Mechanotransduction --- Mechanosensory Transduction --- Signal Transduction, Mechanical --- Mechanical Signal Transduction --- Transduction, Mechanosensory --- Podosomes --- Mechanoreceptors --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Signal Transduction. --- Transduction du signal cellulaire --- Cellular signal transduction --- ELSEVIER-B EPUB-LIV-FT --- Cellular control mechanisms. --- Cell regulation --- Biological control systems --- Cell metabolism --- chemistry --- Modèles chimiques (Trad. du MeSH) --- chemistry.
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