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The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of in

Antigens --- Immunity. --- Immunity --- Immunoglobulins --- Immunology --- Genetic aspects. --- Physiological aspects.

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Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of p

Fc receptors. --- Immune response. --- Anti-antibodies. --- Receptors, Fc --- Immunoglobulins --- Immunology --- Cell receptors --- Lymphocytes --- Macrophages --- Immunoglobulins. --- Antibody diversity.

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This volume is THE definitive, completely up-to-date, reference work for ALL researchers and clinicians working in autoimmunity. Up-to-Date: This is a timely critical review of more than 100 autoantibodies by leading experts in their respective fields, and includes many recent references. International Experts: The 120 Chapters have been written by the top international cadre of authors who have provided structured, expert contributions. Comprehensive: A total comprehensive perspective on the processes which induce, inhibit or otherwise affect autoantibodies in human

Immunology. Immunopathology --- Autoantibodies. --- Autoimmune Diseases --- etiology. --- Immunoglobulins. --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Immunoglobulins --- Autoimmunity

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Lectins: Analytical Technologies covers both analytical and biological aspects of lectins (functional carbohydrate (complex sugar) recognition proteins) and provides researchers in the field with a resource containing background information and 'look-up' tables detailing lectin specificity and structures. Also included are methods and practical tips for designing new lectins from existing non-lectin proteins, automated approaches to lectin proteomics and high resolution mass spectrometry techniques. This book will be of interest to both novice and advanced researchers in biom

Lectins. --- Immunoglobulins. --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Protectins --- Receptor-specific proteins --- Hemagglutinin --- Immunoglobulins

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Autoimmune diseases are characterized by the occurrence of antibodies reacting with self constituents of the body. This exciting new reference is an exhaustive review of the main autoantibodies identified up to now, with particular emphasis on those autoantibodies that display a clinical value. Each chapter is focussed on a single family of autoantibodies by reviewing their historical notes, definition, origin and source(s) of the antigen(s) recognized, genetic associations, pathogenic mechanisms that are mediated, method(s) of detection and clinical utility (disease prevalence/association, di

Autoantibodies --- Immunoglobulins --- Autoimmunity --- Autoantibodies. --- Biology. --- Life sciences --- Biomass --- Life (Biology) --- Natural history