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Periodical
Platelets.
Author:
ISSN: 13691635 09537104 Year: 1990 Publisher: [Abingdon, Oxfordshire] : Carfax International Publishers,

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Abstract

Platelet Function : Assessment, Diagnosis, and Treatment
Authors: --- ---
ISBN: 1280831839 9786610831838 1592599176 1588292444 1617374474 Year: 2005 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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Abstract

Platelet function, or clot formation, is difficult to assess, but extremely important because inadvertent or excessive platelet activation underlies many common cardiovascular disorders, such as myocardial infarction, unstable angina, and stroke. In Platelet Function: Assessment, Diagnosis, and Treatment, a panel of leading researchers and clinicians review the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed. Comprehensive and state of the art, Platelet Function: Assessment, Diagnosis, and Treatment offers vascular researchers and clinicians a sound foundation for understanding platelet biology, assessing thrombotic risk in patients, and determining the rational dosing of antiplatelet agents.

Thrombin : Physiology and Disease
Authors: --- --- --- ---
ISBN: 0387096361 1441918779 9786612824951 1282824953 038709637X 354009637X 3540347534 3540096361 9783540096368 9780387096360 9783540096375 Year: 2009 Volume: 19 Publisher: New York, NY : Springer New York : Imprint: Springer,

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Abstract

It has become increasingly evident in recent years that, apart from the key role that thrombin plays in the blood coagulation cascade, thrombin also elicits cellular actions via the activation of proteinase-activated receptors, which are present in many cell types. These effects of thrombin are seen in a variety of physiological as well as pathological phenomena, including vascular development and physiology, tumor progression and metastasis, neuronal functions, inflammation, angiogenesis. Thrombin: Physiology and Disease, edited by Michael E. Maragoudakis and Nikos E. Tsopanoglou, emphasizes the new developments in this important field of research and provides the basis for translating these findings into therapeutic targets.".

Keywords

Optical communications. --- Semiconductors. --- Thrombin --- Blood --- Thrombolytic therapy --- Receptors, G-Protein-Coupled --- Platelet Membrane Glycoproteins --- Receptors, Peptide --- Serine Endopeptidases --- Receptors, Proteinase-Activated --- Blood Coagulation Factors --- Biological Science Disciplines --- Receptors, Cell Surface --- Serine Proteases --- Membrane Glycoproteins --- Blood Proteins --- Endopeptidases --- Biological Factors --- Natural Science Disciplines --- Receptors, Thrombin --- Physiology --- Peptide Hydrolases --- Membrane Proteins --- Chemicals and Drugs --- Disciplines and Occupations --- Proteins --- Glycoproteins --- Hydrolases --- Amino Acids, Peptides, and Proteins --- Enzymes --- Enzymes and Coenzymes --- Human Anatomy & Physiology --- Electrical & Computer Engineering --- Medicine --- Health & Biological Sciences --- Engineering & Applied Sciences --- Oncology --- Telecommunications --- Physiological effect --- Coagulation --- Thrombin. --- Thrombolytic therapy. --- Physiological effect. --- Coagulation. --- Fibrinolytic therapy --- Thrombolysis --- Thrombosis --- Blood coagulation --- Clotting of blood --- Coagulation of blood --- Fibrinogenase --- Thrombase --- Thrombosin --- Chemotherapy --- Clotting --- Large scale systems --- Systèmes de grandes dimensions --- Systèmes de grandes dimensions --- Halvledarkomponenter --- Halvledarkomponenter. --- Medicine. --- Cancer research. --- Human physiology. --- Pharmacology. --- Epidemiology. --- Biochemistry. --- Biomedicine. --- Human Physiology. --- Cancer Research. --- Pharmacology/Toxicology. --- Biochemistry, general. --- Fibrinolysis --- Hemostasis --- Anticoagulants (Medicine) --- Coagulase --- Blood coagulation factors --- Hemostatics --- Serine proteinases --- Economics --- Computer engineering --- Mathematical models --- System theory --- Economie politique --- Congresses --- Modèles mathématiques --- Congrès --- Oncology. --- Toxicology. --- Diseases --- Public health --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Human biology --- Human body --- Composition --- Toxicology --- Drug effects --- Medical pharmacology --- Drugs --- Pharmacy --- Cancer research --- Economics - Mathematical models - Congresses --- Large scale systems - Congresses

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