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Infertility is an important health problem affecting around 15% of couples worldwide, with profound psycho-social consequences and impairment of patients’ quality of life. It has been shown that the male factor is solely and partially implicated in 20-50% of the cases of infertility. Male infertility is a complex issue that can be related to a variety of congenital or acquired factors that lead to a decline in the quantity and/or the quality of semen. Over the recent years, there have been major advances in basic understanding of the factors that regulate male fertility, the diagnostic tests for assessment of male fertility potential, and the therapeutic options for the management of male subfertility/infertility. However, despite advances in technologies and diagnostic methods in the field of andrology, there remains a significant subset of these subfertile men who are classified as having unexplained or idiopathic male infertility. In addition, there are ongoing debates and controversies on the clinical management of infertile men under certain conditions like varicocele, genital tract inflammation/infection or non-obstructive azoospermia. This book discusses advances in cellular, molecular, and genetic aspects of spermatogenesis and sperm evaluation in the context of clinical scenarios. It also addresses clinical dilemmas and controversies through a discussion of the basic science underlying these conditions. The authors form an impressive international collaboration to provide a unique perspective that specializes in all key areas of andrology. Current and Future Advances in Male Infertility provides insights into strategies to reduce the burden of male gonadotoxins, to enhance men’s fecundity and to help optimize the care of infertile men. It aims to bridge the gap between researchers and clinicians by integrating basic science and clinical application.

Infertility, Male.

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Despite the fact that about half of infertility problems stem from male factors, gynecologists are often the first health care providers to perform the initial assessment of the infertile couple. For this reason, it is critical that gynecologists and reproductive medicine specialists remain up to date on the primary conditions that cause male infertility, as well as current diagnostic tools and treatment options of both natural and assisted conception. From diagnosis through treatment, Male Infertility: Management of Infertile Men in Reproductive Medicine offers expert, straightforward guidance on the pathophysiology and management of male infertility for clinicians who assist couples early in the process of trying to conceive.

Infertility, Male. --- Reproductive health. --- Infertility, Male --- Andrology --- Reproductive Health --- Reproductive Medicine

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Andrology --- Fertility, Human --- Infertility, Male --- Fertility --- Genital Diseases, Male --- Genitalia, Male --- Andrology. --- Infertility, Male. --- Male infertility --- Male sterility --- Sterility, Male --- Reproductive Medicine. --- Men's Health. --- Generative organs, Male --- Infertility --- Human reproduction --- Men --- Diseases --- Endocrine aspects --- Physiology

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Male Infertility: Problems and Solutions provides a summary of state of the art developments in male infertility for both new and experienced practitioners. Written in a clear, concise and readable style, this volume allows the reader to obtain rapid answers to this challenging medical issue. Special emphasis is placed on diagnostic and treatment algorithms. Topics covered include interpretation of semen analysis and advanced testing, endocrine and genetic evaluation, diagnosis of azoospermia as well as an up-to-date interpretation and analysis of the many new therapies available for the treatment of male factor infertility. Male Infertility: Problems and Solutions provides rapid acquisition of pertinent background and development of management plans through the use of concise discussion and treatment algorithms and thus will be of great value to general urologists, gynecologists, primary care providers and allied health providers who manage infertility in both men as well as women.

Infertility, Male -- Diagnosis. --- Infertility, Male -- Treatment. --- Infertility, Male. --- Infertility, Male --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Infertility --- Genital Diseases, Male --- Diagnosis --- Male Urogenital Diseases --- Diseases --- Medicine --- Health & Biological Sciences --- Urology & Nephrology --- Treatment. --- Male infertility --- Male sterility --- Sterility, Male --- Medicine. --- Reproductive medicine. --- Surgery. --- Urology. --- Medicine & Public Health. --- Reproductive Medicine. --- Generative organs, Male --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Surgery, Primitive --- Genitourinary organs --- Health aspects --- Reproductive health.

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Infertility is a common and severe health problem affecting roughly 7% of the male population. It is likely that the majority of those patients have genetic abnormalities that are the cause of their infertility. In The Genetics of Male Infertility, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms. Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

Infertility, Male --- Spermatogenesis --- Genetic aspects --- Formation of spermatozoa --- Spermatozoa --- Gametogenesis --- Male infertility --- Male sterility --- Sterility, Male --- Generative organs, Male --- Infertility --- Formation --- Diseases