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This open access book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results. Authoritative and comprehensive, Evolutionary Genomics: Statistical and Computational Methods, Second Edition aims to serve both novices in biology with strong statistics and computational skills, and molecular biologists with a good grasp of standard mathematical concepts, in moving this important field of study forward.

Bioinformatics. --- Genetics. --- Evolution (Biology). --- Genetics and Genomics. --- Evolutionary Biology. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Data processing --- Genètica evolutiva --- Genòmica --- Models matemàtics --- Bioinformàtica --- Informàtica biològica --- Ciències de la informació --- Biologia computacional --- Models (Matemàtica) --- Models experimentals --- Models teòrics --- Mètodes de simulació --- Anàlisi de sistemes --- Mètode de Montecarlo --- Modelització multiescala --- Models economètrics --- Models lineals (Estadística) --- Models multinivell (Estadística) --- Models no lineals (Estadística) --- Programació (Ordinadors) --- Simulació per ordinador --- Teoria de màquines --- Models biològics --- Genètica molecular --- Metagenòmica --- Nutrigenòmica --- Genomes --- Genètica --- Life sciences --- Bioinformatics --- Genetics

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This open access book deals with a rich variety of taxis-type cross-diffusive equations. Particularly, it intends to show the key role played by quasi-energy inequality in the derivation of some necessary a priori estimates. This book addresses applied mathematics and all researchers interested in mathematical development of reaction-diffusion theory and its application and can be a basis for a graduate course in applied mathematics.

Boundary value problems. --- Chemotaxis --- Navier-Stokes equations. --- Mathematical models. --- Equations, Navier-Stokes --- Differential equations, Partial --- Fluid dynamics --- Viscous flow --- Chemiotaxis --- Chemotropism --- Biochemistry --- Growth --- Taxes (Biology) --- Boundary conditions (Differential equations) --- Differential equations --- Functions of complex variables --- Mathematical physics --- Initial value problems --- Problemes de contorn --- Quimiotaxi --- Models matemàtics --- Equacions de Navier-Stokes --- Navier-Stokes (Equacions) --- Dinàmica de fluids --- Equacions en derivades parcials --- Models (Matemàtica) --- Models experimentals --- Models teòrics --- Mètodes de simulació --- Anàlisi de sistemes --- Mètode de Montecarlo --- Modelització multiescala --- Models economètrics --- Models lineals (Estadística) --- Models multinivell (Estadística) --- Models no lineals (Estadística) --- Programació (Ordinadors) --- Simulació per ordinador --- Teoria de màquines --- Models biològics --- Bioquímica --- Creixement --- Problemes de valor límit --- Equacions diferencials --- Física matemàtica --- Funcions de variables complexes --- Dispersió (Matemàtica) --- Equacions de Von Kármán --- Problema de Dirichlet --- Problema de Neumann --- Problemes de Riemann-Hilbert --- Problemes de valor inicial --- Reaction-Diffusion --- Haptotaxis --- Navier-Stokes --- Cancer invasion --- Coral fertilization --- Sensity-suppressed motility --- Oncolytic virotherapy --- Foraging scrounging interplay

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This open access book collects expert contributions on actuarial modelling and related topics, from machine learning to legal aspects, and reflects on possible insurance designs during an epidemic/pandemic. Starting by considering the impulse given by COVID-19 to the insurance industry and to actuarial research, the text covers compartment models, mortality changes during a pandemic, risk-sharing in the presence of low probability events, group testing, compositional data analysis for detecting data inconsistencies, behaviouristic aspects in fighting a pandemic, and insurers' legal problems, amongst others. Concluding with an essay by a practicing actuary on the applicability of the methods proposed, this interdisciplinary book is aimed at actuaries as well as readers with a background in mathematics, economics, statistics, finance, epidemiology, or sociology.

Assegurances --- Models matemàtics --- Estadística matemática --- Seguretat social --- Epidèmies --- Endèmias --- Malalties epidèmiques --- Pandèmies --- Pestes --- Epidemiologia --- Còlera --- Epidèmia de grip, 1918-1919 --- Febre groga --- Pandèmia de COVID-19, 2020 --- -Pesta --- Pesta Negra --- Assegurances obreres --- Assegurances socials --- Estat i assegurances --- Dret social --- Pensions --- Seguretat econòmica --- Assegurances de malaltia --- Indemnitzacions als treballadors --- Subsidi d'atur --- Subsidi de maternitat --- Benestar social --- Pensions no contributives --- Plans de pensions --- Distribució de la renda --- Renda mínima --- Estadística descriptiva --- Inferència estadística --- Matemàtica estadística --- Mètodes estadístics --- Estadística --- Anàlisi d'error (Matemàtica) --- Anàlisi de regressió --- Anàlisi de sèries temporals --- Anàlisi de variància --- Anàlisi multivariable --- Anàlisi seqüencial --- Astronomia estadística --- Correlació (Estadística) --- Dependència (Estadística) --- Estadística no paramètrica --- Estadística robusta --- Física estadística --- Mètode dels moments (Estadística) --- Models lineals (Estadística) --- Models no lineals (Estadística) --- Teoria de l'estimació --- Teoria de la predicció --- Tests d'hipòtesi (Estadística) --- Biometria --- Mostreig (Estadística) --- Models (Matemàtica) --- Models experimentals --- Models teòrics --- Mètodes de simulació --- Anàlisi de sistemes --- Mètode de Montecarlo --- Modelització multiescala --- Models economètrics --- Models multinivell (Estadística) --- Programació (Ordinadors) --- Simulació per ordinador --- Teoria de màquines --- Models biològics --- Finances privades --- Assegurances aèries --- Assegurances col·lectives --- Assegurances contra els riscs de guerra --- Assegurances d'accidents --- Assegurances d'automòbils --- Assegurances d'incendis --- Assegurances d'invalidesa --- Assegurances de crèdit --- Assegurances de l'empresa --- Assegurances de mercaderies --- Assegurances de responsabilitat civil --- Assegurances de viatgers --- Assegurances de vida --- Assegurances marítimes --- Companyies d'assegurances --- Gestió del risc --- Primes (Assegurances) --- Reassegurances --- Agents d'assegurances --- Risc (Assegurances) --- Epidemics. --- Insurance --- Social security. --- Mathematical models. --- Statistical methods. --- Insurance, Social --- Insurance, State and compulsory --- Social insurance --- Income maintenance programs --- Actuarial statistics --- Insurance statistics --- Disease outbreaks --- Diseases --- Outbreaks of disease --- Pestilences --- Communicable diseases --- Mathematics --- Outbreaks --- Epidemics --- Risk --- Social protection --- Actuarial modelling --- Open Access