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Constructed wetlands (CWs) are engineered phytoremediation ecotechnologies. Herein, the two main biotic components, namely, plants and the bacterial community, work synergistically to remove a wide range of pollutants from wastewater. CWs have been used as sole treatment systems or as integrated modules within other types of wastewater-treatment plants (WWTPs), e.g., as tertiary treatment units. This Special Issue and Book gathers and appraises recent research outcomes regarding natural wetlands (i.e., mangroves) and engineered wetlands (constructed/floating systems), and highlights the underlying pollutant-degradation pathways and mechanisms for a wide range of organic and inorganic contaminants.
phytoremediation --- heavy metal --- aquatic plants --- floating aquatic plants --- wastewater treatment --- floating treatment wetlands --- Cyperus laevigatus L --- diesel oil --- plant-bacteria synergism --- toxicity --- bio-augmentation --- dye degradation --- bacteria --- Phragmites australis --- acetaminophen --- mangrove sediments --- biodegradation --- aerobic conditions --- anaerobic conditions --- water --- plants --- microbes --- pollutants --- textile effluent --- hydroponic root mats --- plant-bacteria partnership --- detergents --- wastewater --- livestock wastewater --- Typha latifolia L. --- V-SSF systems --- total nitrogen --- COD --- total suspended solids --- constructed wetlands --- agricultural runoff --- chemicals of emerging concern --- veterinary antibiotics --- antibiotic resistant genes --- n/a
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There is some talk about an antibiotic Armageddon due to quickly developing resistance towards commercially available antibiotics. For the most part, the classical antibiotic pipeline has dried up, and antibiotic resistance to any new drugs quickly develops. It is here that metal-based antimicrobials can step forward as possible solutions in this antimicrobial resistance era. The biological targets of metal atoms are more diverse, thus making it more difficult for bacteria to develop resistance compared with classical antibiotics. The metal silver has been used since antiquity for wound healing and water purification. At present, it is the most prevalent antimicrobial metal used in healthcare, industry, and consumer products. Silver is being used in the form of ionic salt, colloids, or in specific nanomaterials, and as described in this book, it can be applied as mixtures with other antimicrobials or coating composites. The different formulations are explored for their efficacy against a variety of problems related to agricultural and medical infections. Whilst by no means exhaustive, this book nicely highlights the present directions in silver-based antimicrobial research and antimicrobial formulation development. The chapters have been organized from a general introductory review to approaches of mixing other antimicrobials and materials to enhance silver performance. This is followed by synthetic approaches. First are biogenic (sometimes called green or eco-friendly) approaches, followed by advanced physical–chemical synthetic approaches. The book ends with an overview of applications through a review of patents over the past 10 years.
nanotechnology --- environmentally-friendly --- pesticide --- antimicrobial --- zebrafish --- antimicrobial activity --- biofilm --- urinary infection --- silver nanoparticles --- bacterial resistance --- silver --- nanoparticles --- Candida albicans --- Staphylococcus aureus --- herbal medicine --- Punicaceae --- calcium glycerophosphate --- Streptococcus mutans --- antibacterial --- titania --- mesoporous --- macroporous --- surface functionalization --- camphor derivatives --- silver camphorimine complexes --- laser ablation synthesis in solution --- nano-antimicrobials --- food packaging --- green synthesis --- microwave irradiation --- Juglans regia --- antibacterial activity --- biological synthesis --- multidrug-resistant bacteria --- antifungal --- chitosan oligomers --- composites --- deep eutectic solvents --- phenolic compounds --- Phytophthora cinnamomi --- root rot --- non-equilibrium plasma --- antibacterial coatings --- plasma polymers --- nanocomposites --- antibiotics --- adjuvant --- combinatorial --- metal --- ROS --- antibacterial effect --- laser irradiation --- metal-vapour method --- TEM --- XPS --- EXAFS --- microbiomes --- silane-based coating --- Marinomonas --- Anaerospora --- antibiotic resistance --- medicinal silver --- patents --- synergism --- Cephradine --- Vildagliptin --- n/a
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Medicinal plants have been used for the maintenance of human health since ancient times, in the form of food, spices, and traditional medicines. Medicinal plant-based traditional medicines serve as the primary healthcare systems in various countries even in recent times. Alongside this, medicinal plants have also served as the one of the main sources for the discovery of new therapeutic agents. At present, various plant extracts and their isolated phytochemicals are screened and evaluated for their diverse pharmacological activities related to both communicable and non-communicable diseases. However, comparatively little focus is given to the detailed mechanism of action of these agents on the molecular level. Molecular mechanism-based studies are essential for the development of evidence-based traditional medicines as well as for the development of isolated natural products as the lead candidates for novel drug discovery. This main focus of this Special Issue “Plant-based Bioactive Natural Products: Insights into Molecular Mechanisms of Action” is to cover the recent advances in science related to the molecular mechanisms of action of natural products. A total of nine articles were published in this Special Issue, including two original research articles and two review articles. This Special Issue has provided some new experimental data on bioactive natural products and their detailed mechanisms of action for biological activities. Similarly, review articles have provided state-of-the-art information on the related topics. I would like to thank all the authors for submitting their manuscripts and the reviewers and editors for their contribution to this Special Issue. Furthermore, I am also grateful to the handling editors and staffs of Applied Sciences for their support during the preparation and finalization of this Special Issue.
foodborne diseases --- giardiasis --- herbal drugs --- ethnobotany --- toxoplasmosis --- srophularia buergeriana --- cognitive impairment --- amyloid beta --- tau phosphorylation --- oxidative stress --- anti-apoptotic --- Terminalia chebula fruit --- osteoarthritis --- AyuFlex® --- cartilage collapse --- MMPs --- inflammation response --- vascular inflammation --- liensinine --- VSMC --- macrophage --- proliferation --- migration --- Nigella sativa --- methicillin-resistant --- Staphylococcus aureus --- synergism --- beta-lactam --- antibiotics --- artichoke by-products --- phenolic compounds --- HPLC-ESI-TOF-MS --- PLE --- GRAS --- Scrophularia buergeriana --- anti-amnesic effect --- cholinergic neurotransmission --- anti-oxidant --- anti-inflammation --- Vepris macropylla --- essential oil --- citral --- antiproliferative activity --- fluorescence and scanning electron microscopy --- human breast cancer cell line --- Vaccinium species --- phytochemicals --- berry --- leaf --- anti-inflammatory pathways --- endothelial dysfunction --- natural products --- bioactive compounds --- medicinal plants --- bioactivity --- mechanism of action --- traditional medicines
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Savannas and woodlands are one of the most challenging targets for remote sensing. This book provides a current snapshot of the geographical focus and application of the latest sensors and sensor combinations in savannas and woodlands. It includes feature articles on terrestrial laser scanning and on the application of remote sensing to characterization of vegetation dynamics in the Mato Grosso, Cerrado and Caatinga of Brazil. It also contains studies focussed on savannas in Europe, North America, Africa and Australia. It should be important reading for environmental practitioners and scientists globally who are concerned with the sustainability of the global savanna and woodland biome.
Savanna --- alternative stable states --- MODIS VCF --- land surface temperature --- albedo --- Cerrado --- Amazon --- vegetation type --- optical --- sar --- synergism --- mapping --- savanna --- post oak --- vegetation index --- ecosystem function --- phenology --- encroachment --- evergreen --- deciduous --- vegetation --- grassland --- fractional cover --- trend --- ecoregion --- bare soil --- livestock --- production systems --- remote sensing --- vegetation dynamics --- vegetation persistence --- conservation --- savannas --- Africa --- vegetation indices --- oak-grass savanna --- hydrology --- Sentinel-2 --- land cover --- grasslands --- forests --- monitoring --- random forest --- spectral indexes --- vegetation seasonality --- aboveground biomass --- Cerrado ecosystem --- SAR --- allometry --- biomass --- carbon --- cost-effective --- LiDAR --- TLS --- plant water availability --- tree phenology --- phenocams --- MODIS --- terrestrial laser scanning (TLS) --- Above Ground Biomass (AGB) --- 3D point cloud --- vegetation structure --- n/a
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In many parts of the world, freshwater is a subject of frequent and intense large-scale disturbances. Pollution, water withdrawal, alteration of freshwater flows, road construction, aquifer mining, surface water diversion, desertification, wetland drainage, soil erosion in agriculture, deforestation, and dam building have led to some irreversible species losses and severe changes in community compositions of freshwater ecosystems. Pollution represents one of the most relevant impacts on freshwater environments, ranging from surface water bodies—such as springs, streams, rivers, lakes, and intermittent waterbodies—to groundwater and transitional habitats between surface waters and groundwaters. The origins and fates of pollutants are different and depend on various pollutants, including fertilizers with pesticides in agricultural areas, heavy metals, chlorinated organic compounds, and polycyclic aromatic hydrocarbons (PAHs), which are predominantly derived from industrial and urban settlements. Another pollutant is microplastics, which can increase in concentration in freshwater bodies and constitute emerging contaminants in freshwater systems when taken together with pharmaceuticals, personal care products (PCPs), and endocrine-disrupting compounds (EDCs). The broad distribution of several pollutants leads to significant changes of freshwater ecosystems, together with the extinction of the most sensitive species or the drastic lowering in abundances of others, thus altering community compositions and the ecosystem services provided by freshwater biodiversity.
multiple stressors --- pesticides --- freshwater ecology --- ecotoxicology --- synergism --- resource limitation --- population density --- groundwater --- karst aquifer --- pollution --- quarry --- Apuan Alps --- groundwater ecology --- stygofauna --- stygobite --- aquifer --- syncarida --- crustaceans --- copepods --- stygobiotic --- traits --- nitrate --- ammonium --- nitrite --- nitrogen --- contamination --- AQUALIFE software --- groundwater dependent ecosystems --- threats --- biodiversity --- abundance-size scaling theory --- benthos --- hyporheos --- freshwater communities --- pharmaceuticals --- large scale survey --- Biolog EcoPlatesTM --- flow cytometry --- microbial community --- metabolic fingerprint --- groundwater quality --- hydrogeochemistry --- Chironomidae --- Chironomus plumosus larvae --- mentum deformities --- freshwater contamination --- Lake Trasimeno --- platinum --- bioaccumulation --- passive sample --- freshwater clam --- Corbicula fluminalis africana --- diet --- Triturus carnifex --- mountain karst ponds --- microplastics --- heavy metals --- EOCs --- landfill --- marble slurry --- neonicotinoids --- software
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Carotenoids are a group of natural pigments, consisting of more than 750 compounds. They are mostly yellow, orange, or red in color, due to the system of conjugated double bonds. This structural element is also responsible for the good antioxidant properties of many carotenoids. Carotenoids have shown numerous biological activities (not only as provitamin A), e.g., preventive properties of fruits and vegetables. As lipophilic compounds, their uptake and storage in the body are dependent on various conditions. In vitro and in vivo data showed stimulating and inhibitory effects of matrix compounds on bioaccessibility and bioavailability of carotenoids.
singlet-triplet annihilation --- silicon carotenoids --- dye-sensitized solar cells --- spent coffee grounds --- astaxanthin --- antioxidant antagonism --- carotenoid and chlorophyll derivatives --- fluorocarotenoids --- RNS --- feed processing --- ?-carotene --- iodocarotenoids --- hydrophilic --- selenium carotenoids --- free radical kinetics --- mechanisms --- stability --- free radicals --- antioxidant --- soil amendment --- pressurized fluid extraction --- extraction --- metal ions --- lutein --- lettuce --- lycopene --- antioxidant synergism --- iron carotenoids --- ROS --- solubility --- flavonoids --- bromocarotenoids --- sulfur carotenoids --- marine carotenoids --- cationic lipid --- carotenoids --- antioxidants --- nelfinavir --- fruit --- SK-Hep-1 --- carotenoid --- storage --- vegetables --- ethanol --- exon skipping --- inflammation --- xanthophylls --- Duchenne muscular dystrophy --- pharmacokinetics --- carrots --- chlorocarotenoids --- chelating compound --- cardiovascular disease --- ageing --- accelerated solvent extraction --- nitrogen carotenoids --- VEGF --- chlorophyll --- liquid chromatography --- antiradical --- PEG conjugates --- injection solvent --- cycloaddition --- HIV --- esterification --- antisense oligonucleotide --- B16F10 --- interaction --- cancer chemoprevention --- antireductant --- PC-3 --- oxidative stress
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According to a report from the U.S. Centers for Disease Control and Prevention (CDC), achieving safe and healthier foods was one of the top ten achievements of public health in the 20th century. However, considerable persisting challenges currently exist in developed nations and developing economies for further assuring the safety and security of the food supplies. According to CDC estimates, as many as 3000 American adults, as an example, and based on a recent epidemiological estimate of the World Health Organization, around 420,000 individuals around the globe, lose their lives annually due to foodborne diseases. This emphasizes the need for innovative and emerging interventions, for further prevention or mitigation of the risk of foodborne microbial pathogens during food processing and manufacturing. The current publication discusses recent advancements and progress in the elimination and decontamination of microbial pathogens during various stages of manufacturing and production. Special emphasis is placed on hurdle validation studies, investigating decontamination of non-typhoidal Salmonella enterica serovars, various serogroups of Shiga toxin-producing Escherichia coli, public health-significant serotypes of Listeria monocytogenes, and pathogenic species of Cronobacter.
n/a --- bacteria --- stainless steel --- Escherichia coli --- biofilm formation --- beef --- powdered infant formula --- bile acids --- stx-subtypes --- raw milk --- Shiga toxin-producing Escherichia coli --- Cronobacter sakazakii --- synergism of mild heat and pressure --- raspberry --- blueberry --- biocidal effectiveness --- salmonellosis --- Listeria monocytogenes --- small fruits --- biosensors --- food borne pathogens --- grape --- postharvest diseases --- modified atmosphere packaging --- high hydrostatic pressure --- epithelial barrier --- carvacrol --- dietary bioactive components --- rapid detection --- essential oils --- ozon --- stx-genes --- Cronobacter outbreaks --- habituation --- plant extracts --- Escherichia coli (STEC) --- ozonated water --- disinfectants --- caprylic acid --- foodborne pathogens --- temperature --- natural background microflora --- preventive measures --- carbon dioxide --- nitrogen --- strawberry --- high-pressure pasteurization --- gut microbiota --- food safety --- Shiga toxin-producing Escherichia coli (STEC) --- microfluidic chip --- fungi --- blackberry --- serogroups --- infant care setting --- non-ozonated water --- Food contamination. --- Food --- Microbiology. --- Sanitary microbiology --- Contaminated food --- Foods, Contaminated --- Contamination (Technology) --- Food adulteration and inspection --- Bacteriology --- Contamination
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Carbon materials are one of the most fascinating materials because of their unique properties and potential use in several applications. They can be obtained from residues or by using advanced synthesis technologies like chemical vapor deposition. The carbon family is very broad, ranging from classical activated carbons to more advanced species such as carbon nanotubes and graphene. The surface chemistry is one of the most interesting aspects of this broad family of materials, which allows the incorporation of different types of chemical functionalities or heteroatoms on the carbon surface, such as O, N, B, S, or P, which can modify the acid–base character, hydrophobicity/hydrophilicity, or the electronic properties of these materials and, thus, determine the final application. This book represents a collection of original research articles and communications focused on the synthesis, properties, and applications of heteroatom-doped functional carbon materials.
targeted adsorption --- graphene oxide --- bonding type --- oxygen reduction reaction (ORR) --- doping --- catalysis --- porous carbon --- Cd(II) --- nitrogen-doped graphene oxide --- sp3-defect --- heteroatoms --- amino group --- nitrogen-doped --- energy storage --- cross-link bond type --- energy power density --- polyaniline --- environmental remediation --- molten salt --- adsorption --- polyphosphates --- microcrystalline cellulose --- carbo microsphere --- Orange G --- carbon materials --- chemical functionalization --- physicochemical properties --- supercapacitor capacitance --- nanoparticles and shallow reservoirs --- pulse laser deposition --- co-activation method --- carbon capture and storage process (CCS) --- biochar --- CO2 --- adsorption studies --- graphene --- polypyrrole --- oxygen peroxide oxidation --- carbon nanotubes --- salt and base --- nanofluids --- carbon gels --- bio-phenol resin --- synergism --- magnetic moment --- photocatalysis --- oxygen reduction reaction --- carbon dioxide --- surface chemistry --- functionalized graphene oxide --- nitrogen-doped carbon materials --- N–doped carbon --- p-phenylene diamine --- electrochemical analysis --- mesoporosity --- carbon dioxide adsorption --- electrode material --- nitrogen-doped graphene --- nitrogen and oxygen doped activated carbon --- electrocatalysis --- supercapacitor
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The global biodiversity and climate emergencies demand transformative changes to human activities. For example, food production relies on synthetic, industrial and non-sustainable products for managing pests, weeds and diseases of crops. Sustainable farming requires approaches to managing these agricultural constraints that are more environmentally benign and work with rather than against nature. Increasing pressure on synthetic products has reinvigorated efforts to identify alternative pest management options, including plant-based solutions that are environmentally benign and can be tailored to different farmers’ needs, from commercial to small holder and subsistence farming. Botanical insecticides and pesticidal plants can offer a novel, effective and more sustainable alternative to synthetic products for controlling pests, diseases and weeds. This Special Issue reviews and reports the latest developments in plant-based pesticides from identification of bioactive plant chemicals, mechanisms of activity and validation of their use in horticulture and disease vector control. Other work reports applications in rice weeds, combination biopesticides and how chemistry varies spatially and influences the effectiveness of botanicals in different locations. Three reviews assess wider questions around the potential of plant-based pest management to address the global challenges of new, invasive and established crop pests and as-yet underexploited pesticidal plants.
antifeedant --- encapsulation --- induced systemic response --- corn --- barnyard grass --- rutin --- deguelin --- botanical pesticides --- insect behavior --- organic farming --- aphids --- leaf disc assay --- Melia volkensii --- rotenoids --- botanicals --- entomopathogenic fungi --- anise --- oil emulsion entrapment --- integrated pest management --- sesquiterpene --- botanical pesticide --- pest management --- neem --- insecticidal activity --- insect pest --- insects --- resistance --- biopesticide --- Tetranychus urticae --- karanja --- Colorado potato beetle --- essential oils --- Y-tube olfactometer --- parasitoid --- pests --- chemotype 3 --- limonoid --- prospects --- pyrethrum --- botanical insecticides --- weed control --- cover crops --- agro-ecological intensification --- spatial-temporal variation --- survival analysis --- Senecio fistulosus --- organic pesticide --- synergism --- growth inhibitor --- biopesticides --- tryptophan --- acaricide --- pyrrolizidine alkaloid --- phytotoxic activity --- phenylalanine --- rice --- Meliaceae --- invasive species --- botanical active substances --- structure-activity relationships --- pesticidal plant --- fennel --- spray drying --- foliar fertiliser --- sustainable agriculture --- Italian ryegrass
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Natural products are bioactive compounds synthesized by terrestrial and marine plants, microorganisms and animals, whose main objective is to prevent them from attacks by predators and/or pathogens. Traditionally since ancient times, different cultures have used these compounds for the prevention and treatment of various human diseases. During the last few years, it has been reported that most of these phytochemicals possess a variety of interesting and significant biological properties, such as analgesic, antiallodynic, antidiabetic, antioxidant, antiparasitic, antimicrobial, antiviral, antiatherogenic, anti-inflammatory, antiproliferative, antitumor and normal growth stimulants, as well as significant cardioprotective and neuroprotective activity. This thematic book aims to collect and disseminate some of the most significant and recent contributions of the use of the natural compounds called phytochemicals, as well as some of their chemical derivatives, for the prevention and treatment of cancer and other accompanying diseases. On the other hand, in recent years, the synthesis of numerous chemical derivatives of these natural compounds has also intensified, with the aim of enhancing their bioactive capacities. Among all these bioactivities, special attention has been paid to its antitumor capacity through the potential modulation of cancer initiation and growth, cell differentiation, apoptosis and autophagy, angiogenesis, and metastatic dissemination. In addition, a considerable number of studies have linked their anticancer effects to their anti-inflammatory and antioxidant activities.
total phenolic content --- total flavonoid content --- GC-MS --- DPPH --- antioxidant --- anticancer agent --- anti-inflammatory agent --- gingival fibroblasts --- oral cancer --- natural extract --- Adenosma bracteosum --- extract --- anti-cancer --- cell line --- isolated compounds --- caspase-3 --- bioactive compounds --- metabolites --- wine --- grapes --- breast cancer --- chemoprevention --- chemotherapy --- squamous cell carcinoma --- Moringa oleifera --- 3-hydroxy-β-ionone --- antioxidant activity --- antioxidant enzymes --- anti-proliferative activity --- maslinic acid --- melanoma --- Olea europaea L. --- ROS levels --- photodynamic therapy --- cancer --- photosensitiser --- natural compounds --- Elaeagnus angustifolia --- EMT --- apoptosis --- AKT/PI3K signaling pathway --- human hepatocarcinoma HepG2 cells --- migration activity --- proliferation --- oxidative stress --- ROS level --- uvaol --- lung metastases --- in vivo --- complementary medicine --- medicinal mushrooms --- triterpenoic acid --- tormentic acid --- betulinic acid --- oleanolic acid --- rhodamine B --- cytotoxicity --- hepatocellular carcinoma (HCC) --- Pogostemon cablin (PPa extract) --- cell cycle --- synergism --- natural photosensitive compounds --- anticancer activity --- hypericin --- emodin --- quinizarin --- danthron --- interaction --- DNA --- glioblastoma (GBM) --- lactucopicrin (LCTP) --- temozolomide (TMZ) --- autophagy --- NF-κB --- p62/SQSM1 --- natural product --- therapeutic triglyceride --- xenograft study --- Caveolin-1 --- actin cytoskeleton --- betulin glycoconjugates --- click chemistry --- 1,3-dipolar cycloaddition --- n/a
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