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The processes of DNA recombination and repair are vital to cell integrity - an error can lead to disease such as cancer. It is therefore a large and exciting area of research and is also taught on postgraduate and undergraduate courses. This book is not a comprehensive view of the field, but a selection of the issues currently at the forefront of knowledge.
Molecular biology --- moleculaire biologie --- DNA repair --- Genetic recombination
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Genetic recombination --- Genetische recombinatie --- Recombinaison genétique --- Recombination [Genetic ] --- Eukaryotic cells --- Genetic aspects --- Congresses --- Gene expression. --- Recombination, genetic --- Viruses
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Genetic engineering --- Molecular genetics --- Molecular cloning --- Nucleic acids --- Génie génétique --- Génétique moléculaire --- Clonage moléculaire --- Acides nucléiques --- Genetic engineering. --- Molecular cloning. --- Molecular genetics. --- Analysis --- Analyse --- Analysis. --- Cloning, Molecular --- DNA cloning --- Gene cloning --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Polynucleotides --- Genetics --- Molecular biology --- Cloning --- Clone cells --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Biomolecules
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Biotechnologie --- Biotechnology --- Génie génétique --- genetic engineering --- Terminologie --- terminology --- 66.098 <031> --- 575.08:577.21 --- Genetic engineering --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Transgenic organisms --- Chemical engineering --- Biological processes. Biotechnology--Encyclopedieën. Lexica --- Genetic engineering, genetic manipulation, recombinant DNA --- 575.08:577.21 Genetic engineering, genetic manipulation, recombinant DNA --- 66.098 <031> Biological processes. Biotechnology--Encyclopedieën. Lexica
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Animal evolution --- Animals--Evolution --- Animaux--Evolution --- Biological evolution --- Biologische evolutie --- Darwinism --- Darwinisme --- Dieren--Evolutie --- Evolutie (Biologie) --- Evolution (Biologie) --- Evolution (Biology) --- Evolution biologique --- Gene transfer --- Genetic transformation --- Genetische transformatie --- Origin of species --- Transformation (Genetics) --- Transformation génétique --- 575.8 --- Evolution. Origin of species. Phylogeny --- Evolution (Biology). --- Genetic transformation. --- 575.8 Evolution. Origin of species. Phylogeny --- Genetic recombination --- Microbial genetics --- Nucleic acids --- Transfection --- Animals --- Evolutionary biology --- Evolutionary science --- Biology --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny
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Cloning --- Genetic engineering --- Biotechnology. --- Cloning, Molecular. --- Genetic Techniques. --- Cloning. --- Government policy --- Government policy. --- Molecular Cloning --- Biotechnologies --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic engineering and state --- Genetic engineering policy --- State and genetic engineering --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetics --- methods --- Cosmids --- Cloning, Organism --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Reproduction, Asexual --- Science and state --- Genetic Counseling --- Genetic Phenomena --- Cloning, Organism. --- Cloning, Embryo --- Cloning, Human --- Embryo Cloning --- Human Cloning --- Clonings, Embryo --- Clonings, Human --- Clonings, Organism --- Embryo Clonings --- Human Clonings --- Organism Cloning --- Organism Clonings --- Cloning, Molecular --- Nuclear Transfer Techniques
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Integrating advances in molecular biology into bioprocesses presents a continuous challenge to scientists and bioengineers. This series is conceived to help meet this challenge. It examines and assesses the feasibility of new approaches for the modification of cellular function such as gene expression, protein processing, secretion, glycosylation, immortalisation, proliferation, and apoptosis as well as the systematic study of the metabolic genotype-phenotype relationship. The series provides detailed coverage of the methodology for improving cellular properties of cells used in the production of biopharmaceuticals, gene and cell therapies and tissue engineering. It also seeks to explain the cellular mechanisms underlying in vitro physiological activity and productivity. This volume, which is based on presentations at the `European Workshop on Animal Cell Engineering' held in Costa Brava, Spain, contains a collection of chapters relating to cellular function and modification by leading authorities in several different areas of basic research and the biopharmaceutical industry.
Animal cell biotechnology. --- Genetic engineering. --- Genetic regulation. --- Cell proliferation. --- Zoology. --- Biotechnology. --- Cytology. --- Morphology (Animals). --- Biomedical engineering. --- Pharmacy. --- Cell Biology. --- Animal Anatomy / Morphology / Histology. --- Biomedical Engineering and Bioengineering. --- Cell biology. --- Animal anatomy. --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Animal anatomy --- Animals --- Biology --- Physiology --- Cell biology --- Cellular biology --- Cells --- Chemical engineering --- Genetic engineering --- Natural history --- Anatomy --- Animal cells in biotechnology --- Animal biotechnology --- Cell renewal --- Cellular proliferation --- Cell cycle --- Cell division --- Cell populations --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Growth --- Regulation --- Anatomy, Comparative. --- Animal Anatomy.
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Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of ""healthy genes"" into patients' cells. The problem, however, was that viral vectors proved unnecessarily harmful to humans: subjects experienced inflammatory activity and negative immunological responses to the genes. Viral vectors were also unable to meet the needs of the pharmaceutical community: they were not reproducible in large-scale proportions in cost-effective ways.
DNA-ligand interactions. --- Drug targeting. --- Gene therapy. --- Gene therapy. Genetic vectors. DNA-ligand interactions. Liposomes. Drug targeting. --- Genetic transformation. --- Genetic vectors. --- Liposomes. --- Recombination, Genetic --- Genetic Structures --- Genetic Techniques --- Investigative Techniques --- Genetic Phenomena --- Genetic Processes --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Genetic Vectors --- Gene Transfer Techniques --- Transformation, Genetic --- Medicine --- Health & Biological Sciences --- Pathology --- Gene transfer --- Transformation (Genetics) --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Phospholipid vesicles --- Binding, DNA-ligand --- DNA-ligand binding --- Interactions, DNA-ligand --- Therapy, Gene --- Cloning vectors --- Expression vectors (Genetics) --- rDNA vectors --- Recombinant DNA vectors --- Vectors, Genetic --- Targeting --- Genetic recombination --- Microbial genetics --- Nucleic acids --- Transfection --- Target organs (Anatomy) --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Ligand binding (Biochemistry) --- Genetic engineering --- Therapeutics --- Gene expression --- Molecular cloning --- Recombinant DNA --- Dosage forms
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Genetic engineering --- Biotechnology --- Genetic Engineering --- Genetics --- Social Change --- Socioeconomic Factors --- Social aspects --- Genetic Engineering. --- Biotechnology. --- Genetics. --- Social Change. --- Socioeconomic Factors. --- Social aspects. --- Modernization --- Social Development --- Social Impact --- Change, Social --- Changes, Social --- Development, Social --- Developments, Social --- Impact, Social --- Impacts, Social --- Social Changes --- Social Developments --- Social Impacts --- Factors, Socioeconomic --- High-Income Population --- Inequalities --- Land Tenure --- Standard of Living --- Factor, Socioeconomic --- High Income Population --- High-Income Populations --- Inequality --- Living Standard --- Living Standards --- Population, High-Income --- Populations, High-Income --- Socioeconomic Factor --- Tenure, Land --- Biotechnologies --- Engineering, Genetic --- Intervention, Genetic --- Genetic Intervention --- Genetic Interventions --- Interventions, Genetic --- Designed genetic change --- Gene splicing --- Genetic intervention --- Genetic surgery --- Group Processes --- Genetic Structures --- Genetic Phenomena --- Economics --- Cloning, Molecular --- DNA, Recombinant --- Industrial Microbiology --- Artificial Gene Fusion --- Organisms, Genetically Modified --- Animals, Genetically Modified --- Plants, Genetically Modified --- Chemical engineering --- Genetic recombination --- Transgenic organisms --- Social Sciences - General --- Social Inequalities --- Social Inequality --- Inequalities, Social --- Inequality, Social --- Economic and Social Factors --- Social and Economic Factors --- Socioeconomic Characteristics --- Characteristic, Socioeconomic --- Socioeconomic Characteristic
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Examines the ethical, legal, and policy issues associated with the commercialization of genetic research and will be of interest to the academic community (law, ethics, medicine and genetics) and the biotechnology industry, as well as those actively involved in genetic research. The linkage between industry and human genetics has given rise to numerous issues associated with the commercialization process. The topics covered will include commercialization and the university, commercialization and patents, clones and xenotransplants, the public perception of genetics, the role of the media, commercialization, confidentiality, and conflicts of interest, regulating the commercial environment, and the role of research ethics boards.
Genetic engineering --- -Genetics --- -Intellectual property --- -#GBIB:CBMER --- 575 --- 66.098 --- 174.4 --- Intellectual property --- IP (Intellectual property) --- Proprietary rights --- Rights, Proprietary --- Intangible property --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Law and legislation --- -Moral and ethical aspects --- Research --- -Government policy --- -Law and legislation --- Genetics --- Moral and ethical aspects --- Government policy --- -Genetic engineering --- #GBIB:CBMER --- Life sciences. --- Ethics. --- Law. --- Life Sciences, general. --- Law, general. --- Acts, Legislative --- Enactments, Legislative --- Laws (Statutes) --- Legislative acts --- Legislative enactments --- Jurisprudence --- Legislation --- Deontology --- Ethics, Primitive --- Ethology --- Moral philosophy --- Morality --- Morals --- Philosophy, Moral --- Science, Moral --- Philosophy --- Values --- Biosciences --- Sciences, Life --- Science
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