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Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.

CpG Islands --- DNA, Bacterial --- Adjuvants --- immunology --- Immunologic --- immunology. --- Immunologic. --- Immunology. --- Immuno competent cells. --- Antigen presenting cells. --- Cellular immunity. --- Immune response. --- T cells. --- Adjuvants, Immunologic. --- Antigen-Presenting Cells --- Immunity, Cellular. --- Vaccines, DNA. --- Microbiology. --- Cancer research. --- Cancer Research. --- Cancer research --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology

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This Cancer Prevention book series aims to complement the research reported in the journal Cancer Causes and Control. Volumes in this series will summarize the state of the science from causes to prevention of cancer. The scope will be international. The past 20 years has seen an explosion of epidemiologic material on the causes of cancer. Examples include the growing number of studies of physical activity and colon cancer which have emerged and the numerous studies of components of diet such as alcohol and the risk of specific cancers. Major shifts in resource allocation now focus on translation of this new knowledge to actual cancer prevention programs. Researchers, practicing clinicians, and those who write and implement public health policy need this information summarized in an easily accessible format. The abundance of knowledge, increasing understanding of how to communicate risk of cancer to the public, and greater public awareness of cancer, make the coming years ones in which we will see many new attempts at widespread cancer prevention programs. For example, the U.S. Centers for Disease Control and Prevention launched a national colon cancer awareness campaign in early 1999.

Cancer --- Carcinogenesis. --- Prevention. --- Medicine. --- Cancer research. --- Public health. --- Epidemiology. --- Biomedicine. --- Cancer Research. --- Public Health. --- Oncology. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Diseases --- Public health --- Cancer research --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Pathology --- Genetic toxicology --- Pathogenesis

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This book describes all human leukemia-lymphoma cell lines that have been established and that grow continuously under standardised in vitro conditions. These lines are derived from cells belonging to all the major hematopoietic cell lineages, i.e. B- and T-lymphocytes, natural killer cells, granulocytic cells and megakaryocytic cells. The clinical data, the culture conditions and the major phenotypic features of the cell lines are described with citations. This book is the first book describing human leukemia-lymphoma cell lines and will be of interest to scientists involved in the areas of hematology, oncology, immunology, molecular biology and cytogenetics. Cancer Cell Lines, Volumes 1-3: These 3 volumes provide a comprehensive text on the culture of established cell lines from every type of human cancer. The volumes provide a basic manual and reference resource for every cancer research scientist using human cancer cells.

Human cell culture. --- Cancer cells. --- Cell lines. --- Oncology. --- Oncology  . --- Cytology. --- Hematology. --- Pathology. --- Cancer Research. --- Cell Biology. --- Cancer research. --- Cell biology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Haematology --- Internal medicine --- Blood --- Cell biology --- Cellular biology --- Biology --- Cells --- Tumors --- Cancer research --- Cancer cells --- Human cell culture --- Cell culture --- Pathology, Cellular

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Nature Reviews Molecular Cell Biology is the leading monthly review journal in the field of molecular and cell biology. With its extraordinary breadth and depth of coverage, the journal provides a unique resource of information, opinion and commentary for cutting-edge molecular and cell biology research. All Reviews, Perspectives and Progress articles are carefully commissioned, written by leaders in the field, and subject to rigorous peer review — which results in timely and authoritative articles. In addition, articles are edited and the diagrams redrawn by professional art editors, which makes for highly readable, visually attractive articles that are accessible to specialists and non-specialists alike.

Molecular biology --- Cytology --- Cytologie --- Biologie moléculaire --- Periodicals. --- Périodiques --- Cytology. --- Molecular biology. --- Cells. --- Molecular Biology. --- 57 --- 577.21 --- 576 --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Cell --- Cell Biology --- Biological sciences in general --- Molecular mechanism of coding, storage and realization of inheritance information. Molecular genetics. Molecular biology of the gene --- Cellular and subcellular biology. Cytology --- Periodicals --- Chemistry --- Life Sciences --- Biochemistry --- Biology --- General and Others --- Genetic Phenomena --- 576 Cellular and subcellular biology. Cytology --- 577.21 Molecular mechanism of coding, storage and realization of inheritance information. Molecular genetics. Molecular biology of the gene --- Biologie moléculaire --- Périodiques --- EBSCOASP-E EJBIOMO EJMEDEC EPUB-ALPHA-N EPUB-PER-FT MDBIOCHE MDCYTOLO NPG-E --- Cell biology --- Cellular biology --- Molecular biochemistry --- Molecular biophysics --- Cells --- Cytologists --- Biophysics --- Biomolecules --- Systems biology --- Histology. --- moleculaire biologie --- Cancer research --- Life sciences --- Stem cells --- Developmental biology --- Life Sciences, general --- Cancer Research --- Developmental Biology --- Stem Cells --- Biochemistry, general --- Development (Biology) --- Growth --- Ontogeny --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Medical sciences --- Biosciences --- Sciences, Life --- Science --- Composition --- MDBIOCHE MDCYTOLO --- Molecular Biology