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Rethinking homeostasis : allostatic regulation in physiology and pathophysiology
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ISBN: 0262194805 0262283271 0585446601 0262293587 9780262283274 9780585446608 9780262194808 9780262293587 Year: 2003 Publisher: Cambridge, Mass. : MIT Press,

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Abstract

Homeostasis, a key concept in biology, refers to the tendency toward stability in the various bodily states that make up the internal environment. Examples include temperature regulation and oxygen consumption. The body's needs, however, do not remain constant. When an organism is under stress, the central nervous system works with the endocrine system to use resources to maintain the overall viability of the organism. The process accelerates the various systems' defenses of bodily viability, but can violate short-term homeostasis. This allostatic regulation highlights our ability to anticipate, adapt to, and cope with impending future events. In Rethinking Homeostasis, Jay Schulkin defines and explores many aspects of allostasis, including the wear and tear on tissues and accelerated pathophysiology caused by allostatic overload. Focusing on the concept of motivation and its relationship to the central nervous system function and specific hormonal systems, he applies a neuroendocrine perspective to central motive states such as cravings for water, sodium, food, sex, and drugs. He examines in detail the bodily consequences of the behavioral and neuroendocrine regulation of fear and adversity, the endocrine regulation of normal and preterm birth, and the effects of drug addiction on the body. Schulkin's presentation of allostasis lays the foundation for further study.

Keywords

Homeostasis. --- Neuroendocrinology. --- Psychophysiology. --- Biological control systems. --- Neurosecretory Systems --- Behavioral Sciences --- Endocrine System --- Nervous System --- Physiological Processes --- Psychological Phenomena and Processes --- Mind-Body Therapies --- Physiology --- Psychiatry and Psychology --- Physiological Phenomena --- Behavioral Disciplines and Activities --- Anatomy --- Complementary Therapies --- Biological Science Disciplines --- Natural Science Disciplines --- Therapeutics --- Phenomena and Processes --- Disciplines and Occupations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Psychophysiology --- Homeostasis --- Human Anatomy & Physiology --- Health & Biological Sciences --- physiology. --- Autoregulation --- Mind-Body Relationship (Physiology) --- Physiologic Psychology --- Physiological Psychology --- Psychology, Physiologic --- Mind-Body Relations (Physiology) --- Psychology, Physiological --- Mind Body Relations (Physiology) --- Mind Body Relationship (Physiology) --- Mind-Body Relation (Physiology) --- Mind-Body Relationships (Physiology) --- Physiologic Psychologies --- Psychologies, Physiologic --- Relation, Mind-Body (Physiology) --- Relations, Mind-Body (Physiology) --- Relationship, Mind-Body (Physiology) --- Relationships, Mind-Body (Physiology) --- Neuroendocrine System --- Neuroendocrine Systems --- Neurosecretory System --- System, Neuroendocrine --- System, Neurosecretory --- Systems, Neuroendocrine --- Systems, Neurosecretory --- Therapy --- Treatment --- Therapeutic --- Therapies --- Treatments --- Disease --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Alternative Therapies --- Therapy, Alternative --- Therapy, Complementary --- Alternative Medicine --- Complementary Medicine --- Medicine, Alternative --- Medicine, Complementary --- Therapies, Alternative --- Therapies, Complementary --- Anatomies --- Physiological Concepts --- Physiological Phenomenon --- Physiological Process --- Concept, Physiological --- Concepts, Physiological --- Phenomena, Physiological --- Phenomenas, Physiological --- Phenomenon, Physiological --- Physiological Concept --- Process, Physiological --- Processes, Physiological --- Mind-Body Medicine --- Mind Body Medicine --- Mind Body Therapies --- Mind-Body Therapy --- Therapies, Mind-Body --- Therapy, Mind-Body --- Psychologic Processes and Principles --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Endocrine Systems --- System, Endocrine --- Systems, Endocrine --- Proxemics --- Behavioral Science --- Proxemic --- Science, Behavioral --- Sciences, Behavioral --- Biocybernetics --- Biofeedback --- Biological cybernetics --- Biological regulation --- Control biophysics --- Control systems, Biological --- Control theory in biology --- Regulation, Biological --- Behavioral physiology --- Physiological psychology --- Physiopsychology --- Somatopsychics --- therapy --- Psychosomatic Medicine --- Mind-Body Relations, Metaphysical --- Neurosecretion --- Spiritual Therapies --- Psychologic Processes --- Psychological Processes --- Phenomena, Psychological --- Processes, Psychologic --- Processes, Psychological --- Psychological Phenomenas --- Psychological Processe --- Biological systems --- Control theory --- Cybernetics --- Feedback control systems --- Nervous system --- Psychobiology --- Mind and body --- Endocrinology --- Neurology --- Neurohormones --- Biological control systems --- Body fluids --- NEUROSCIENCE/General

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